Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.

Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof and to its use as intermediate in the preparation of 2,3-dihydrotheiazolo [3,2-a]pyrimidinium compounds, and specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo [3,2-a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.

Abstract: An optical device includes a first optically dimmable switch for providing a first transmittance while the first optically dimmable switch is in a first state and providing a second transmittance distinct from the first transmittance while the first optically dimmable switch is in a second state distinct from the first state. The optical device also includes a dynamic heat source thermally coupled with the first optically dimmable switch. The dynamic heat source is at a first temperature at a first time and is at a second temperature distinct from the first temperature at a second time mutually exclusive from the first time. The optical device may operate as an optical dimming device, which may be used in head-mounted display devices or as dimmable windows or shutters.

Abstract: A converter module is described which handles memory requests issued by a cache (e.g. an on-chip cache), where these memory requests include memory addresses defined within a virtual memory space. The converter module receives these requests, issues each request with a transaction identifier and uses that identifier to track the status of the memory request. The converter module sends requests for address translation to a memory management unit and where there the translation is not available in the memory management unit receives further memory requests from the memory management unit. The memory requests are issued to a memory via a bus and the transaction identifier for a request is freed once the response has been received from the memory. When issuing memory requests onto the bus, memory requests received from the memory management unit may be prioritized over those received from the cache.

Abstract: A novel high efficiency image projection system includes a beam-steering modulator, an amplitude modulator, and a controller. In a particular embodiment the controller generates beam-steering drive values from image data and uses the beam-steering drive values to drive the beam-steering modulator. Additionally, the controller utilizes the beam-steering drive values to generate a lightfield simulation of a lightfield projected onto the amplitude modulator by the beam-steering modulator. The controller utilizes the lightfield simulation to generate amplitude drive values for driving the amplitude modulator in order to project a high quality version of the image described by the image data.

Abstract: The present disclosure relates generally to methods of treating T-cell lymphomas with combination therapies.

Abstract: This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation Mm+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R10a, R10b, R10c, R10d, R10a?, R10b?, R10c?, R10d?, Z and Z? have the meanings as defined in the description.

Abstract: A personal care device including at least one sensor (28) configured to obtain sensor data including information about a user; a controller (30) having a feature extraction module (230) and a classifier (240), the feature extraction module configured to extract one or more features from the obtained sensor data, the classifier configured to determine a status of a user based on the extracted one or more features; and a personal care device (10) configured to provide a personal care function and receive one or more control signals to adjust the personal care function based on a determined status of at least a portion of the user's body.

Abstract: An exhaust conduit for neutralizing condensate from high efficiency gas storage water heaters is provided. The exhaust conduit includes an inlet configured to be coupled to an exhaust outlet of the heater, an outlet configured to be coupled to an exhaust vent, and a condensate chamber having an interior in fluidic communication with the inlet and the outlet. The condensate chamber has a lower portion configured to receive a neutralizer and an upper portion having a service port configured to provide access to the lower portion of the condensate chamber. The condensate chamber further includes a fluid outlet for draining the neutralized condensate via a drain line. The exhaust conduit has one or more ridges disposed in the chamber that are arranged to define a channel for directing condensate from the inlet across the neutralizer toward the fluid outlet.

Abstract: A coherency manager for receiving snoop requests addressed in a physical address space, the snoop requests relating to a cache memory addressable using a virtual address space, the cache memory having a plurality of coherent cachelines, the coherency manager comprising: a reverse translation module configured to maintain a mapping from physical addresses to virtual addresses for each coherent cacheline held in the cache memory; and a snoop processor configured to: receive a snoop request relating to a physical address; in response to the received snoop request, determine whether the physical address is mapped to a virtual address in the reverse translation module; and process the snoop request in dependence on that determination.

Abstract: In one aspect, a system is provided of verifying the accuracy of a plurality of serially-connected drug modules of a combinatorial drug delivery device, each of the drug modules including a drug reservoir, the system including: a machine-readable code located on each of the drug modules; application software configured to generate an activation code based on the machine-readable codes and the sequence of the machine-readable codes; a flow controller on the drug delivery device which is selectively actuatable to a use state to permit flow of drug from the drug delivery device; and, a control unit on the drug delivery device having a computing processing unit configured to compare the activation code with an authentication code, and, wherein, if the authentication code matches the activation code, the computing processing unit causes actuation of the flow controller to permit flow of the drug from the drug delivery device.

Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.

Abstract: An embodiment provides a device for cleaning a sleeve of an ultraviolet light source, including: the ultraviolet light source for the disinfection of a fluid, wherein the sleeve surrounds the ultraviolet light source; a cleaning composition encapsulated in a polymer material to form a compound; a canister around and in contact with the sleeve and encapsulating the compound against the sleeve thereby placing the compound in a location adjacent to the sleeve, wherein the polymer material dissolves at a pH above a target value above the polymer material dissolution point releases the cleaning composition. Other aspects are described and claimed.

Abstract: Mount and clamp assemblies employed in solar power installations are disclosed. In some embodiments, a mount assembly having a rail and opposing wings extending outwardly from the rail is disclosed. Each wing includes a top surface and a bottom surface for creating a chemical flashing, a groove and a sealant-receiving cavity extending away the bottom surface and upwardly into the wing, and a compressible seal with a circumferential pressure relief passageway. In some embodiments, a clamp having an upper member and a lower member with two horizontal flanges and a vertical flange is disclosed; in this embodiment, adjacent modules may be clamped together without an underlying structure mounted directly below to an installation surface. In another embodiment, a fourth flange is included in the mount assembly; in this embodiment, adjacent modules may be clamped together while being mounted directly to an installation surface.

Abstract: The invention relates to progenitor cells of mesodermal lineage and their use in therapy.

Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.

Abstract: A linear motor conveyor system including: at least one track section comprising: electronic circuitry housed within the track section; and a rotatable segment comprising an end profile that abuts another track section to form a stepped groove sealed by a gasket. A moving element for a linear motor conveyor system including: a body; a first set of bearings attached to the body and angled to abut against a first guide rail of a conveyor system having a protrusion with opposing angled profiles; a second set of bearing attached to the body and designed to abut against a flat profile of a second guide rail of the conveyor system.

Abstract: Surface mount assembly for mounting to a solar panel frame to an installation surface is disclosed. In some embodiments, a surface mount assembly includes a base and an enclosure. The base includes a lower member and an upper member. The lower member could include a brace, a center aperture extending through the lower and upper members for receiving a fastener to facilitate the mounting to a solar panel frame; the upper member could include a hub from which a plurality of arms may extend. The mount enclosure could include a chamber with a chamber aperture for receiving a fastener from the surface mount, a post support extending upward from the chamber and forming a post aperture for receiving a post, and a horizontal member with one or more sealant grooves extending horizontal outward from the chamber.

Abstract: Enclosure assemblies employed in electrical installations, including those employed in solar power installations, which conform to NEMA 3R type rating defined by National Electrical Manufacturers Association (“NEMA”) are disclosed. In some embodiments, a base of a housing of an enclosure assembly having a seal-receiving groove, fastener retainers, fastener walls, a moisture diverter, attachment points; and conductor pass-through apertures is disclosed. In some embodiments, a base of a housing of an enclosure assembly having a forward portion with a forward fastener retainer and forward attachment points; an aft portion of the base having an aft fastener retainer and aft and attachment points, the groove located between the forward and aft portions, a moisture diverter located between the forward and aft portions; and drainage channels encompassing the forward and aft portions is disclosed. In some embodiments, a method for pre-positioning a fastener in a housing of an enclosure assembly is disclosed.