Abstract: A method reduces the microbiological loading of container products made at least partially of at least one plastic material. As part of a first production process, a plastic granulate (29) is fed to an extruder device (19), which melts the granulate (29). As part of a subsequent production process, the melted granulate is forwarded onto a blow-molding, filling and sealing machine for obtaining the respective container product. At least in parts of the first production process, the plastic material undergoes at least one of the following treatment steps: high-energy radiation and/or plasma treatment and/or a gas having a sterilizing effect.

Abstract: A container of plastic material is produced using the blow, fill and seal method, with the filler material, enclosed by a container wall (15, 20) that can be autoclaved. At least one shape (19, 21, 23, 25, 29, 33) is provided in the container wall (15, 20) that ensures, despite a low relative air volume in the container, that when administering the filler material by infusion, the container wall (15, 20) collapses at least partially reducing the volume, without aeration of the container.

Abstract: A device for reducing the microbiological contaminants of container products made predominantly of plastics materials feeds a plastics granulate to an extruder assembly (19) that melts the granulate. The granulate is subsequently supplied to a form-fill-seal machine for producing a container product. A guide assembly (35) guides the plasticated plastic material from the extruder assembly (19) to the machine. At least one guide assembly (35) has at least one flow or channel guide (41) for the melted plastics material, so that microbiological contaminants are guided predominantly into the interior of the wall of the polymeric tube that interior is enclosed by regions of the plastic material that are less contaminated.

Abstract: A blow molding, filling and closing process and container product produced accordingly, in particular an ampoule product. A blow molding, filling and closing process for producing a filled and closed container product that can be stored as well, in particular in the form of an ampoule product which is formed from a plastic material and has a single-layer container wall or ampoule wall and which, during initial use, permits the withdrawal, in particular for an oral use of the product content, by opening at least one withdrawal opening for withdrawal purposes, is characterized in that plastic materials suitable for the process are selected which are tasteless and/or odorless or essentially tasteless and/or odorless in interaction with the contents of the container before and during use and which retain this tastelessness and/or odorlessness even after prolonged storage.

Abstract: A container consisting of plastic material that is produced using the blow, fill and seal method and the filler material of which, enclosed by a container wall (15, 20), can be autoclaved, is characterized in that at least one shaping means (19, 21, 23, 25, 29, 33) is provided in the container wall (15, 20), which ensures, despite a low relative air volume in the container, that when administering the filler material by infusion the container wall (15, 20) collapses at least partially reducing the volume, without aeration of the container.

Abstract: The invention relates to a method for reducing the microbiological loading of container products consisting at least partially of at least one plastic material, in which, as part of a first production process, a plastic granulate (29) is fed to an extruder device (19), which melts the granulate (29), which, as part of a further subsequent production process, is forwarded onto a blow¬molding, filling and sealing machine for obtaining the respective container product, characterised in that, at least in parts of the first production process, the respective used plastic material undergoes at least one of the following treatment steps: high-energy radiation and/or plasma treatment and/or a gas having a sterilizing effect.

Abstract: The invention relates to a device for reducing the microbiological contaminants of container products which consist predominantly of plastics materials. In said device a plastics granulate is fed to an extruder assembly (19) which melts the granulate, said granulate being subsequently supplied to a form fill seal machine for producing the relevant container product. The device also comprises a guide assembly (35) for the targeted guidance of the plasticated plastics material from the extruder assembly (19) to said machine. The device is characterised in that at least one guide assembly (35) has at least one flow or channel guide (41) for the melted plastics material, so that microbiological contaminants are guided predominantly into the interior of the wall of the polymeric tube, said interior being enclosed by regions of the plastics material that are less contaminated.

Abstract: The invention relates to a plastic container product, in particular produced by the blow-molding, filling, and sealing method, having a container wall which can be pierced by means of a cannula in predefinable areas for the purpose of access to the container content. Said plastic container product is characterized in that, in order to avoid punched parts which arise when the container wall is pierced with a cannula, the mathematical product of the container wall thickness in the piercing area and the tensile modulus of the plastic material to ISO 527 is less than 400 MPa·mm, in particular preferably less than 300 MPa·mm.

Abstract: The invention relates to a plastic container product, in particular produced by the blow-molding, filling, and sealing method, having a container wall which can be pierced by means of a cannula in predefinable areas for the purpose of access to the container content. Said plastic container product is characterized in that, in order to avoid punched parts which arise when the container wall is pierced with a cannula, the mathematical product of the container wall thickness in the piercing area and the tensile modulus of the plastic material to ISO 527 is less than 400 MPa·mm, in particular preferably less than 300 MPa·mm.