Patents by Inventor Martin Elbs

Martin Elbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9399016
    Abstract: The invention provides a peptide derivative of formula A-B-C wherein A is a polycationic nucleic acid-binding component; B is a spacer element peptide that is susceptible to cleavage within a cell; and C is a cell surface receptor binding component. The invention also provides a lipid derivative of general formula (I): (PEG)q-Linker-Spacer-Cationic headgroup-carbon skeleton-(hydrophobic chain)o wherein: the Linker is a group susceptible to cleavage within a cell; the Spacer is a group linking the Linker to the Cationic headgroup; q denotes the number of PEG chains and q=1, 2 or 3; o denotes the number of hydrophobic chains and o=1, 2 or 3; the carbon skeleton is a group linking the hydrophobic chains to the cationic headgroup. The peptide and lipid derivatives find use in non-viral gene delivery systems.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: July 26, 2016
    Assignee: UCL BUSINESS PLC
    Inventors: Stephen Lewis Hart, Stephanie Grosse, Alethea Bernice Tabor, John Bosco Wong, Martin Elbs, Helen Claire Hailes, Mohd Firouz Mohd Mustapa
  • Patent number: 9074050
    Abstract: The present invention relates to a continuous process for the production of polymeric coupling products by using a reactor assembly which is equipped with two or more reaction cells. The educt fluid is pumped through the reaction cells and thoroughly mixed therein by means of agitators. Preferably the process according to the invention is used for the preparation of coupling products which show at least partially precipitation and/or gelation effects during the performance of the synthesis. The precipitation and/or gelation effects are associated with and increase of the viscosity of the reaction system under reaction conditions. The products which are obtained by the process according to the invention have increased molecular weight and low polydispersity over similar products which were obtained in batch experiments.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: July 7, 2015
    Assignee: BASF SE
    Inventors: Matthias Kleiner, Martin Elbs, Marcel Kastler
  • Patent number: 8835579
    Abstract: The present invention relates to a process for polymerizing (hetero)aromatic compounds under formation of aryl-aryl C—C couplings for preparing conjugated polymers with high molecular weight and high regioregularity, and to novel polymers obtainable by this process. The invention further relates to the use of the novel polymers as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors (FETs), thin film transistors (TFT), electroluminescent, photovoltaic and sensor devices.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: September 16, 2014
    Assignee: BASF SE
    Inventors: Pascal Hayoz, Mathias Dueggeli, Martin Elbs, Olivier Frederic Aebischer, Achim Lamatsch
  • Publication number: 20140080994
    Abstract: The present invention relates to a continuous process for the production of polymeric coupling products by using a reactor assembly which is equipped with two or more reaction cells. The educt fluid is pumped through the reaction cells and thoroughly mixed therein by means of agitators. Preferably the process according to the invention is used for the preparation of coupling products which show at least partially precipitation and/or gelation effects during the performance of the synthesis. The precipitation and/or gelation effects are associated with and increase of the viscosity of the reaction system under reaction conditions. The products which are obtained by the process according to the invention have increased molecular weight and low polydispersity over similar products which were obtained in batch experiments.
    Type: Application
    Filed: May 29, 2012
    Publication date: March 20, 2014
    Applicant: BASF SE
    Inventors: Matthias Kleiner, Martin Elbs, Marcel Kastler
  • Publication number: 20120142872
    Abstract: The present invention relates to a process for polymerising (hetero)aromatic compounds under formation of aryl-aryl C—C couplings for preparing conjugated polymers with high molecular weight and high regioregularity, and to novel polymers obtainable by this process. The invention further relates to the use of the novel polymers as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors (FETs), thin film transistors (TFT), electroluminescent, photovoltaic and sensor devices.
    Type: Application
    Filed: May 18, 2010
    Publication date: June 7, 2012
    Applicant: BASF SE
    Inventors: Bernd Lamatsch, Achim Lamatsch, Pascal Hayoz, Mathias Dueggeli, Martin Elbs, Olivier Frederic Aebischer
  • Publication number: 20100184831
    Abstract: The invention provides a peptide derivative of formula A-B-C wherein A is a polycationic nucleic acid-binding component; B is a spacer element peptide that is susceptible to cleavage within a cell; and C is a cell surface receptor binding component. The invention also provides a lipid derivative of general formula (I): (PEG)q-Linker-Spacer-Cationic headgroup-carbon skeleton-(hydrophobic chain)o wherein: the Linker is a group susceptible to cleavage within a cell; the Spacer is a group linking the Linker to the Cationic headgroup; q denotes the number of PEG chains and q=1, 2 or 3; o denotes the number of hydrophobic chains and o=1, 2 or 3; the carbon skeleton is a group linking the hydrophobic chains to the cationic headgroup. The peptide and lipid derivatives find use in non-viral gene delivery systems.
    Type: Application
    Filed: May 30, 2007
    Publication date: July 22, 2010
    Inventors: Stephen Lewis Hart, Stephanie Grosse, Alethea Bernice Tabor, John Bosco Wong, Martin Elbs, Helen Claire Hailes, Mohd Firouz Mohd Mustapa