Abstract: An implant in accordance with an embodiment of the present technology includes proximal and distal end portions spaced apart from one another along a longitudinal axis and configured to be deployed at first and second airways, respectively, of a bronchial tree, the second airway being of a greater generation than the first airway. The implant includes a wire extending along a wire path within a tubular region coaxially aligned with the longitudinal axis. The wire includes first and second legs alternatingly disposed along the wire path and extending distally and proximally, respectively, in a circumferential direction about the longitudinal axis. The implant is configured to transition from a low-profile delivery state to an expanded deployed state at a treatment location and to allow mucociliary clearance from immediately distal to the implant to immediately proximal to the implant while the in deployed at the treatment location.

Abstract: There is provided a holder (300) for an inhaler article (200), the holder (300) comprising an inhalation volume estimator (350) and an air flow passage (322). The inhalation volume estimator (350) comprises a turbine (352) and an indicator coupled to the turbine (352) for indicating inhalation volume information relating to a volume of an air flow through the air flow passage (322). In use, the turbine (352) is configured to rotate in response to air flow through the air flow passage (322) and alter the inhalation volume information indicated by the indicator. An inhalation system (100) comprising the holder (300) is also provided.

Abstract: In general, the disclosure describes techniques for obtaining, by a computing system, a content item and a purported source for the content item, wherein the content item may include multimodal data. The techniques may further include generating, by the computing system, a plurality of modality feature vectors representative of the multimodal data, wherein each of the generated modality feature vectors has a different, corresponding modality feature. The techniques may further include mapping, by the computing system, the generated modality feature vectors based on a statistical distribution associated with the purported source. The techniques may further include determining, by the computing system, a score based on the mapping. The techniques may further include outputting, by the computing system and based on the score, an indication of whether the content item originated from the purported source.

Abstract: A multifunctional network switch for use in a process-controlling automation system, comprises a control unit, a plurality of ports, and a storage device that is adapted to store a first program for executing a network switch functionality and furthermore a second program for executing a control device functionality and/or a third program for executing a router functionality. The control unit is configured to execute a network switch functionality by running the first program and furthermore a control device functionality by running the second program and/or a router functionality by running the third program.

Abstract: Embodiments of the present disclosure generally relates to a coupling for coupling an external hearing device with an abutment of a bone anchored hearing system. The disclosure more particularly relates to a coupling for coupling an external hearing device with an abutment of a bone anchored hearing system, the coupling including: at least two coupling arms for establishing a connection to the abutment of the bone anchored hearing system. The disclosure further relates to a coupling assembly for coupling an external hearing device with an abutment of a bone anchored hearing system and a bone anchored hearing system.

Abstract: A method and system are disclosed for providing electrical power from a utility electric grid to a fracturing operation, and an electrically powered fracturing system. A mobile substation includes at least two transformer units that are operatively coupled to the utility electric grid in a parallel orientation, wherein the transformer units are capable of receiving power from the utility electric grid and stepping down the power for delivery to a switchgear. An electric motor is operatively coupled to a hydraulic fracturing pump and operatively controlled by a variable frequency drive. At least one open air relay cable is operatively coupled between the switchgear and the electric motor and capable of delivering power to the electric motor.

Abstract: Exemplary aspects involve a data-communications apparatus or system communicate over a broadband network with a plurality of remotely-located data-communications circuits respectively associated with a plurality of remotely-situated client entities. The system includes data-communications platform (e.g., UC-CC) that processes incoming data-communication interactions including different types of digitally-represented communications among which are incoming call, and that is integrated with a memory circuit including a database of information sets. Each of the information sets includes experience data corresponding to past incoming data-communication interactions processed by the platform, and with aggregated and organized data based on data collected in previous incoming interactions.

Abstract: A method for acquiring a characteristic curve of a PV generator is disclosed. In a power generation installation, an output side of each PV generator is connected via an assigned DC-DC converter, in parallel to a DC link as the input element of a DC-AC converter. The method includes reducing a cumulative output power of those DC-DC converters for which the associated PV generators are not intended for acquiring the characteristic curve during the acquisition of the characteristic curve of the PV generator to be scanned to ensure that the sum of the reduced cumulative output power and of the expected maximum power of the PV generator to be scanned does not exceed a nominal power of the DC-AC converter, and subsequently acquiring the characteristic curve of the PV generator to be scanned.

Abstract: The present disclosure provides apparatuses and computer readable media for measuring sub-epidermal moisture in patients to determine damaged tissue for clinical intervention. The present disclosure also provides methods for determining damaged tissue.

Abstract: dsRNAi oligonucleotides can be used in methods for the treatment of NASH, preferably the advanced fibrotic and/or cirrhotic stages thereof, using dosage regimens comprising a loading phase followed by a maintenance phase.

