Abstract: Diabetes management systems include an insulin delivery device and a monitoring device for detecting at least one characteristic relating to the insulin delivery device. Monitoring devices may comprise pen caps.

Abstract: A user terminal configured to perform communication with an infrastructure equipment of a mobile communications network. The user terminal including a receiver configured to receive signals transmitted by the infrastructure equipment in accordance with a wireless access interface and a transmitter configured to transmit signals to the infrastructure equipment in accordance with the wireless access interface. The user terminal is configured to receive an indication on a downlink of the wireless access interface of one of a plurality of different subcarrier spacing which the communications device should use to transmit or to receive the signals representing the data.

Abstract: An arrangement for controlling flow speed in a mold for continuous casting of metal includes: at least two first front cores with associated first magnetic coils arranged on one side of the mold; at least two second front cores with associated second magnetic coils arranged on an opposite side of the mold in substantial alignment with the first front cores; an external magnetic loop connecting the second front cores to the first front cores, to allow a one-directional magnetic flux to pass through the mold from the first front cores to the second front cores or vice versa; and a control interface enabling independent control of two subsets of the first magnetic coils.

Abstract: A machining apparatus for laser machining a workpiece (12) in a machining zone (13) is provided, having a first interface (14) for a machining laser source for generating a machining laser beam (15), an outlet opening (18) for the machining laser beam (15), In an optical system between the first interface (14) and the outlet opening (18), which has at least one laser beam guiding device (22) having at least one movable surface (24) and at least one actuator (26), with which the movable surface (24) is dynamically adjustable, and a cooling device (28) for cooling the at least one actuator (26), wherein the cooling device (28) has at least one primary circuit (30) through which a first cooling fluid can flow without contact with the actuator (26). Furthermore, a set of parts for a machining apparatus for laser machining a workpiece (12) and a method of laser machining a workpiece (12) using such machining apparatus are also provided.

Abstract: An aqueous copolymer dispersion is obtained by a multi-stage emulsion polymerization process comprising polymerizing in a reaction zone in a first polymerization stage a first monomer composition comprising at least 88 wt % of a vinyl ester of a C1 to C18 carboxylic acid and up to 12 wt % ethylene to produce a first stage polymer having Tg>20° C.; and polymerizing in the reaction zone, in a second polymerization stage and in the presence of the first stage polymer, a second monomer composition comprising a vinyl ester of a C1 to C18 carboxylic acid and a C2 to C8 alkyl ester of (meth)acrylic acid to produce a second stage polymer having Tg?20° C. Each of the polymerization stages is conducted in the presence of a stabilizing system comprising at least 0.1 wt % of a protective colloid and at least 0.05 wt % of an ionic surfactant.

Abstract: Methods, computer program products and/or systems are provided that perform the following operations: obtaining a collection of objects; constructing a weighted graph based on the collection of objections, wherein the weighted graph preserves neighborhood semantics of objects of the collection of objects; generating partitions of nodes in the weighted graph of a fixed maximum size utilizing combinatorial partitioning; generating a vector for each node based on the partitions of nodes in the weighted graph; determining vector representations for objects in this collection and eventually applying this vector representation of the objects to gain efficiency (e.g., in terms of computation time and memory requirements) for use in downstream tasks such as recommendation.

Abstract: The present application discloses systems, methods, and computer-readable media that utilize computing devices to model multi-outcome transportation-value metrics that account for spatio-temporal trajectories across locations, times and other contextual features, and then utilize computer networks to dispatch provider devices to locations based on the multi-outcome transportation-value metrics. Moreover, the disclosed systems can utilize these multi-outcome transportation-value metrics and/or other models to manage and utilize dynamic transportation dispatch modes to more efficiently align provider devices and requestor devices across computer networks. For instance, the disclosed system can dispatch a provider device based on a discounted multi-outcome transportation-value metric.

Abstract: A drilling tool for producing a bore with a cylindrical inner wall can be rotatable in a rotary movement with a predetermined rotational direction (VD) about a tool axis (A) extending through the drilling tool, and at the same time is movable in an axial forward movement (VB) in a forward direction axially to the tool axis. The drilling tool comprises at least one drilling area (3) arranged in a forwardly located region of the drilling tool at a forward or free end, but preferably not having a thread forming region. The drilling area has a number n of drilling edges which are arranged offset to each other in the rotational direction, and at least one chip divider is arranged on at least one or each of the n drill cutting edges, where the chip divider forms an interruption of the respective drill cutting edge.

Abstract: A system and method for displaying image data comprise receiving 2D video data, generating, from the video data, a first plurality of intensity values of virtual primaries of a first virtual color gamut and a second plurality intensity values of a second virtual color gamut, the first plurality of intensity values being below a luminance threshold and approximating a predefined color gamut and the second plurality of intensity values being above the luminance threshold, converting the first plurality of intensity values into a third plurality of intensity values of predefined primaries of a first projection head of a display system and the second plurality of intensity values into a fourth plurality of intensity values of predefined primaries of a second projection head of the display system, and dynamically adjusting pixel levels of spatial modulators of the display system based on the third plurality and the fourth plurality of intensity values.

