Abstract: The invention relates to a method for scanning field correction at least of a laser scanner device (300), wherein the method comprises the following steps: —providing a scatter pattern element (30) on a processing plane (11), wherein the scatter pattern element (30) comprises at least one scatter region (31) which is arranged in a scatter pattern (M); —passing over or scanning at least one part of the scatter pattern element (30) on the processing plane (11) by means of a laser beam (12) of the at least one laser scanner device (300) along scanner coordinates (x, y, z), wherein the laser beam passes through at least one window (20), preferably protective glass, between a deflection unit (10) and the processing plane (11); —detecting scatter radiation (13) which can be generated by scattering and/or reflection of the laser beam (12) when passing over or scanning the at least one scatter region (31); —creating a contour diagram (K) by correlating the detected scatter radiation (13) with the scanner coordinates

Abstract: An electromechanical steering system may include a reduction gearbox where a worm gear is mounted in first and second bearings rotatably about a longitudinal axis. Rolling elements are disposed between inner and outer rings of the bearings. The inner rings are rotationally fixed on a shaft driven by the worm gear. A spring element is disposed between the inner ring of the second bearing and the worm gear. The spring element has an at least partially annular main body that when installed extends coaxially with the longitudinal axis. Spring arms in a circumferential direction are spaced apart from the longitudinal axis emanating from an external circumferential side of the main body. A first spring arm has a first leg that points away from the longitudinal axis and a second leg on which a free end is disposed, with the second leg running at least partially parallel to the longitudinal axis.

Abstract: A method for producing a photovoltaic solar cell, including the method steps: A. providing at least one solar cell precursor having at least one base and at least one emitter; B. providing a metal film on a back side of the solar cell precursor, so that the metal film is electrically conductively connected to the base or the emitter, the metal film being formed as an integral component of the back side contact and the solar cell being terminated on the back side. The at least one cell connection region on at least one side of the metal film overhangs the edge of the solar cell precursor by at least 1 mm, preferably by at least 3 mm.

Abstract: This application relates to non-human primate (NHP) induced pluripotent stem cell (IPSC)-derived hepatocytes, for example, Cynomolgus monkey (Macaca fascicularis) induced pluripotent stem cell-derived hepatocytes, and methods of producing the same. Moreover, this application relates to methods of using NHP IPSC-derived hepatocytes for drug screening, drug safety assessment and in models of infection.

Abstract: An electromechanical steering system may include a reduction gearbox where a worm gear is mounted in first and second bearings rotatably about a longitudinal axis. Rolling elements are disposed between inner and outer rings of the bearings. The inner rings are rotationally fixed on a shaft driven by the worm gear. A spring element is disposed between the inner ring of the second bearing and the worm gear. The spring element has an at least partially annular main body that when installed extends coaxially with the longitudinal axis. Spring arms in a circumferential direction are spaced apart from the longitudinal axis emanating from an external circumferential side of the main body. A first spring arm has a first leg that points away from the longitudinal axis and a second leg on which a free end is disposed, with the second leg running at least partially parallel to the longitudinal axis.

Abstract: A method for producing a photovoltaic solar cell, including the method steps: A. providing at least one solar cell precursor having at least one base and at least one emitter; B. providing a metal film on a back side of the solar cell precursor, so that the metal film is electrically conductively connected to the base or the emitter, the metal film being formed as an integral component of the back side contact and the solar cell being terminated on the back side. The at least one cell connection region on at least one side of the metal film overhangs the edge of the solar cell precursor by at least 1 mm, preferably by at least 3 mm.

Abstract: This application relates to a method for differentiating somatic cells into multi-competent neural crest cells based on linked steps of chemically defined medium inductions. Neural crest cells are able to differentiate into numerous cell types like Schwann cells, chondrocytes, smooth muscle cells or adipocytes.

Abstract: This application relates to a method for differentiating pluripotent stem cells (PSCs) into vascular bed cells. Moreover this application relates to a method for differentiating human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into vascular bed cells based on linked steps of chemically defined medium inductions.

