Patents by Inventor Martin Emanuele

Martin Emanuele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING EYE DISEASES
    Publication number: 20240066151
    Abstract: Disclosed herein are therapeutic agents capable of increasing the expression level of ELOVL2. Also described herein are therapeutic agents that reduce or slow an aging phenotype. Methods for treating age-related eye diseases or conditions are also provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more therapeutic agents are provided.
    Type: Application
    Filed: September 20, 2023
    Publication date: February 29, 2024
    Inventors: Christopher Chavez, Martin Emanuele
  • SOLID FORMS OF CANNABIDIOL AND USES THEREOF
    Publication number: 20230404939
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms.
    Type: Application
    Filed: June 20, 2022
    Publication date: December 21, 2023
    Applicant: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock-Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • ELOVL2 constructs for human gene therapy
    Patent number: 11793890
    Abstract: Disclosed herein are therapeutic agents capable of increasing the expression level of ELOVL2. Also described herein are therapeutic agents that reduce or slow an aging phenotype. Methods for treating age-related eye diseases or conditions are also provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more therapeutic agents are provided.
    Type: Grant
    Filed: August 24, 2022
    Date of Patent: October 24, 2023
    Assignee: Visgenx, Inc.
    Inventors: Christopher Chavez, Martin Emanuele
  • ELOVL2 CONSTRUCTS FOR HUMAN GENE THERAPY
    Publication number: 20230065365
    Abstract: Disclosed herein are therapeutic agents capable of increasing the expression level of ELOVL2. Also described herein are therapeutic agents that reduce or slow an aging phenotype. Methods for treating age-related eye diseases or conditions are also provided. Methods for treating an age-related eye disease or condition in a subject by administering one or more therapeutic agents are provided.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 2, 2023
    Inventors: Christopher Chavez, Martin Emanuele, Santosh Vetticaden
  • Solid forms of cannabidiol and uses thereof
    Patent number: 11364202
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms. Cocrystals of cannabidiol and a coformer selected from L-proline, D-proline, tetramethylpyrazine, and 4,4?-dipyridyl are also disclosed herein.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: June 21, 2022
    Assignee: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock-Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • Poloxamer composition free of long circulating material and methods for production and uses thereof
    Patent number: 11155679
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: October 26, 2021
    Assignee: LifeRaft Biosciences, Inc.
    Inventors: R. Martin Emanuele, Mannarsamy Balasubramanian, Stewart V. Smith
  • SOLID FORMS OF CANNABIDIOL AND USES THEREOF
    Publication number: 20210299048
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms.
    Type: Application
    Filed: March 31, 2020
    Publication date: September 30, 2021
    Applicant: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • Solid forms of cannabidiol and uses thereof
    Patent number: 10604467
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms. Cocrystals of cannabidiol and a coformer selected from L-proline, D-proline, tetramethylpyrazine, and 4,4?-dipyridyl are also disclosed herein.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: March 31, 2020
    Assignee: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock-Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • POLOXAMER COMPOSITION FREE OF LONG CIRCULATING MATERIAL AND METHODS FOR PRODUCTION AND USES THEREOF
    Publication number: 20200055983
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Application
    Filed: October 23, 2019
    Publication date: February 20, 2020
    Applicant: LifeRaft Biosciences, Inc.
    Inventors: R. Martin Emanuele, Mannarsamy BALASUBRAMANIAN, Stewart V. SMITH
  • Poloxamer composition free of long circulating material and methods for production and uses thereof
    Patent number: 10501577
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: December 10, 2019
    Assignee: LifeRaft Biosciences, Inc.
    Inventors: R. Martin Emanuele, Mannarsamy Balasubramanian, Stewart V. Smith
  • NEW SOLID FORMS OF CANNABIDIOL AND USES THEREOF
    Publication number: 20190300466
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 3, 2019
    Applicant: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock-Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • NEW SOLID FORMS OF CANNABIDIOL AND USES THEREOF
    Publication number: 20190177258
    Abstract: Disclosed herein are cocrystals of cannabidiol and a coformer containing 5-6 membered rings comprised of carbon and nitrogen atoms, wherein the 5-6 membered rings can be unsaturated or saturated and the rings contain 1 to 2 nitrogen atoms.