Abstract: Ion-selective separation by shock electrodialysis is performed by applying a voltage differential between electrodes across a porous medium to selectively draw a first species in a liquid toward at least one of the electrodes to a greater degree than a degree to which a second species in the liquid is drawn toward the same electrode. The voltage differential creates a shock in the charged-species concentration in the bulk volume of the liquid within pore channels of the porous medium, wherein the concentration of the first species in a depleted zone of the liquid bulk volume between the shock and the ion-selective boundary is substantially lower than the concentration of the second species in the liquid bulk volume between the shock and the first electrode. A dilute stream including the second species is extracted from the depleted zone separate from a concentrated stream including the first species.

Abstract: A system for action determination includes an input unit, a processing unit, and an output unit. The input unit provides the processing unit with information relating to a plurality of past actions over a period of time associated with the operation of an industrial process. The input unit provides the processing unit with information relating to a plurality of past process events over the time period associated with the operation of the industrial process. The input unit provides the processing unit with information relating to a new process event. The processing unit determines a correlation between at least some of the plurality of past actions with at least some of the past process events. The processing unit determines at least one recommended action from the information relating to the new process event, the determination including utilization of the determined correlation. The output unit outputs the at least one recommended action.

Abstract: The present invention includes surprisingly water-soluble salts of a phenylalkylamine compound that are potent antagonists of L-type calcium channels. Aqueous solutions including salts of the instant invention are formulated for nasal administration and provide a novel therapeutic platform for the treatment of stable angina, migraine, and cardiac arrhythmia, such as paroxysmal supraventricular tachycardia.

Abstract: A system and method mitigate configuration change risk for a managed service in a customer environment. Reconfiguration commands sent to a management interface are intercepted and provided to a mitigation service executing in the customer environment. The mitigation service computes a risk rating for each such command based on a wide variety of factors. If the risk is low, then the mitigation service passes the command transparently to the management interface for execution. However, if the risk is too high, then the mitigation service requests an authorization code before the command can be executed. The acceptable level of risk may be set jointly by the customer and the managed service provider according to a service level agreement. Authorization codes can confirm performance of many mitigation actions, including approval by the customer or a supervising manager, studying relevant documentation, and clean execution of the command in a testing environment.

Abstract: The present invention relates to a set of heterodimeric polypeptides and its uses in therapy, e.g. for treating cancer.

Abstract: Systems and methods for performing matrix operations using a path-number balanced optical network are provided. The optical network is formed as an array including active optical components and passive optical components arranged at a substantially central location of the array. The optical network includes at least NM active optical components which are used to implement a first matrix of any size N×M by embedding the first matrix in a second matrix of a larger size. The optical network performs matrix-vector and matrix-matrix operations by propagating one or more pluralities of optical signals corresponding to an input vector through the optical network.

Abstract: A method for displaying and processing an image includes capturing the image, calculating one or more of a size, a position, and a field of view of a first region of interest (ROI) of the captured image, calculating one or more of a size, a position, and a field of view of a second ROI of the captured image, calculating a blur factor for blurring the first ROI, manipulating an image gradient of the first ROI pixel by pixel using the blur factor to reduce at least one of a brightness or a contrast of one or more pixels of the ROI, manipulating the second ROI by changing a color of one or more pixel values from the second ROI, and displaying the processed image on a display. An imaging system which includes an image signal processor (ISP) is also described.

Abstract: This invention relates generally to anellosomes and compositions and uses thereof.

Abstract: A method for recycling a transfer product having at least one carrier film, wherein a transfer ply is arranged detachably at least partially on the at least one carrier film, and wherein the following steps are carried out in the method, in particular in the following order: a) shredding (10) the transfer product, by means of a shredder or a shredding device, into transfer product shreds, in particular carrier film shreds, preferably wherein the transfer product is present wound onto a roll, b) compressing (30) the transfer product shreds, in particular carrier film shreds, into a compact product or extruding (31) the transfer product shreds, in particular carrier film shreds, into an extrusion product.

Abstract: The present invention relates to short cyclic peptides, their use in the treatment, amelioration or prevention of a disease caused by antibodies targeting the thyrotropin-TSH receptor (TSHR) in the thyroid gland, in particular Graves' disease and orbitopathy, and to pharmaceutical compositions comprising the same.

Abstract: Disclosed are compounds of Formula I and N-oxides or salts thereof, wherein R1 is C1-C4alkyl or C3-C6cycloalkyl; R2 is H, Cl, Br or I; R3 is Cl or OR4; R4 is H or C1-C4 alkyl; R5 is H, F, Cl or CH3; and R6 is H or Cl. Also disclosed is a composition containing a compound of Formula I, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound of Formula I or a composition thereof. Also disclosed are methods for preparing a compound of Formula I.