Patents by Inventor Martin G. Dunkel

Martin G. Dunkel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine nucleosides
    Patent number: 6369040
    Abstract: Novel 2- and 4-substituted pyrimidine nucleosides and oligonucleosides are provided, as are methods and intermediates useful in preparing same.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: April 9, 2002
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Oscar L. Acevedo, Martin G. Dunkel, Phillip Dan Cook
  • Pyrimidine nucleoside compounds and oligonucleoside compounds containing same
    Patent number: 6060592
    Abstract: Novel 2- and 4-substituted pyrimidine nucleosides and oligonucleosides are provided, as are methods and intermediates useful in preparing same. In preferred embodiments, one of the 2- and 4-substituents is .dbd.O, .dbd.NH, or .dbd.NH.sub.2.sup.+ and the other is Q, .dbd.C (R.sub.A)--Q, C(R.sub.A)(R.sub.B)--C(R.sub.C)(R.sub.D)--Q, C (R.sub.A).dbd.C(R.sub.C)--Q or C.tbd.C--Q, where R.sub.A, R.sub.B, R.sub.C and R.sub.D independently are H, SH, OH, NH.sub.2, or C.sub.1 -C.sub.20 alkyl, or one of (R.sub.A)(R.sub.B) or (R.sub.C)(R.sub.D) is .dbd.O, and Q is halogen, hydrogen, C.sub.1 -C.sub.20 alkyl, C.sub.1 -C.sub.20 alkylamine, C.sub.1 -C.sub.20 alkyl-N-phthalimide, C.sub.1 -C.sub.20 alkylimidazole, C.sub.1 -C.sub.20 alkylbis-imidazole, imidazole, bis-imidazole, amine, N-phthalimide, C.sub.2 -C.sub.20 alkenyl, C.sub.2 -C.sub.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: May 9, 2000
    Assignee: ISIS Pharmaceuticals, Inc.
    Inventors: Oscar L. Acevedo, Martin G. Dunkel, Phillip Dan Cook