Abstract: The eye is illuminated by a variable laser light source with a measurement range corresponding to the eye length, wherein the focus of the laser beam in the eye can be shifted laterally and/or axially by an adjustment mechanism, and the light fractions back-scattered from the sample are captured via an interferometer by a data acquisition unit and forwarded to a data processing unit. In the data processing unit, an OCT whole-eye scan is combined with at least one or several further overlapping tomographic part-eye or whole-eye scans. Reference information is used to register the first whole-eye scan with the further part-eye or whole-eye scans, and the combined whole-eye scan is evaluated and/or displayed on a user surface.

Abstract: A method and devices for detecting deposits, in particular amyloid plaques, in the eye, in particular in the human eye. The subject is an optical method for detecting deposits, in particular ?-amyloid, in the retina, which is locally resolved and wherein the local resolution is better than the layer thickness of individual layers of the retina. The invention includes a device for optically detecting ?-amyloid in the retina, which generates a locally resolved image of the retina and wherein the local resolution is better than the layer thickness of individual layers of the retina.

Abstract: Asphalt binder compositions are provided comprising asphalt and a polymer blend, wherein the polymer blend comprises oxidized high density polyethylene and another polymer chosen from: maleated polypropylene, polyethylene homopolymer, high crystallinity polyethylene, and combinations thereof. Also provided are paving and roofing materials comprising the aforesaid asphalt binder compositions and an aggregate material. Methods for making and using the asphalt binder compositions are also provided.

Abstract: Asphalt compositions for roofing applications are provided, as well as filled asphalt material comprising the asphalt compositions and methods for making asphalt compositions and filled asphalt material. More particularly, the asphalt compositions comprise non-oxidized base asphalt; and a low molecular weight polyolefin present in an amount of from about 0.5 to about 15 wt % based on the total weight of the asphalt composition. The asphalt composition has a softening point from about 87.8 to about 160° C. (about 190 to about 320° F.), a penetration of greater than 12 deci-millimeters @ 25° C., as well as improved stain resistance and heat resistance.

Abstract: A method for Determining at Least One Parameter for Diagnosis or Risk Assessment of a Disease, including AMD. The distribution of the macular pigment MP of an eye and at least one area A whose bordering line corresponds to a constant optical density MPD and/or concentration MPC of MP is determined by an analysis unit. The bordering line is subjected to a quantitative shape description. At least one parameter DP, suitable for diagnosing a disease and/or the risk of a disease is derived from the quantitative shape description of the bordering line of the areas A. The method is provided for diagnosis or risk assessment but may also be used in the context of treatment of macular pigment deficiency phenomena to select the required supplements. This method, based on the determination of the fractal dimension, is also suitable for diagnosing other diseases such as edemas, actinomycoses, atrophies or lesions.

Abstract: A fundus camera with an OCT measurement module, in which, after the focusing objective, a mirror switches the light to be detected either to the OCT measurement module or an image detector. This design also renders it possible to carry out a method for improved focusing in order to improve the recording quality of the individual modalities. Furthermore, the multimodal measuring instrument distinguishes itself by an operating concept according to the invention. Such combination instruments are advantageous in that, as a result of the reduction from two instruments to one, less space is required than in the case of two separate instruments. Furthermore, reseating of the patient is avoided if recordings or measurements of different modalities should be made for one and the same patient, as a result of which the procedures in the medical practices and clinics can be influenced positively.

Abstract: A short coherence interferometer for measuring several axially spaced-apart regions of a sample, especially of an eye, which has a measuring optical path, through which the measuring radiation falls on the sample, a tunable interferometer for the axial, relative retardation of parts of the radiation, wherein the axial relative retardation is assigned to the axial spacing of the regions and a detector for producing an interference signal from interfering measurement radiation, scattered or reflected back from the sample as sample radiation. The tunable interferometer divides the sample radiation into two parts, which are axially relatively retarded and superimposed so as to interfere. During the superimposition, the tunable interferometer forms individual radiations, which represent quadrature components of the sample radiation, and the detector detects the individual radiations.

Abstract: A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. The swept-source OCT scan detects the whole eye over the length thereof so that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized.

Abstract: A system for determining the surface shape of the cornea of an eye by analyzing the reflection of a spatially distributed ring pattern. The system includes an element for generating a ring pattern, an illuminating unit, an image capturing unit, and a control and analyzing unit. The element for generating rings is a fresneled axicon with annular structures of different radii. Furthermore, an optical element for illuminating the entire surface of the fresneled axicon with plane waves and an optical element for separating the illuminating and detecting beam path are arranged between the illuminating unit and the fresneled axicon. Furthermore, the image capturing unit consisting of an imaging system and an image sensor is designed for a telecentric distance-independent image detection.