Abstract: This application relates to non-human primate (NHP) induced pluripotent stem cell (IPSC)-derived hepatocytes and methods of producing the same. Moreover, this application relates to methods of using NHP IPSC-derived hepatocytes for drug screening, drug safety assessment and in models of infection.

Abstract: This application relates to a method for differentiating pluripotent stem cells (PSCs) into multi-competent renal precursor cells expressing Six2. These renal precursor cells are able to differentiate into fully functional and fully differentiated podocytes. Moreover this application relates to a method for differentiating human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into defined renal precursor cells expressing Six2 and podocytes based on linked steps of chemically defined medium inductions.

Abstract: This application relates to a method for differentiating somatic cells into multi-competent neural crest cells based on linked steps of chemically defined medium inductions. Neural crest cells are able to differentiate into numerous cell types like Schwann cells, chondrocytes, smooth muscle cells or adipocytes.

Abstract: This application relates to a method for converting somatic cells to Neural Stem Cells (NSCs). Moreover this application relates to a method for converting human fibroblasts, keratinocytes or adipocytes to neural stem cells based on linked steps of genes transduction and chemically defined medium induction.

Abstract: This application relates to a method for differentiating pluripotent stem cells (PSCs) into multi-competent renal precursor cells expressing Six2. These renal precursor cells are able to differentiate into fully functional and fully differentiated podocytes. Moreover this application relates to a method for differentiating human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into defined renal precursor cells expressing Six2 and podocytes based on linked steps of chemically defined medium inductions.

Abstract: This application relates to a method for converting somatic cells to Neural Stem Cells (NSCs). Moreover this application relates to a method for converting human fibroblasts, keratinocytes or adipocytes to neural stem cells based on linked steps of genes transduction and chemically defined medium induction.

Abstract: This application relates to a method for differentiating pluripotent stem cells (PSCs) into vascular bed cells. Moreover this application relates to a method for differentiating human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into vascular bed cells based on linked steps of chemically defined medium inductions.

Abstract: This application relates to a method for converting somatic cells to Neural Stem Cells (NSCs). Moreover this application relates to a method for converting human fibroblasts, keratinocytes or adipocytes to neural stem cells based on linked steps of genes transduction and chemically defined medium induction.

Abstract: A radiotherapy clinical treatment machine is described having a rotatable gantry and an imaging device with articulating robotic arms to provide variable positioning and clearance for radiation treatment applications. According to one aspect of the invention, a first and a second robotic arms are pivotally coupled to the rotatable gantry, allowing the robotic arms to maneuver independently from the rotatable gantry.

Abstract: This invention comprises cellular vaccines and methods of using them in cancer immunotherapy, particularly in humans. The vaccines comprise a source of tumor-associated antigen, and a cytokine-secreting cell line. Tumor antigen may be provided in the form of primary tumor cells, tumor cell lines or tumor extracts prepared from the subject. In certain embodiments of the invention, the cytokine-secreting line is a separate tumor line that is allogeneic to the patient and genetically altered so as to produce a cytokine at an elevated level. Exemplary cytokines are IL-4, GM-CSF, IL-2, TNF-?, and M-CSF in the secreted or membrane-bound form. In these embodiments, the cytokine-producing cells provide immunostimulation in trans to generate a specific immune response against the tumor antigen.

Abstract: This invention comprises cellular vaccines and methods of using them in cancer immunotherapy, particularly in humans. The vaccines comprise a source of tumor-associated antigen, and a cytokine-secreting cell line. Tumor antigen may be provided in the form of primary tumor cells, tumor cell lines or tumor extracts prepared from the subject. In certain embodiments of the invention, the cytokine-secreting line is a separate tumor line that is allogeneic to the patient and genetically altered so as to produce a cytokine at an elevated level. Exemplary cytokines are IL-4, GM-CSF, IL-2, TNF-?, and M-CSF in the secreted or membrane-bound form. In these embodiments, the cytokine-producing cells provide immunostimulation in trans to generate a specific immune response against the tumor antigen.

Abstract: The present invention relates to a fluorescently labeled growth hormone secretagogue which can be used for the identification of compounds capable of binding to growth hormone secretagogue receptors, in particular by high throughput screening.