Abstract: A neural network (such as a transformer neural network) configured to determine radiation doses can be trained using a training corpus that comprises a plurality of different resultant radiation doses (such as, but not limited to, sparsely-written resultant radiation doses) and a plurality of different input items that each correspond to a particular one of the plurality of different resultant radiation doses. Those input items can comprise at least one, two, three, or each of a patient image (such as, but not limited to, computed tomography imagery and/or Digital Imaging and Communications in Medicine-compatible imagery), a fluence map, radiation treatment platform geometry information, and/or target dose volume information (such as, but not limited to, sparsely-read target dose volume information). A radiation dose for a patient can be generated by providing patient image information as input to a trained neural network and outputting a determined radiation dose for the patient.

Abstract: A computer-implemented method includes receiving first medical image data, wherein the first medical image data is based on a first medical imaging of an examination object, receiving second medical image data, wherein the second medical image data is based on a second medical imaging of the examination object, wherein the first and the second medical imaging differ by at least one of an imaging modality or by an imaging protocol used, wherein the first and the second medical image data are registered with one another, determining synthetic image data by applying a trainable function to the first medical image data, determining a measure of similarity with a similarity function by comparison of the synthetic image data and the second medical image data, adjusting at least one parameter of the trainable function by optimization of the similarity function based on the measure of similarity, provision of the trainable function.

Abstract: The disclosure relates to a method (100) of optically analyzing a blood cell from a blood sample with a device for optically analyzing a blood cell from a blood sample, the device (1) comprising a microfluidic chamber with at least one fluidic flow-through channel, a first inlet (6) port configured to introduce at least a part of the blood sample into the fluidic channel, a first outlet (7) port configured to discharge at least a part of the blood sample from the fluidic channel, a flow generating and stopping device configured to generate a flow of the sample through the channel and to stop the flow while a least a part of the sample comprising at least one blood cell is situated within the channel and wherein after stopping the flow the sample is only influenced by gravity and inertial forces such that blood cells within the sample sediment on a first area of a lower surface of the channel, wherein cells sedimented within the first area of the lower surface can be optically analyzed in the chamber.

Abstract: The invention relates to a device for observing a biological probe. The device comprises an optical microscope, a beam splitting device and a plurality of cameras. The optical microscope comprises a support structure for supporting the biological probe in a beam path of the optical microscope. The beam splitting device is arranged in the beam path downstream from the biological probe, wherein the beam splitting device is configured to split the beam path into a plurality of beam paths. Each camera is arranged in one beam path of the plurality of beam paths and is configured to generate camera images of the biological probe. For at least some of the cameras, focal lengths of the cameras differ from one another and/or wavelength ranges captured by the cameras for generating the camera images of the biological probe differ from one another and/or sensor types of the cameras differ from one another.

Abstract: A functional component and having a partial plastic housing element with a plastic housing wall, the plastic housing wall having a device identification region integrated into the plastic housing wall and thus realizing a constituent part of the plastic housing wall. The device identification region comprising identification elements integrated into the plastic housing wall, those identification elements that realize part of a surface of the plastic housing wall realizing device identification elements, the device identification region being realized individually for the device by the device identification elements, such that the device can be unambiguously identified by means of the device identification region.

Abstract: A meta-learning system includes an inner function computation module, adapted to compute output data from applied input data according to an inner model function, depending on model parameters; an error computation module, adapted to compute errors indicating mismatches between the computed output data and target values; a state update module, adapted to update the model parameters of the inner model function according to an updated state, updated based on a current state of the state update module, in response to an error received from the error computation module. The state update module is learned to adjust the model parameters of the inner model function, such that a following training of the inner model function with training data is improved.

Abstract: A method and a system are for performing at least one inference task on medical input data. In an embodiment, the system includes: a computing device configured to implement an artificial neural network, ANN. The ANN is configured to receive medical input data as an input and to perform at least one inference task based on the medical input data. The ANN includes an output layer with, for at least one inference task of the at least one inference task, a plurality of output nodes. Each output node corresponds to one quantile out of a plurality of defined quantiles.

Abstract: Various example embodiments pertain to processing images that depict tissue samples using a neural network algorithm. The neural network algorithm includes multiple encoder branches that are copies of each other that share the same parameters. The encoder branches can, accordingly, be referred to as Siamese copies of each other.

Abstract: A power semiconductor module has a first and second intermediate circuit rail, an AC potential rail and with a packaged first and second power semiconductor switch. The respective power semiconductor switch has a first and second load current terminal and a control terminal, wherein the first power semiconductor switch is between the first intermediate circuit rail and the AC potential rail and the second power semiconductor switch is between the second intermediate circuit rail and the AC potential rail. The first load terminal of the first power semiconductor switch is contacted to the first intermediate circuit rail and the second load terminal of the first power semiconductor switch is electrically conductively contacted to the AC potential rail.

Abstract: A system and a method are provided for a parameter update. In an embodiment, the method includes obtaining, by a first entity, a function and parameter data from a second entity; selecting data samples provided by the first entities; providing a plurality of mutually isolated computing instances; assigning and providing the selected data samples to the computing instances; calculating, within each computing instance, results of the function; calculating averages over the results; determining whether the function fulfils a security criterion, and, if so: providing the calculated average for the gradient of the loss function and/or the calculated average of the output value and/or updated parameter data to the second entity.

Abstract: A hand-held power tool, in particular a combi drill, which includes a drive unit for transferring a working movement to an insertion tool, a machine housing that is designed in particular as a handle housing made of plastic, and an interface unit that is detachably fastenable to a rechargeable battery unit. The interface unit includes a retaining unit that is provided for holding the rechargeable battery unit in a fastened state connected to the hand-held power tool. It is provided that the retaining unit includes metal.

Abstract: A switchable gear drive for a handheld power tool has two gears which are to be engaged via an adjustable switching member, the switching member being in a locked position with a retaining ring which is fixedly held on a housing in a first gear and being in an unlocked position with the retaining ring in a second gear. Furthermore, a spindle for accommodating a tool is drivable by an axially spring-loaded gear wheel supported in the housing, the gear wheel being axially supported on the retaining ring on the side diametrically opposed to the switching member. The retaining ring is designed as a circumferential, closed ring.

Abstract: A hand-held machine tool device, in particular, for a screwdriver (12a-h), having a locking device (14a-h) for locking a power take-off unit (16a-h), and having a rotational bearing device (18a-h) of the power take-off unit (16a-h). It is provided that at least part of the locking device (14a-h) and the rotational bearing device (18a-h) be formed in one piece.

Abstract: In a hand-held machine tool, having a tool holder for holding at least one first tool, which has a tang having a first coupling contour that is able to be connected to the tool holder and having a striking mechanism for the striking drive of the first tool connected to the tool holder in the axial direction of the tool holder in a striking operation associated with the hand-held machine tool, a chuck adapter is provided to hold at least one second tool, which has a tang provided with a second coupling contour, which is able to be connected to the chuck adapter in a torsionally fixed manner.

Abstract: A power drill having percussion drilling function, drilling function and screwing function has a gearing for transmitting the drive motion of a drive unit to a tool spindle. Furthermore, two latching elements are provided which, in the percussion drilling function, are in latching engagement and in the drilling or screwing position are in the disengaged state. A mode setting device has a rotatable supporting ring and a thrust ring, coupled to the supporting ring in a torsionally fixed manner which, in the screwing position is held on the gear housing in an axially displaceable manner.

Abstract: A hand-held power tool having hammer-drilling, drilling and screwing modes, including a mode-setting device having an actuating element, a setting element, and a gear unit for driving an output shaft, in which the actuating and setting elements are interconnected in a rotatably fixed manner, and, in an operating mode(s), the setting element is coupled to a transmission element supported at a coupling housing assigned to the gear unit and axially displaceable at the coupling housing in a screwing position associated with the screwing mode and is axially fixed in position at the coupling housing in hammer-drilling and drilling positions of the corresponding modes; the transmission element is connected to the coupling housing in a rotatably fixed manner, a predefined operating mode being settable by rotating the setting element; the setting and transmission elements being rotatable relative to one another, the setting element embracing at least sections of the transmission element.

Abstract: A hand-held power tool is provided which includes a clutch housing of a torque clutch, and a planetary gear, situated in a gear housing, for transmitting a torque which is generated by a drive motor to a drive shaft. The clutch housing cooperates with the planetary gear via a pressure plate. The pressure plate is displaced in the axial direction in order to disengage the torque clutch. The axial relative motion of the pressure plate causes an axial relative motion between a switching element and an associated optical sensor, via which the drive motor may be switched off.

Abstract: A power tool, in particular a hand-held power tool, preferably embodied as a cordless screwdriver, is equipped with a torque limiting unit in which the release torque is settable by way of a locking brace that is equipped with a spring brace for locking elements that abut axially against parts of a planetary drive, in particular the ring gear thereof or the planet carrier thereof as a last gear stage, the spring elements of the spring brace and the locking elements being located with a radial offset from one another.

Abstract: The hydroisomerization of a paraffinic hydrocarbon feedstock obtained from renewable sources is effectively achieved by passing the feedstock in the presence of hydrogen over a hydroisomerization catalyst comprising a crystalline metal silicate molecular sieve, in which a portion of the crystalline framework contains iron.

Abstract: In a handheld electric tool having a tool housing in which is disposed a gearbox for transferring a torque, generated by a drive motor, to a drive spindle with which a spindle locking apparatus is associated, the drive spindle being rotatably mounted in the tool housing at at least two bearing points, the at least two bearing points are provided in the tool housing in a region downstream from the gearbox, and the spindle locking apparatus is disposed between the two bearing points in an axial direction of the drive spindle.