Patents by Inventor Martin Gottlicher

Martin Gottlicher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Valproic acid and derivatives thereof as histone deacetylase inhibitors
    Publication number: 20070232696
    Abstract: The present invention relates to the use of the drug valproic acid and derivatives thereof as inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of those compounds for the manufacture of a medicament for the treatment of diseases which are associated with hypoacetylation of histones or in which induction of hyperacetylation has a beneficial effect for example by induction of differentiation and/or apoptosis in transformed cells.
    Type: Application
    Filed: January 17, 2007
    Publication date: October 4, 2007
    Inventors: Martin Gottlicher, Thorsten Heinzel, Bernd Groner, Peter Herrlich
  • Valproic acid and derivatives thereof as histone deacetylase inhibitors
    Patent number: 7265154
    Abstract: The present invention relates to the use of the drug valproic acid and derivatives thereof as inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of those compounds for the manufacture of a medicament for the treatment of diseases which are associated with hypoacetylation of histones or in which induction of hyperacetylation has a beneficial effect for example by induction of differentiation and/or apoptosis in transformed cells.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: September 4, 2007
    Assignee: Georg-Speyter-Haus Chemotherapeutisches Forschungsinstitut
    Inventors: Martin Göttlicher, Thorsten Heinzel, Bernd Groner, Peter Herrlich
  • Method for producing agents for treating tumor diseases and for immunosuppression
    Patent number: 6482610
    Abstract: The invention relates to a process for preparing agents which are suitable for treating tumour diseases or for immunosuppression, with target cells being treated with chemical compounds which bind to the Ah receptor of the target cells, the binding of the chemical compound(s) to the Ah receptor of the target cells being determined by measuring the expression, which is induced thereby, of a detector gene which is relevant for the effects of the chemical compound(s), and the chemical compound(s) which has/have been found in this way being used for preparing the agent(s).
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: November 19, 2002
    Assignee: Forschungszentrum Karlsruhe GmbH
    Inventors: Martin Göttlicher, Siva Kumar Kolluri, Carsten Weiss