Abstract: The present disclosure relates to a method of treating an acute inflammatory disorder such as septic shock in a subject in need thereof. The method involves administering to a subject who has a soluble TREM-1 (sTREM-1) level measured in a biological sample from the subject greater than a predetermined sTREM-1 value an amount of a TREM-1 inhibitor sufficient to treat the inflammatory disorder.

Abstract: An apparatus for structuring a roller surface is proposed, wherein the apparatus has a laser source and an optical system, wherein the laser source is designed for generating laser pulses, wherein the optical system has at least one beam shaper, at least one beam splitter, and a focusing unit, wherein the combination of beam shaper and beam splitter is arranged between the laser source and the focusing unit.

Abstract: The present invention relates to a connecting device (10) for connecting a first line end (12) to a second line end (14), wherein the first line end (12) has a flange-like radial first widening (16) with a first end face (18) and a first rear face (20), and the second line end (14) has a plurality of flange-like radial second widenings (22) each with a second end face (24) and a second rear face (26), wherein the second widenings (22) are separated from one another by interruption portions (84), and the connecting device (10) comprises a connecting ring (74) with a first closure face (76) and a plurality of second closure faces (70) which are separated from one another by passage portions (80), wherein the first closure face (76) can be brought into contact with the first rear face (20), and the second closure faces (78) can be brought into contact with the second rear faces (26) by virtue of the fact that the second widenings (22) are guided with an axial movement through the passage portions (80) and then a

Abstract: In some implementations, a system may include a server equipped with a web application, where the web application is configured to detect a relocation of a network-enabled electric plug of network-enabled electric plugs from a first region to a second region based on changes in data communication patterns; the network-enabled electric plugs, each plug configured to deliver electricity from an electrical source to a powered device and capable of communicating with the server; and an access point intermediary facilitating communication between the network-enabled electric plugs and the server.

Abstract: A region-based electrical intelligence system is used to configure and control electrical usage within regions, for example, within certain areas of a floor of a building or within certain floors of a building. A number of network-enabled electric plugs are deployed in a region. Each of the network-enabled electric plugs is configured to deliver electricity from an electricity source to one or more powered devices located in the region. A server runs a web application used to monitor electrical usage information for the region based on electrical usage by each of the one or more powered devices. The web application generates rules for selectively controlling the delivery of electricity from the network-enabled electric plugs to the powered devices based on the monitored electrical usage information.

Abstract: A method for producing a sheet metal product (1) from a sheet metal preliminary product (2) is proposed, wherein at least one surface (7) of the sheet metal preliminary product (2) is coated with a coating, wherein the sheet metal preliminary product (2) is rolled, wherein depressions (6) are rolled into the surface (7) during the rolling operation, wherein after the coating and rolling operations lubricant (8.1) is introduced into the depressions (6), wherein after the introduction of lubricant (8.1) the sheet metal preliminary product (2) is mechanically formed by a forming tool (5), characterized in that the surface (7) is coated in such a way that, in the forming tool (5) during the forming process, in particular under relative movement between sheet metal surface and tool surface, the coating is elastically deformable under loads of 0.5 MPa to 20 MPa and plastically deformable under loads of above 20 MPa.

Abstract: The invention relates to sheet metal packaging products, in particular tinplate or electrolytically chrome-plated sheet steel (ECCS), consisting of a sheet steel substrate (S) with a thickness in the region of 0.1 mm to 0.6 mm and a coating (B), in particular made of tin and/or chromium or chromium and chromium oxide, that is electrolytically deposited on at least one side of the sheet metal substrate. In addition, at least one surface of the sheet metal packaging product provided with the coating (B) has a surface profile with periodically repeating structure elements in at least one direction, wherein an autocorrelation function resulting from the surface profile has a plurality of side lobes with a height of at least 20%, preferably at least 30% of the height of the main lobe. These sheet metal packaging products have improved and novel surface properties.

Abstract: A method and a device connects a partially flexible protective cover (2) sealed against the environment and forming a barrier between a contaminated area (12) and an uncontaminated area, to a partially flexible safety cover (20) by transferring the protective cover (2) out of the contaminated area (12) inverting the protective cover (2) over an opening such that its inside is turned out and then severing it from the safety cover (20) and closing the opening; or transferring the protective cover (2) from the contaminated area (12) by sheathing the protective cover (2) with the safety cover (20) as it is pulled through a passage and subsequently severing of both covers (2, 20) from the safety cover (20) and closing the sheathing; or pulling the protective cover (2) back into the contaminated area (12) and then sealing the ends shut to sever the safety cover (20) by forming a further sealed joint between adjacent film parts.

Abstract: A region-based electrical intelligence system is used to configure and control electrical usage within regions, for example, within certain areas of a floor of a building or within certain floors of a building. A number of network-enabled electric plugs are deployed in a region. Each of the network-enabled electric plugs is configured to deliver electricity from an electricity source to one or more powered devices located in the region. A server runs a web application used to monitor electrical usage information for the region based on electrical usage by each of the one or more powered devices. The web application generates rules for selectively controlling the delivery of electricity from the network-enabled electric plugs to the powered devices based on the monitored electrical usage information.

