Patents by Inventor Martin Knauf

Martin Knauf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxyphenylundecane, a process for their production and their use
    Patent number: 7112608
    Abstract: The present invention relates to novel hydroxyphenylundecane derivatives of the formula (I), a method for the preparation of said compounds by cultivation of the fungus Cryphonectria parasitica, DSM 14453, and their use as pharmaceuticals, i.e. for the treatment of Alzheimer's Disease, Parkinson's Disease, Huntington's Diseases, stroke, psychosis and/or depressions.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: September 26, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Cordula Hopmann, Martin Knauf, Mark Brönstrup, Astrid Markus-Erb, Luigi Toti
  • Gabusectin derivatives, processes for preparing them and their use
    Patent number: 6962943
    Abstract: The present invention relates to compounds of the formula (I) which are formed by the microorganism ST 003236 (DSM 14476) during fermentation, to a process for preparing and derivatizing them, to a pharmaceutical which comprises a compound of the formula (I) and to the use thereof for producing a pharmaceutical.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: November 8, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Matthias Schiell, Martin Knauf, Luigi Toti, Astrid Markus-Erb
  • Hydroxyphenylundecane, a process for their production and their use
    Publication number: 20040122092
    Abstract: The present invention relates to novel hydroxyphenylundecane derivatives of the formula (I), 1
    Type: Application
    Filed: October 1, 2003
    Publication date: June 24, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Cordula Hopmann, Martin Knauf, Mark Bronstrup, Astrid Markus-Erb, Luigi Toti
  • Gabusectin derivatives, processes for preparing them and their use
    Publication number: 20030187057
    Abstract: The present invention relates to a compound of formula (I) 1
    Type: Application
    Filed: November 8, 2002
    Publication date: October 2, 2003
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Matthias Schiell, Martin Knauf, Luigi Toti, Astrid Markus-Erb
  • Coniosetin and derivatives thereof, process for the preparation and the use thereof
    Patent number: 6599930
    Abstract: The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I which are produced by the microorganism Coniochaeta ellipsoidea Udagawa (DSM 13856) during fermentation, wherein R, R2, R3, R4, R5, X, X2, X3 and X4 have the meanings stated in the specification, to chemical derivatives of coniosetin, to a process for their preparation and to their use as pharmaceuticals.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: July 29, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Martin Knauf, Astrid Markus-Erb, Luigi Toti, Marie-Cecile Raynal-Wetzel, Florence Fassy
  • Pluraflavins and derivatives thereof, process for their preparation and use thereof
    Patent number: 6500936
    Abstract: The invention relates to a compound of formula (I) wherein R1 is a sugar; R2 is —CH2—O—(R7)m, R7 representing a sugar, or is —COOH; R3 is an epoxide-comprising group, or is C1-C6-alkyl or C2-C6-alkenyl, unsubstituted or substituted by at least one OH; R5 is H, C1-C6-alkyl, C2-C6-alkenyl or C2-C6-alkynyl; R4R6, R8 and R10 independently of one another are H; C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, —X2H, or —X2R12, or R4 and R6 together and/or R8 and R10 together are =X2; X2 is O, NH, N—C1-C6-alkyl, N—C2-C6-alkenyl, N-C2-C6-alkynyl or S; R12 is C1-C6-alkyl, C2-C6—alkenyl, C2-C6-alkynyl, aryl or acyl; and m and n are 1 or 2; in any of its stereochemical forms and mixtures of these forms in any ratio, and a physiologically acceptable salt or derivative thereof. The compounds are obtainable from a culture of the microorganism Actinomycetales species HAG 003959, DSM 12931, by fermentation.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: December 31, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Martin Knauf, Joachim Wink, Francis P. Barbone, Elaine A. Powers, Elizabeth A. Cashman
  • Coniosetin and derivatives thereof, process for the preparation and the use thereof
    Publication number: 20020137788
    Abstract: The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I 1
    Type: Application
    Filed: December 6, 2001
    Publication date: September 26, 2002
    Inventors: Laszlo Vertesy, Martin Knauf, Astrid Markus-Erb, Luigi Toti, Marie Cecile Raynal-Wetzel, Florence Fassy
  • Pluraflavins and derivatives thereof, process for their preparation and use thereof
    Publication number: 20020028921
    Abstract: The invention relates to a compound of formula (l) 1
    Type: Application
    Filed: February 16, 2001
    Publication date: March 7, 2002
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Martin Knauf, Joachim Wink, Francis P. Barbone, Elaine A. Powers, Elizabeth A. Cashman
  • Methods of treatment with novel antibiotic feglymycin
    Patent number: 5994307
    Abstract: This invention relates to the antibiotic feglymycin, as well as processes for its preparation and use. Feglymycin is represented by the structural formula (SEQ. ID. NO.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: November 30, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Martin Knauf, Joachim Wink, Dieter Isert, Wilhelm Stahl, Gunther Riess, Jozsef Aszodi, Dominique Le Beller
  • Antibiotic, feglymycin, processes for its preparation and its use
    Patent number: 5891851
    Abstract: This invention relates to the antibiotic feglymycin, as well as processes for its preparation and use.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: April 6, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Martin Knauf, Joachim Wink, Dieter Isert, Wilhelm Stahl, Gunther Riess, Jozsef Aszodi, Dominique Le Beller