Abstract: The invention features methods and systems to monitor changes in the magnitude of attentional disturbance and the magnitude of motor activity disturbance in a subject. The invention also features methods and systems for determining a subject's degree of concordance with individuals having an attentional disorder versus individuals not having an attentional disorder. The methods and systems of the invention can enable clinicians and consumers to ascertain both the severity of an attentional disorder as well as how much an individual changes over time, or with therapy.

Abstract: The invention features methods and systems for the diagnosis of ADHD and related disorders. The methods and systems of the invention can also be used to ascertain how much benefit an individual would derive from a particular therapy.

Abstract: The invention features methods and systems for the diagnosis of ADHD and related disorders. The methods and systems of the invention can also be used to ascertain how much benefit an individual would derive from a particular therapy.

Abstract: The invention features methods and systems for the diagnosis of ADHD and related disorders. The methods and systems of the invention can also be used to ascertain how much benefit an individual would derive from a particular therapy.

Abstract: Provided are methods for assessing the attentional state of a subject by scoring the subject's response to auditory stimuli. The methods can be used to diagnose psychological and behavioral disorders, such as attention deficit disorder or hyperkinetic disorder.

Abstract: The invention features methods and systems for the diagnosis of ADHD and related disorders. The methods and systems of the invention can also be used to ascertain how much benefit an individual would derive from a particular therapy. One method of diagnosing ADHD or a related disorder in a subject comprising the steps of: (i) providing motor activity data having been collected by using a motion analysis device to record movements of said subject; (ii) analyzing said motor activity data to calculate a value for a measure of inhibitory control in said subject; and (iii) on the basis of said value, diagnosing said subject.

Abstract: Provided are methods for diagnosing the presence, type, or severity of a dementia in a human subject. The methods involve using a computer-based system to assess impairment of certain cognitive and motor functions that are indicative of Alzheimer's disease and other forms of dementia.

Abstract: The invention features methods and systems to monitor changes in the magnitude of attentional disturbance and the magnitude of motor activity disturbance in a subject. The invention also features methods and systems for determining a subject's degree of concordance with individuals having an attentional disorder versus individuals not having an attentional disorder. The methods and systems of the invention can enable clinicians and consumers to ascertain both the severity of an attentional disorder as well as how much an individual changes over time, or with therapy.

Abstract: The invention provides methods for determining shifts in the attentional state of a subject. These methods are useful for diagnosing subjects with a psychological or behavioral disorder. The invention also features methods for determining the effect of a therapy on the overall attentional state and shifts in the attentional state of a subject.

Abstract: The invention features corticosteroids conjugated to either a charged group or a bulky group in a manner that resists in vivo cleavage, the resulting conjugate is a peripherally acting steroid with reduced activity in the central nervous system. The invention provides a method for treating a patient having an inflammatory disease by administering to the patient a corticosteroid conjugate.

Abstract: Provided are methods for assessing the attentional state of a subject by scoring the subject's response to auditory stimuli. The methods can be used to diagnose psychological and behavioral disorders, such as attention deficit disorder or hyperkinetic disorder.

Abstract: The invention provides methods for determining the attentional state of a subject. These methods are useful for diagnosing subjects with a psychological or behavioral disorder. The invention also features methods for determining the effect of a therapy on the attentional state of a subject.

Abstract: Provided are methods for diagnosing the presence, type, or severity of akathisia in a human subject. The methods involve using a computer-based system to assess impairment of certain cognitive and motor functions that are indicative of akathisia.

Abstract: A method for treating attention deficit/hyperactivity disorder (ADHD) includes performing an objective ADHD behavioral assay for a patient, administering a drug to the patient at varying doses, and performing an fMRI on the patient for the varying drug doses to determine an optimal dosage for the patient. The method can further include performing a further objective ADHD behavioral assay after the drug administration.

Abstract: The invention provides methods for determining shifts in the attentional state of a subject. These methods are useful for diagnosing subjects with a psychological or behavioral disorder. The invention also features methods for determining the effect of a therapy on the overall attentional state and shifts in the attentional state of a subject.

Abstract: The invention features corticosteroids conjugated to either a charged group or a bulky group in a manner that resists in vivo cleavage, the resulting conjugate is a peripherally acting steroid with reduced activity in the central nervous system. The invention provides a method for treating a patient having an inflammatory disease by administering to the patient a corticosteroid conjugate.

Abstract: The invention provides methods for determining shifts in the attentional state of a subject. These methods are useful for diagnosing subjects with a psychological or behavioral disorder. The invention also features methods for determining the effect of a therapy on the overall attentional state and shifts in the attentional state of a subject.

Abstract: Provided are methods for diagnosing the presence, type, or severity of akathisia in a human subject. The methods involve using a computer-based system to assess impairment of certain cognitive and motor functions that are indicative of akathisia.

Abstract: Provided are methods for diagnosing the presence, type, or severity of a dementia in a human subject. The methods involve using a computer-based system to assess impairment of certain cognitive and motor functions that are indicative of Alzheimer's disease and other forms of dementia.

Abstract: The invention provides methods for enhancing the differential diagnosis of attention deficit disorder (ADHD) versus anxiety disorder in a human patient undergoing testing for ADHD.