Abstract: The present invention concerns the use of aprotic polar solvents, water, and an ionization stabilizing agent to prepare device compatible stable therapeutic formulations by dissolving a therapeutic agent (active ingredient) in an aprotic polar solvent system that can then be used with various devices (e.g., pumps, infusion sets) for administration of the formulation. In certain embodiments, the invention is directed to formulations comprising one or more therapeutic agents, as well as methods of making such formulations, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system, such as a DMSO/water admixture, comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula

Abstract: Systems and methods are described herein to control brightness based on image content or other inputs to a display system. A dual-control system may integrate both slow control operations and fast control operations into a cohesive brightness management system. By using both shorter-term (e.g., fast control) and longer-term (e.g., slow control) brightness adjustment operations, the electronic device may quickly respond to high luminance and high brightness situations that may cause burn-in into the display, image artifacts, or other damage. Responding quickly to these high consumption situations may prevent damage or perceivable upset to an ongoing process, among other benefits.

Abstract: A cortical malformation identification method includes quantitatively evaluating, using a processor of a computer that includes the processor and a memory, digital image data from a magnetic resonance imaging (MRI) scan on a cerebral cortex to produce quantified scan data. The method also includes automatically detecting a cortical malformation based on the quantified scan data. An image of the cerebral cortex may be color-coded so that the cortical malformation is shown in a different color than the remainder of the cerebral cortex in the image, based on the quantified scan data. Additionally or alternatively, a 3-dimensional representation of the cerebral cortex may be mapped to the quantified scan data to produce a mapped image of the cerebral cortex including the detected cortical malformation.

Abstract: Systems and methods for account data association with voice interface devices are disclosed. For example, when a host user/primary user and guest user have consented for account data to be associated with the primary user's devices, a request to associate the account data may be received. Voice and device-based authentication may be performed to confirm the identity of the guest user and the guest user's account data may be associated with the primary user's devices. During a guest session, voice recognition may be utilized to determine if a given user utterance is from the guest user or the primary user, and actions may be performed by the voice interface device accordingly.

Abstract: Retail support methods are described. An example retail support method includes the steps: obtaining attributes associated with a plurality of items; organizing the attributes such that one or more of the attributes is grouped within a class having a class identifier; providing an interface that displays one or more of the class identifiers and provides a user interface element for selecting one or more of the class identifiers; receiving data relating to a selection of the class identifiers; providing another interface that displays one or more of the items and provides a second user interface element for creating a selected subset; receiving data relating to the selected subset; providing another interface that displays the selected subset, the attributes associated with the selected subset, and provides a third user interface element to submit a request to evaluate one or more items; and making the one or more items available for evaluation.

Abstract: Radiation scanning systems providing multiple views of an object in different planes and a reconstruction algorithm for reconstructing quasi-three-dimensional images from a limited number of views. A system may include bend magnets to direct accelerated charged particles to multiple targets in different viewing locations. Another system collimates radiation generated by a plurality of radiation sources into multiple beams for scanning an object at multiple angles. The object may be a cargo container, for example. The reconstruction algorithm uses an optimization algorithm and imaging and feasibility models to reconstruct quasi-three-dimensional images from the limited number of views.

Abstract: Radiation scanning systems providing multiple views of an object in different planes and a reconstruction algorithm for reconstructing quasi-three-dimensional images from a limited number of views. A system may include bend magnets to direct accelerated charged particles to multiple targets in different viewing locations. Another system collimates radiation generated by a plurality of radiation sources into multiple beams for scanning an object at multiple angles. The object may be a cargo container, for example. The reconstruction algorithm uses an optimization algorithm and imaging and feasibility models to reconstruct quasi-three-dimensional images from the limited number of views.

Abstract: An array tester (10) characterizes individual ones (111) of a semiconductor devices of an array (11) based on polarization-resolving an optical far-field measurement of the individual chips (111) as a function of angular position. Two pairs of TM and TE detectors (41a-b and 42a-b) or one pair displaceable by ninety degrees, move in vertical and horizontal arc paths or fixed around a fixed position of a selected device of an array to sample the far-fields.

Abstract: The present invention is directed to a method and system for providing a three-level current scheme to a semiconductor laser to control beam wavelength and laser temperature. A first current is received into a gain section of the semiconductor laser and at least one other current is received into a DBR and/or phase section of the semiconductor laser. This other current(s) is pulse-width modulated based upon a required temperature value. An output beam is generated by the semiconductor laser based upon the received first current and the received pulse-width modulated current(s).

Abstract: Both a system and method are provided for modulating the intensity of an output beam generated by semiconductor laser. The exemplary system includes a source of pulsating current connected to the laser that generates a pulsating beam of laser light, an external modulator having an input that receives the pulsating beam, and an output controlled by pulsating control signal, wherein the output beam transmitted by the external modulator output is modulated by changing a relative phase angle between the pulsating current powering the laser, and the control signal of the external modulator over time. The external modulator may be an intensity-type modulator whose output is controlled by a gate signal having a constant phase, and the source of pulsating current powering the laser may be variable phase in order to modulate the output beam with an external modulator having a simple structure.

Abstract: The present invention is directed to a method and system for providing phase modulated current to a semiconductor laser to control beam wavelength. A first current is received into a gain portion of the semiconductor laser and a second current is received into a DBR portion of the semiconductor laser. The second current is phase modulated based upon a required intensity value. An output beam is generated by the semiconductor laser based upon the received first current and the received second current.

Abstract: An array tester (10) characterizes individual ones (111) of a semiconductor devices of an array (11) based on polarization-resolving an optical far-field measurement of the individual chips (111) as a function of angular position. Two pairs of TM and TE detectors (41a-b and 42a-b) or one pair displaceable by ninety degrees, move in vertical and horizontal arc paths or fixed around a fixed position of a selected device of an array to sample the far-fields.

Abstract: A tester (10) for characterizing individual ones (111) of a semiconductor laser devices of a laser bar (11) includes a holder (12) for securing the laser bar (11) in a fixed position. For moving in at least one relative direction (21, 22, 23) with respect to the laser bar (11), a movable measurement system (16) is provided for characterizing the individual ones (111) of the semiconductor laser devices as a function of the at least one relative direction (21, 22, 23).

Abstract: A tester for characterizing individual ones of a semiconductor laser devices of a laser bar includes a holder for securing the laser bar in a fixed position. For moving in at least one relative direction with respect to the laser bar, a movable measurement system is provided for characterizing the individual ones of the semiconductor laser devices as a function of the at least one relative direction.