Abstract: A coupling system provides a media-conducting connection of two hose-shaped sections (10, 12). Each section has one coupling element (16, 18), with two coupling parts (20, 22) that can be separated from each other and that are detachably held to each other by closure elements (24) along a disconnecting point (26). The closure parts of one coupling element can be engaged with correspondingly designed closure elements (24) of the other coupling element (20, 22) to form the transport section. All closure elements (24) of the coupling parts (20, 22) point hose-inward, at least before forming the transport section. Upon producing the transport section, the respective disconnecting point (26) is arranged between the coupling elements (16, 18), transversely to the transport section.

Abstract: An apparatus for structuring a roller surface is proposed, wherein the apparatus has a laser source and an optical system, wherein the laser source is designed for generating laser pulses, wherein the optical system has at least one beam shaper, at least one beam splitter, and a focusing unit, wherein the combination of beam shaper and beam splitter is arranged between the laser source and the focusing unit.

Abstract: A method for identifying human subjects suffering from an inflammatory disorder susceptible to respond to a therapy, in particular to a TREM-1 inhibitor. In particular, an in vitro method for identifying a human subject suffering from an inflammatory disorder, preferably an acute inflammatory disorder such as SIRS, sepsis or septic shock, susceptible to respond to a therapy, in particular to a TREM-1 inhibitor. The method includes the steps of a) measuring the level of soluble triggering receptors expressed on myeloid cells-1 (sTREM-1) in a biological sample from the human subject, comparing the level of sTREM-1 measured at step a) to a predetermined sTREM-1 value, and c) identifying a human subject suffering from an inflammatory disorder with a level of sTREM-1 measured at step a) higher than the predetermined sTREM-1 value of step b) as susceptible to respond to a therapy, in particular to a TREM-1 inhibitor.

Abstract: A region-based electrical intelligence system is used to configure and control electrical usage within regions, for example, within certain areas of a floor of a building or within certain floors of a building. A number of network-enabled electric plugs are deployed in a region. Each of the network-enabled electric plugs is configured to deliver electricity from an electricity source to one or more powered devices located in the region. A server runs a web application used to monitor electrical usage information for the region based on electrical usage by each of the one or more powered devices. The web application generates rules for selectively controlling the delivery of electricity from the network-enabled electric plugs to the powered devices based on the monitored electrical usage information.

Abstract: The connecting rod head includes at least one oil chamber and an eccentric comprises a protrusion reaching into the oil chamber, so that an oil pressure in the oil chamber exerts a force on the protrusion to change the eccentric setting of the eccentric.

Abstract: The present disclosure describes systems, apparatus, and methods for application of dynamic magnetic field (DMF) treatment to direct movement, and specifically rotation, of magnetic particles associated with a target structure, so that mechanical force is applied to the target structure. In certain embodiments, the present disclosure demonstrates application of DMF treatment to direct rotation about the axis in individual magnetic particles (e.g., superparamagnetic nanoparticles), effecting permeabilization and/or other disruption of membranes (e.g., cell membranes and/or intracellular membranes). In certain embodiments, the present disclosure describes use of an alternating current superconductor (ACSC) to greatly enhance the magnetic field amplitude so that the field can penetrate deeper into a body with sufficient amplitude to control movement of the nanoparticles within a working volume.

Abstract: 1. Method and device for connecting a protective cover to a safety cover sealed against the environment. 2.

Abstract: A region-based electrical intelligence system is used to configure and control electrical usage within regions, for example, within certain areas of a floor of a building or within certain floors of a building. A number of network-enabled electric plugs are deployed in a region. Each of the network-enabled electric plugs is configured to deliver electricity from an electricity source to one or more powered devices located in the region. A server runs a web application used to monitor electrical usage information for the region based on electrical usage by each of the one or more powered devices. The web application generates rules for selectively controlling the delivery of electricity from the network-enabled electric plugs to the powered devices based on the monitored electrical usage information.

Abstract: The connecting rod head includes at least one oil chamber and an eccentric comprises a protrusion reaching into the oil chamber, so that an oil pressure in the oil chamber exerts a force on the protrusion to change the eccentric setting of the eccentric.

Abstract: A flat product made of a metal material has been provided with deterministic surface texture which has a plurality of depressions which have a depth in the range of from 2 to 14 ?m, wherein the depressions are designed to be I-shaped, H-shaped, cross-shaped, C-shaped or X-shaped, and wherein the surface texture has a peak count RPc in the range of from 45 to 180 1/cm, an arithmetic mean roughness Ra in the range of from 0.3 to 3.6 ?m, and an arithmetic mean waviness Wsa in the range of from 0.05 to 0.65 ?m.

Abstract: The invention relates to a transport system for pourable and flowable media having a coupling device (56), consisting of at least one first connection part (14) and a plurality of further connection parts (54), which are connected to the first connection part (14) by means of flexible, tubular connecting parts (16), which can be blocked by means of at least one closing device (68), after the release of which the connecting part (16) that can be associated is open for media transport, wherein, after media transport has occurred along a specified transport path, said transport path is blocked by means of a separate blocking device or is closed again by the closing device (68).