Abstract: An instrument comprises a headpiece at a proximal end, a shaft connected to said headpiece, said shaft can be deflected at least in a distal end area thereof. A deflection mechanism is provided for deflecting said shaft. Said deflection mechanism has control wires and a control element for controlling a deflection movement of said deflection mechanism. A lock is provided for locking said deflection mechanism. Said lock has a catch mechanism connected to said control element in such a way that said catch mechanism, without actuation, is automatically forced into a locking position and a movement of said control element first opens said catch mechanism and only then permits a deflection of said shaft. A release of said control element in any position of said deflection mechanism causes an enforced locking by said catch mechanism in said position.

Abstract: An endoscopic video measurement system having a proximal operating part, an insertion part, and a replaceable head that can be inserted thereon, and where the operating part contains a connection for supplying electrical and optical power, optical transmission means for the lens illumination are provided in the insertion part for an electronic image sensor positioned in the distal end portion, and the replaceable head contains optical transmission means for the lens illumination and lens imaging, is characterized in that, in the insertion part, for transmitting a measurement beam a single-mode optical fiber is provided, with which an optical system positioned in the distal end part of the insertion part for producing a collimated sample beam bundle is associated.

Abstract: A plug-in unit with integral cable connection to the operating part of an endoscope and plug connections for lamps, mechanical, and/or electronic modules is characterized in that a hollow tube extending to the distal end of the endoscope is inserted into the plug-in unit by the integral cable connection and the operating part and has its proximal end positioned so that it is freely movable in the plug-in unit in such a way that can be conducted out of a closeable bore-hole in the wall of the plug-in unit.

Abstract: An image pick-up module and method for producing an image pick-up module. An image pick-up module, particularly for installation in an endoscope, the image pick-up module having an electronic image sensor, a first circuit board, a second circuit board and a cable.

Abstract: A method, system and computer program product provide an implementation of software. A control flow of a software component is constructed based on a specification model. In various embodiments, the specification model comprises at least one input and at least one requirement referencing the at least one input. At least a partial implementation of the software component is generated based on the control flow and the at least one input and the at least one requirement of the specification model. In some embodiments, the specification model further comprises at least one output, and the at least a partial implementation of the software component is also based on the at least one output.

Abstract: An image pick-up module and method for producing an image pick-up module. An image pick-up module, particularly for installation in an endoscope, the image pick-up module having an electronic image sensor, a first circuit board, a second circuit board and a cable.

Abstract: An instrument comprises a headpiece at a proximal end, a shaft connected to said headpiece, said shaft can be deflected at least in a distal end area thereof. A deflection mechanism is provided for deflecting said shaft. Said deflection mechanism has control wires and a control element for controlling a deflection movement of said deflection mechanism. A lock is provided for locking said deflection mechanism. Said lock has a catch mechanism connected to said control element in such a way that said catch mechanism, without actuation, is automatically forced into a locking position and a movement of said control element first opens said catch mechanism and only then permits a deflection of said shaft. A release of said control element in any position of said deflection mechanism causes an enforced locking by said catch mechanism in said position.

Abstract: Disclosed is an endoscopic system comprising an excitation beam source located in a proximal supply unit, an optical radiation transmission path in an insertion piece, and a fluorescence converter at the distal end. A laser diode that emits in the shortwave visible spectral range is used as an excitation beam source while a glass fiber is used as an optical transmission path. The fluorescence converter is suitable for converting into white light and is embodied as a fluorescent element that is mounted downstream of the light emergence surface of the glass fiber as a separate, interchangeable part. Said endoscopic system is characterized in that the distal end of the glass fiber and the fluorescent element are inserted into a lighting fixture which has a light emergence opening that widens in a funnel-shaped manner.

Abstract: A method, system and computer program product provide an implementation of software. A control flow of a software component is constructed based on a specification model. In various embodiments, the specification model comprises at least one input and at least one requirement referencing the at least one input. At least a partial implementation of the software component is generated based on the control flow and the at least one input and the at least one requirement of the specification model. In some embodiments, the specification model further comprises at least one output, and the at least a partial implementation of the software component is also based on the at least one output.

Abstract: A plug-in unit with integral cable connection to the operating part of an endoscope and plug connections for lamps, mechanical, and/or electronic modules is characterized in that a hollow tube extending to the distal end of the endoscope is inserted into the plug-in unit by the integral cable connection and the operating part and has its proximal end positioned so that it is freely movable in the plug-in unit in such a way that can be conducted out of a lockable bore-hole in the wall of the plug-in unit.

Abstract: An endoscopic video measurement system having a proximal operating part, an insertion part, and a replaceable head that can be inserted thereon, and where the operating part contains a connection for supplying electrical and optical power, optical transmission means for the lens illumination are provided in the insertion part for an electronic image sensor positioned in the distal end portion, and the replaceable head contains optical transmission means for the lens illumination and lens imaging, is characterized in that, in the insertion part, for transmitting a measurement beam a single-mode optical fiber is provided, with which an optical system positioned in the distal end part of the insertion part for producing a collimated sample beam bundle is associated.

Abstract: The present invention provides a method for preventing or treating acute or chronic graft rejection in a recipient of cell, tissue or organ allo- or xenotransplant, inflammatory or autoimmune diseases or malignant proliferative disease, comprising the use of an inhibitor of Vav. Further provided are Vav inhibitors, uses, pharmaceutical compositions and therapeutic combinations comprising Vav inhibitors, and screening methods therefore.