Patents by Inventor Martin H. Osterhout

Martin H. Osterhout has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
    Patent number: 6410792
    Abstract: Amide derivatives and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 25, 2002
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • NPY5 receptor antagonists and methods for using same
    Patent number: 6245817
    Abstract: &agr;-alkoxy and &agr;-thioalkoxyamide compositions and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 12, 2001
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • Substituted biphenyls
    Patent number: 6218431
    Abstract: Substituted biphenyls having glucagon receptor antagonistic activity. Claimed compounds have the formula wherein R1a and R1b independently represent (C1-C6) alkyl; R2 represents (C1-C10) alkyl or substituted (C1-C10) alkyl wherein the substituents are independently from 1 to 3 of —SR7; R7 represents phenyl, or substituted phenyl wherein the substituents are independently 1-5 of halogen, trifluoromethyl, (C1-C6) alkyl, (C1-C6) alkoxy, nitro, cyano, or hydroxyl; R3 represents substituted (C1-C6) alkyl wherein the substituents are 1-2 hydroxyl groups; G represents a substituent selected from the group consisting of halogen, (C1-C6) alkyl, and OR4 wherein R4 is H or (C1-C6) alkyl; and y is 0 or an integer of 1-3. Pharmaceutical compositions containing such compounds and methods of treatment of glucagon-mediated conditions by administering such compounds are also claimed.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: April 17, 2001
    Assignees: Bayer Corporation, Bayer Aktiengesellschaft
    Inventors: William R. Schoen, Gaetan H. Ladouceur, James H. Cook, II, Timothy G. Lease, Donald J. Wolanin, Richard H. Kramss, Donald L. Hertzog, Martin H. Osterhout
  • Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
    Patent number: 6048900
    Abstract: Amide derivatives and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: April 11, 2000
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • NPY5 receptor antagonists and methods for using same
    Patent number: 5939462
    Abstract: .alpha.-alkoxy and .alpha.-thioalkoxyamide compositions and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: August 17, 1999
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout