Patents by Inventor Martin Kupiec

Martin Kupiec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for searching for homing endonucleases, their genes and their targets
    Patent number: 8566040
    Abstract: A computer implemented method for generating nucleotide sequences containing candidate homing endonuclease genes (HEGs). A search is performed in a database stored on a storage medium of nucleotide sequences for amino acid sequences having a subsequence having a homology level with the translation of a subsequence of one or more predetermined HEGs. For each amino acid sequence generated by the search, one or more nucleotide sequences are retrieved encoding the amino acid sequence. The results of this search used in a second search of a database stored on a storage medium to generate the HEG containing sequences.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: October 22, 2013
    Assignee: Ramot at Tel-Aviv University Ltd
    Inventors: Adi Barzel, Eyal Privman, David Burstein, Uri Gophna, Martin Kupiec, Tal Pupko
  • Homing endonuclease genes and their targets
    Publication number: 20110064717
    Abstract: The invention provides pharmaceutical composition having as an active ingredient either a homing endonuclease (HE) capable of cleaving a non-native target nucleotide sequence in a genome or a nucleotide sequence encoding for a HE capable of cleaving a target site in a non-native genome. The invention also provides uses for such HEs, and methods of treatment utilizing such HEs. The HE may be, for example, any one of the HEs PI-SceI, POLB HE, PRP8 HE, or Nostoc species PCC7120 HE.
    Type: Application
    Filed: August 20, 2010
    Publication date: March 17, 2011
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Adi Barzel, Eyal Privman, Michael Pe'eri, Martin Kupiec, Tal Pupko
  • METHOD FOR SEARCHING FOR HOMING ENDONUCLEASES, THEIR GENES AND THEIR TARGETS
    Publication number: 20100317724
    Abstract: A computer implemented method for generating nucleotide sequences containing candidate homing endonuclease genes (HEGs). A search is performed in a database stored on a storage medium of nucleotide sequences for amino acid sequences having a subsequence having a homology level with the translation of a subsequence of one or more predetermined HEGs. For each amino acid sequence generated by the search, one or more nucleotide sequences are retrieved encoding the amino acid sequence. The results of this search used in a second search of a database stored on a storage medium to generate the HEG containing sequences.
    Type: Application
    Filed: February 12, 2009
    Publication date: December 16, 2010
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Adi Barzel, Eyal Privman, David Burstein, Uri Gophna, Martin Kupiec, Tal Pupko