    Type: Application
    Filed: December 10, 2018
    Publication date: June 13, 2019
    Applicant: Artelo Biosciences, Inc.
    Inventors: R. Martin Emanuele, Tanise Shattock Gordon, Tabitha Williford, Mark Andres, Patricia Andres
  • REDUCED SODIUM POLOXAMER-188 FORMULATIONS AND METHODS FOR USE
    Publication number: 20190076466
    Abstract: Provided is a sterile, injectable solution comprising: poloxamer 188 and water for injection, wherein the sterile, injectable solution is reduced in sodium and/or substantially sodium-free. Also provided are methods for using the solution.
    Type: Application
    Filed: July 7, 2016
    Publication date: March 14, 2019
    Applicant: LIFERAFT BIOSCIENCES
    Inventors: R. Martin Emanuele, William Hoye, John Arthur, Stewart Smith, Scott Stern
  • Poloxamer therapy for heart failure
    Patent number: 9757411
    Abstract: Provided methods of administering poloxamer 188 for treating heart failure by only a single short relatively high dose infusion, or by regimen that includes the single infusion followed by additional infusions at intervals of 1-4 weeks.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: September 12, 2017
    Assignee: Aires Pharmaceuticals, Inc.
    Inventors: R. Martin Emanuele, Santosh Vetticaden, Patrick Keran
  • POLOXAMER COMPOSITION FREE OF LONG CIRCULATING MATERIAL AND METHODS FOR PRODUCTION AND USES THEREOF
    Publication number: 20170002141
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Application
    Filed: July 11, 2016
    Publication date: January 5, 2017
    Applicant: MAST THERAPEUTICS, INC.
    Inventors: R. Martin EMANUELE, Mannarsamy BALASUBRAMANIAN, Stewart V. SMITH
  • DIURETIC INDUCED ALTERATIONS OF PLASMA VOLUME
    Publication number: 20160235781
    Abstract: Provided are uses of a poloxamer and methods of administering a poloxamer for treating hemo-concentration, such as hemo-concentration resulting from dehydration and/or diuresis in a subject. Administration of a poloxamer prevents, treats or otherwise reduces adverse effects of hemo-concentration, dehydration and/or diuresis.
    Type: Application
    Filed: October 16, 2014
    Publication date: August 18, 2016
    Applicant: MAST THERAPEUTICS, INC.
    Inventor: R. Martin EMANUELE
  • Poloxamer composition free of long circulating material and methods for production and uses thereof
    Patent number: 9403941
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: August 2, 2016
    Assignee: Mast Therapeutics, Inc.
    Inventors: R. Martin Emanuele, Mannarsamy Balasubramanian, Stewart V. Smith
  • POLOXAMER COMPOSITION FREE OF LONG CIRCULATING MATERIAL AND METHODS FOR PRODUCTION AND USES THEREOF
    Publication number: 20160002401
    Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 7, 2016
    Inventors: R. Martin EMANUELE, Mannarsamy BALASUBRAMANIAN
  • METHODS AND COMPOSITIONS FOR IMPROVING HEMOSTASIS
    Publication number: 20160000823
    Abstract: Provided are methods and uses of polyoxyethylene/polyoxypropylene copolymers (poloxamers) for treating bleeding and hemorrhage in animals, including human or veterinary subjects, and thus, treating hemostatic dysfunction, resulting from, for example, drug, disease-, trauma- or surgical-induced bleeding. Polyoxyethylene/polyoxypropylene copolymers improve hemostasis and aid in the control of bleeding. Methods for treating strokes using the polyoxyethylene/polyoxypropylene copolymers also are provided. Devices, products and compositions for treating or preventing hemostatic dysfunction are provided.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 7, 2016
    Inventors: R. Martin EMANUELE, Debra Hoppensteadt, Jawed Fareed
  • POLOXAMER THERAPY FOR HEART FAILURE
    Publication number: 20160000822
    Abstract: Provided methods of administering poloxamer 188 for treating heart failure by only a single short relatively high dose infusion, or by regimen that includes the single infusion followed by additional infusions at intervals of 1-4 weeks.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 7, 2016
    Inventors: R. Martin EMANUELE, Santosh Vetticaden, Patrick Keran