Patents by Inventor Martin Geppert

Martin Geppert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mice overexpressing aspartyl protease 2 (ASP2)
    Patent number: 6958433
    Abstract: The present invention provides a recombinant DNA construct comprising a coding sequence encoding human ASP2 and a brain-specific calcium calmodulin kinase promoter sequence which is operably linked to the coding sequence. The present invention further provides a transgenic non-human animal whose genome incorporates a polynucleotide comprising a coding sequence which encodes the human ASP2 protein wherein the coding sequence is operably linked to a brain-specific calcium calmodulin kinase II promoter.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: October 25, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Martin Geppert, Alexander James Harper, Steve Mark Harrison, Haydn Prosser
  • Method of using animal models to predict adverse drug reactions
    Publication number: 20050005309
    Abstract: The invention relates generally to the process of target validation in the pharmaceutical industry. A process for validating molecular targets is disclosed.
    Type: Application
    Filed: October 20, 2003
    Publication date: January 6, 2005
    Inventors: Glenn Cantor, Martin Geppert
  • Method for generation of a random RNAi library and its application in cell-based screens
    Publication number: 20040152172
    Abstract: The present invention provides methods and compositions relating to inhibitory RNA.
    Type: Application
    Filed: September 5, 2003
    Publication date: August 5, 2004
    Inventor: Martin Geppert
  • Compounds
    Publication number: 20040154049
    Abstract: The present invention provides a recombinant DNA construct comprising a coding sequence encoding human ASP2 and a brain-specific calcium calmodulin kinase promoter sequence which is operably linked to the coding sequence. The present invention further provides a transgenic non-human animal whose genome incorporates a polynucleotide comprising a coding sequence which encodes the human ASP2 protein wherein said coding sequence is operably linked to a brain-specific calcium calmodulin kinase II promoter.
    Type: Application
    Filed: August 20, 2002
    Publication date: August 5, 2004
    Inventors: Martin Geppert, Alexander James Harper, Steve Mark Harrison, Haydn Prosser