Abstract: A kit for optically detecting proteins, in particular lipoproteins, in a sample, the kit comprising: a chip for performing a separation of the proteins, in particular of the lipoproteins, wherein the chip comprises at least one well for receiving the sample, and a separation channel coupled to the at least one well and being adapted for separating different compounds and a marker dye which contains a polymethine of the general formula (I) wherein Z is a substituted derivative of benzooxazole, benzodiazole, 2,3,3-trimethylindolinine, 2,3,3-trimethyl-4,5-benzo-3H-indolinine, 3- and 4-picoline, lipidine, chinadine and 9-methylacridine derivatives with the general formula IIa or IIb or IIc and wherein X is selected from the group consisting of O, S, Si, N-alkyl and C(alkyl)2, n is 0, 1 , 2 or 3, R1 to R14 are independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, linear or branched alkenyl, cycloalkenyl, aryl, heteroaryl, heterocycle, hydroxy, carboxy, amine, alkyl-substituted am

Abstract: An electrophoresis gel matrix is provided for conducting proteomics, in particular the steps of separating and/or identifying proteins. The matrix comprises at least one chemical reagent being at least one of a denaturing, buffering, disaggregating, reducing, staining or dissolving reagent, and a volume of dimethylsulfoxide. The use of such a matrix, which is provided to be filled into an electrophoresis capillary being part of a microfluidic device for carrying out proteomics, leads to an enhanced resolution of proteins. The matrix is prepared adding a volume of dimethylsulfoxide ranging from 4% to 15%, preferably from 5% to 10%, most preferably from 6% to 8% with respect to the total volume of chemical reagents being comprised in the matrix. A method is provided for preparation of the matrix for conducting proteomics and a method is conducted to carry out proteomics by the use of this matrix.

Abstract: A kit for optically detecting proteins, in particular lipoproteins, in a sample, the kit comprising: a chip for performing a separation of the proteins, in particular of the lipoproteins, wherein the chip comprises at least one well for receiving the sample, and a separation channel coupled to the at least one well and being adapted for separating different compounds and a marker dye which contains a polymethine of the general formula (I) wherein Z is a substituted derivative of benzooxazole, benzodiazole, 2,3,3-trimethylindolinine, 2,3,3-trimethyl-4,5-benzo-3H-indolinine, 3- and 4-picoline, lipidine, chinadine and 9-methylacridine derivatives with the general formula IIa or IIb or IIc and wherein X is selected from the group consisting of O, S, Si, N-alkyl and C(alkyl)2, n is 0, 1 , 2 or 3, R1 to R14 are independently selected from the group consisting of hydrogen, alkyl, alkoxy, cycloalkyl, linear or branched alkenyl, cycloalkenyl, aryl, heteroaryl, heterocycle, hydroxy, carboxy, amine, alkyl-substituted am

Abstract: A sample loading device for loading and injecting a sample of a specimen is provided. The device comprises an injection channel having a sample injection spot, the injection channel adapted for feeding a fluid comprising a specimen. It further comprises an injector for injecting the specimen into the fluid along the injection channel and a separation device adapted for separating a sample from the specimen at the sample injection spot. Furthermore it comprises a control unit adapted for controlling the separation device in response to a detected physical parameter of the fluid.

Abstract: An electrophoresis gel matrix is provided for conducting proteomics, in particular the steps of separating and/or identifying proteins. The matrix comprises at least one chemical reagent being at least one of a denaturing, buffering, disaggregating, reducing, staining or dissolving reagent, and a volume of dimethylsulfoxide. The use of such a matrix, which is provided to be filled into an electrophoresis capillary being part of a microfluidic device for carrying out proteomics, leads to an enhanced resolution of proteins. The matrix is prepared adding a volume of dimethylsulfoxide ranging from 4% to 15%, preferably from 5% to 10%, most preferably from 6% to 8% with respect to the total volume of chemical reagents being comprised in the matrix. A method is provided for preparation of the matrix for conducting proteomics and a method is conducted to carry out proteomics by the use of this matrix.

Abstract: A medium for use in electrophoresis comprising N-methylurea and a polyacrylamide gel. In particular, the medium is used in a system and method of electrophoretic separation comprising the introduction of a sample to the medium, and applying an electric field across the medium.

Abstract: A medium for use in electrophoresis comprising N-methylurea and a polyacrylamide gel. In particular, the medium is used in a system and method of electrophoretic separation comprising the introduction of a sample to the medium, and applying an electric field across the medium.