Abstract: An apparatus or process supplies a controlled stream of gas in a laminar flow to provide a laser beam permeable barrier in a plane between laser material processing byproducts and a final laser focusing optical element to separate a contaminated environment and a clean environment without directing gas towards the processing point of the laser. The stream of gas may be directed towards a filter by a vacuum source such as a fan. The vacuum source may be sized to draw in more gas than the stream of gas.

Abstract: The present invention relates to the use of hypoxia-inducible factor (HIF) inhibitors in cancer immunotherapy. Specifically, the disclosure provides methods of treating a cancer in a subject in need of cancer immunotherapy, comprising administering a HIF-1a inhibitor to the subject and a second cancer immunotherapeutic agent to the subject, wherein the HIF-1a inhibitor comprising echinomycin, and wherein the second cancer immunotherapeutic agent comprising an anti-CTLA-4 antibody including Ipilimumab or Tremelimumab.

Abstract: An arrangement for laser treatment of vitreous floaters. The arrangement for laser vitreolysis of an eye includes an OCDR system, a laser system having a deflection unit, optical elements that couple the OCDR system and the laser system, a display unit and a central control and operating unit. The OCDR system is configured to localize the position of a floater along the optical axis of the OCDR system. The laser system is configured to destroy the floaters by application of laser pulses, and the central control and operating unit is configured to focus the laser system onto the position of the floater and to activate it, in particular when the position of the laser focus and the floater match in a sufficient manner. The present invention relates to an arrangement for the gentle, low risk and painless laser treatment of vitreous floaters, which allows a partially or fully automated therapy.

Abstract: An earpad comprising one or more acoustic resonators coupled to a contact face of the earpad that is configured to interface with a user's head, the acoustic resonators being configured to attenuate leakage of parasitic sound.

Abstract: A dental model gripping system can include a dental model and a dental model gripper. The dental model can include a replica set of teeth and a flat bottom surface there beneath that can include first and second vertical openings spaced apart by an opening distance. The dental model gripper can have a flat top surface and first and second pins extending vertically therethrough that can slide toward and away from each other. The first and second pins can be slid to an engaging position where they are spaced apart by the opening distance and are insertable into the vertical openings of the dental model, can be slid away from each other to a gripping position while inserted into the vertical openings, and can press against internal surfaces within the vertical openings to grip firmly the bottom surface of the dental model against the top surface of the dental model gripper.

Abstract: An interlocking mechanism for a seat and a back of a chair is provided. A seat body and a chair chassis are pivotally connected, and a pad plate is pivotally connected with the seat body. Thereby the pad plate is moved around a pivotal connection between itself and the seat body when users sit on the pad plate. While a front side of the pad plate is moved downward, it is inclined to an angle slowly by a pad spring connected with the pad plate. When the use is leaning on the chair back connected with the seat body, the seat body is moved backward with a pivotal connection between itself and the chair chassis. The pivotal connection between the seat body and the pad plate can push the pad plate upward so that the seat body is inclined with the chair back and the user sits more comfortably.

Abstract: A heart valve leaflet replacement system for a diseased heart valve including a replacement valve that is configured to be selectively guided and implanted in a native annulus of the diseased heart valve. The replacement valve can include: a frame with a rigid portion to house and maintain the integrity of the replacement leaflets and a flexible portion enabling it to conform to the native vessel geometry, at least one prosthetic leaflet coupled to an inner surface of the stent, and a plurality of prong structures operatively coupled to and extending between portions of the at least one prosthetic leaflet and the inner surface of the bottom ventricular portion of the stent to selectively constrain the movement of the at least one prosthetic valve relative to the bottom ventricular portion of the stent.

Abstract: The present invention relates to a method for temporarily interrupting an extracorporeal treatment of blood of a patient by use of a blood treatment apparatus. The method comprises activating or controlling a control device provided and configured to bring the blood treatment apparatus into a state in which the blood treatment session of the patient can be interrupted with the intention to continue the blood treatment session. The present invention further relates to a control device, a blood treatment apparatus, a digital storage means, a computer program product as well as a computer program.

Abstract: The present invention relates to a cutter system for an electric shaver and/or trimmer, comprising a pair of comb-like cutting elements with cooperating toothed cutting edges and movably supported relative to each other by a support element, wherein lateral ends of at least one of the cutting elements are provided with lateral protection elements having rounded and/or chamfered edge contours for soft skin engagement, wherein the lateral protection element is enveloping and covering a gap movably receiving the other cutting element and/or enveloping the support element.

Abstract: A tube connector for an infusion tube is connectable to an infusion container. The tube connector has a first fluid opening that is connectable to the infusion tube or to a drip chamber connected to the infusion tube to provide a first fluid connection between the infusion container and the infusion tube. The tube connector has a second fluid opening connectable to the infusion tube to provide a second fluid connection between the infusion container and the infusion tube. The tube connector has a blocking device configured to block a fluid connection between the infusion tube connected to the second fluid opening and the infusion container connected to the tube connector to prevent a release of fluid from the infusion container into the infusion tube.