Patents by Inventor Martin Hosking

Martin Hosking has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cells having solid tumor targeting backbone and use thereof
    Patent number: 12203098
    Abstract: Provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered iPSCs. Also provided are derivative cells having stable and functional genome editing that delivers improved or enhanced therapeutic effects. Further provided are therapeutic compositions and the use thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: January 21, 2025
    Assignee: FATE THERAPEUTICS, INC.
    Inventors: Bahram Valamehr, Tom Tong Lee, Martin Hosking, Eigen Peralta, Chia-Wei Chang
  • Chimeric antigen receptor for tumor targeting
    Patent number: 12122846
    Abstract: Provided are chimeric antigen receptors (CAR) specific to a selected tumor antigen. Also provided are structure designs and function profiles of provided CAR candidates.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: October 22, 2024
    Assignees: FATE THERAPEUTICS, INC., ONO PHARMACEUTICAL CO., LTD.
    Inventors: Bahram Valamehr, Tom Tong Lee, Martin Hosking, Susumu Yamamoto, Tatsuo Maeda
  • COMPOSITION AND METHODS FOR INDUCING MYELOID SUPPRESSIVE CELLS AND USE THEREOF
    Publication number: 20240158747
    Abstract: Compositions and methods for manufacturing induced immune regulatory cells comprising induced myeloid suppressive cells including MDSCs (myeloid-derived suppressor cells), dendritic cells, macrophages, and subpopulations thereof are provided. Also provided are methods and compositions for further modifying and modulating the induced immune regulatory cells to achieve enhanced therapeutic potential in treating autoimmune disorders, hematological malignancies, solid tumors, viral infections, neurodegenerative disorders, inflammatory conditions, or GvHD.
    Type: Application
    Filed: November 3, 2023
    Publication date: May 16, 2024
    Inventors: Philippe A. Parone, Robert S. Tacke, Bahram Valamehr, Daniel Shoemaker, Martin Hosking, Lisa Guerrettaz
  • Composition and methods for inducing myeloid suppressive cells and use thereof
    Patent number: 11851677
    Abstract: Compositions and methods for manufacturing induced immune regulatory cells comprising induced myeloid suppressive cells including MDSCs (myeloid-derived suppressor cells), dendritic cells, macrophages, and subpopulations thereof are provided. Also provided are methods and compositions for further modifying and modulating the induced immune regulatory cells to achieve enhanced therapeutic potential in treating autoimmune disorders, hematological malignancies, solid tumors, viral infections, neurodegenerative disorders, inflammatory conditions, or GvHD.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: December 26, 2023
    Inventors: Philippe A. Parone, Robert S. Tacke, Bahram Valamehr, Daniel Shoemaker, Martin Hosking, Lisa Guerrettaz
  • COMPOSITION AND METHODS FOR INDUCING MYELOID SUPPRESSIVE CELLS AND USE THEREOF
    Publication number: 20200102536
    Abstract: Compositions and methods for manufacturing induced immune regulatory cells comprising induced myeloid suppressive cells including MDSCs (myeloid-derived suppressor cells), dendritic cells, macrophages, and subpopulations thereof are provided. Also provided are methods and compositions for further modifying and modulating the induced immune regulatory cells to achieve enhanced therapeutic potential in treating autoimmune disorders, hematological malignancies, solid tumors, viral infections, neurodegenerative disorders, inflammatory conditions, or GvHD.
    Type: Application
    Filed: June 13, 2018
    Publication date: April 2, 2020
    Inventors: Philippe A. Parone, Robert S. Tacke, Bahram Valamehr, Daniel Shoemaker, Martin Hosking, Lisa Guerrettaz