Abstract: This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.

Abstract: The invention relates to substituted sulphoximines according to the general formula (I): in which A, E, G, X, R1, R2, R3, R4, R5, R6, R7, R8, m, p, q, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted sulphoximines, to methods of preparing said substituted sulphoximines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 signalling.

Abstract: The proposed iterative method concurrently calculates maximum likelihood estimated values for the channel coefficients (h0, . . . , hL; ?h) and the DC offset (d; ?d) on the basis of a training sequence (TSC) in a TDMA mobile communications system. The SAGE algorithm leads to two recursion formulae, by means of which the iterative calculation of estimated values for the channel coefficients (h0, . . . , hL; ?h) and for the DC offset (d; ?d) is provided.

Abstract: This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.

Abstract: A method for equalization of a signal is provided, wherein the equalization is of a signal that is transmitted via a data channel based on the DF method. The method takes account of at least one interference channel, and includes processing of at least two trellis diagrams in each time unit, with the states of at least one of the trellis diagrams describing the data channel. A DF contribution that is used for processing of this trellis diagram includes information about at least one interference channel.

Abstract: In a method for correlative estimation of a mobile radio channel on the basis of a training sequence (TS) which is transmitted via the mobile radio channel, a sequence of P received symbols is correlated with a subsequence of length P of the training sequence, in order to calculate a first estimated channel coefficient (?0(1)). Furthermore, the same sequence of P received symbols is correlated with at least some of the subsequences of the training sequence (TS) shifted through ±1, ±2, . . . , ±(Lt?1) symbol positions, in order to calculate a number of further estimated channel coefficients (?±1(1),?±2(1), . . . ,?±(Lt?1)(1)).

Abstract: In a method to compensate for a step DC disturbance (1) in a baseband signal in a homodyne radio receiver, the time profile of the step DC disturbance within a burst is determined. In order to produce a step-corrected baseband signal, the determined time profile (2) is then calculated from the digitized baseband signal.

Abstract: A system having a signal processor for detection of a signal type of a signal has a processor is disclosed. One embodiment is designed to determine a first variable which is characteristic of a first spectrum element of the signal spectrum, and to determine a second variable which is characteristic of a second spectrum element of the signal spectrum, a system for determination of a ratio between the first variable and the second variable, and a detector which is designed to detect the signal type on the basis of the ratio.

Abstract: A system and apparatus for establishing whether a received signal frame is an audio signal frame is disclosed. In one embodiment, the system includes a predetermined position in an audio signal frame containing a piece of secondary information for an audio characteristic of the audio data, with a selection device for selecting a succession of bits which is arranged at the predetermined position in the received signal frame. A decision-making device flags the received signal frame as an audio signal frame if the succession of bits represents the piece of secondary information.

Abstract: Novel VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones and their use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are selected.

Abstract: Novel VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridones and their use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are selected.

Abstract: The invention relates to novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis.

Abstract: The invention relates to anthranilic acid amides and the use thereof as medicaments for the treatment of diseases that are triggered by persistent angiogenesis, in addition to intermediate products in the production of anthranilic acid amides.

Abstract: Ortho-substituted anthranilic acid amides and use thereof as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described.

Abstract: The invention relates to novel nicotinamide pyridinureas as VEGF receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis.

Abstract: Only a single, standard-independent clock rate is generated in a signal processor or a signal processing structure, and correspondingly only precisely one clock frequency generator is then arranged on the chip. The signal processing path includes at least one controllable, asynchronous decimator for transposing the reception signals present in a uniform time frame into a respective standard-specific time frame. This enables signals of a variety of mobile phone standards to be processed.

Abstract: The invention relates to novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors, their production and use as pharmaceutical agents for preventing or treating diseases that are triggered by persistent angiogenesis.

Abstract: In a method for error correcting a data signal that is transmitted via a channel and contains data blocks with associated error checking information, the data signal is first equalized, with calculated soft-bit information. In a subsequent step, the error checking information is evaluated with respect to the data block. If the evaluation of the error checking information shows that a single bit error is present in one message bit, the single bit error is corrected only when a condition that is dependent on the soft-bit information is satisfied.

Abstract: Substituted anthranilamides and use thereof as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis as well as their intermediate products for the production of anthranilamides are described.

Abstract: Described are compunds of formula (I), wherein W is O or S; X is NR8; Y is CR9R10—(CH2)n wherein R9 and R10 are independently of each other hydrogen or lower alkyl, and n is an integer of from and including 0 to and including 3; or Y is SO2; R2 is aryl; R2 is a mono- or bicyclic heteroaryl group comprising one or more ring nitrogen atoms with the exception that R2 cannot represent 2-phthalimidyl, and in case of Y=SO2 cannot represent 2,1,3-benzothiadiazol-4-yl; any of R3, R4, R5 and R6, independently of the other, is H or a substituent other than hydrogen; and R7 and R8, independently of each other, are H or lower alkyl; or a N-oxide or a pharmaceutically acceptable salt thereof for the preparation of a pharmaceutical product for the treatment of a neoplastic disease which responds to an inhibition of the VEGF receptor tyrosine kinase activity. The compounds of formula (I) can be used for the treatment e.g. of a neoplastic disease, such as a tumor disease, of retinopathy and age-related macular degeneration.