Abstract: Asphalt binder compositions are provided comprising asphalt and a polymer blend, wherein the polymer blend comprises oxidized high density polyethylene and another polymer chosen from: maleated polypropylene, polyethylene homopolymer, high crystallinity polyethylene, and combinations thereof. Also provided are paving and roofing materials comprising the aforesaid asphalt binder compositions and an aggregate material. Methods for making and using the asphalt binder compositions are also provided.

Abstract: A device for swept-source optical coherence domain reflectometry (SS OCDR) on moveable samples, particularly human eyes, for obtaining A-scans, having a measuring range according to the sample length and having a laser light source which can be adjusted by a main wave number k0 and at least one receiver for the light dissipated from the sample, wherein the sample is illuminated on the sample surface by a measurement beam having a diameter D by way of a coupling device. The light source has a spectral line width of ?k<168 m?1 and the adjustment of the light source is carried out in ?<44 s/(D*k0).

Abstract: A line scan imager is used to determine the motion of a subject. Each line of image data from the line scan imager is compared with a reference image. The location of a matching line in the reference image reveals the displacement of the subject. The current subject displacement can be determined based on each line of image data. The resulting displacement information can be used to correctly place other optical beams on the subject. The method can be applied to tracking the human eye to facilitate measurement, imaging, or treatment with a beam of optical radiation.

Abstract: Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.

Abstract: Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.

Abstract: An ophthalmological measuring system, for obtaining biometric data of an eye, provided with the necessary calibration and check devices for monitoring the functionality and the calibration status. The ophthalmological measuring system includes an illumination source for illuminating an eye with light and with a sensor for recording and analyzing back-scattered or reflected light components and a controller. At least one calibration and check system integrated in the ophthalmological measuring system for monitoring the functional and calibration status is provided. A device is also provided which houses the calibration and test structures and which reads off the individual physical data therefrom by an interface. The ophthalmological measuring system is in particular provided for determining biometrical data but can also be used for ophthalmological, dermatological or other devices which require calibration and/or functional checking at regular intervals.

Abstract: Selection of an appropriate intraocular lens (IOL) and/or the applicable surgical parameters for optimizing the results of refractive procedures on the eye. Features of the IOL are crucial for the selection and/or adjustment of the optimal IOL, but so is the IOL selection method (and parameters) from a surgical perspective. For the method, corresponding output parameters are determined from predetermined, estimated, or measured input parameters and/or their mean values, wherein at least two input parameters are varied with one another and which have at least one input parameter as a distribution function. The resulting function is optimized by means of corresponding target values and the determined distribution function of one or more output parameters is used as a decision aid. The present solution is used for selecting an appropriate IOL and/or the applicable surgical parameters and is applicable in the field of eye surgery for implanting IOLs.

Abstract: Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.

Abstract: Selection of an appropriate intraocular lens (IOL) and/or the applicable surgical parameters for optimizing the results of refractive procedures on the eye. Features of the IOL are crucial for the selection and/or adjustment of the optimal IOL, but so is the IOL selection method (and parameters) from a surgical perspective. For the method, corresponding output parameters are determined from predetermined, estimated, or measured input parameters and/or their mean values, wherein at least two input parameters are varied with one another and which have at least one input parameter as a distribution function. The resulting function is optimized by means of corresponding target values and the determined distribution function of one or more output parameters is used as a decision aid. The present solution is used for selecting an appropriate IOL and/or the applicable surgical parameters and is applicable in the field of eye surgery for implanting IOLs.

Abstract: An ophthalmological measuring system for determining distances and/or for tomographic imaging of ocular structures, based on an OCT method. The measuring system includes a light source with a spectral centroid (?), an interferometric measuring device, a scanner system, which in addition to the lateral deflection of the sample beam also has axial modulations with a frequency (f) in the sample arm, and a control and evaluation unit. The scanner performs a lateral, two-dimensional deflection of the sample beam with the aid of one or even two separate mirror elements and can in particular have axial modulation amplitudes zM>>?/2. The system can also be used for scanner systems in other fields that use an OCT method, in particular a swept-source OCT method.

Abstract: A device for swept-source optical coherence domain reflectometry (SS OCDR) on moveable samples, particularly human eyes, for obtaining A-scans, having a measuring range according to the sample length and having a laser light source which can be adjusted by a main wave number k0 and at least one receiver for the light dissipated from the sample, wherein the sample is illuminated on the sample surface by a measurement beam having a diameter D by way of a coupling device. The light source has a spectral line width of ?k<168 m?1 and the adjustment of the light source is carried out in ?<44 s/(D*k0).