Abstract: The present invention relates to a phase-locked loop for frequency synthesis, which has a memory for a control value for the controllable oscillator of the phase-locked loop, which is connectable via a first switch to the control input of the controllable oscillator and is implemented to output a stored control value, and whose frequency divider is connectable at its output via a second switch to the reference oscillator.

Abstract: Compounds of formula (I) and salts and physiologically functional derivatives thereof, wherein R2 is attached at the 4- or 5-position of the thiazole ring and is hydrogen, alkyl, halogen, cyano, alkoxy, haloalkoxy, or alkylamino; X independently represents a divalent linkage group selected from S, O, NR4, SO, or SO2; R4 is hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, or heterocyclyl; R1 is attached at the 4- or 5-position of the thiazole ring and independently represents a group of formula (II): ?wherein the dotted line represents a single or double bond; * indicates the point of attachment to the thiazole ring; and n is 1, 2, or 3. Also disclosed are pharmaceutical compositions comprising the above compounds and method of treatments for cancer and other diseases.

Abstract: A system and appertaining method provide for pre-fetching records from a central data base to a local storage area in order to reduce delays associated with the data transfers. User patterns for requesting data records are analyzed and rules/strategies are generated that permit an optimal pre-fetching of the records based on the user patterns. The rules/strategies are implemented by a routine that pre-fetches the data records so that users have the records available to them when needed.

Abstract: The present invention relates to the use of compounds of the general Formula (XIII): wherein A7 is C?O, C?S, SO2, CH—OR13, C?NR12, or CH2—CHOR13; A8 is C(R14)2, O, S, or NR12; A9 is C?O, C?S, SO2, CH—OR13, C?NR12, or CH2—CHOR13; m is 0, or 1 q is 0, or 1 r is 0, or 1 R12 is H, CH3, CH2—CH3, C6H5, OCH3, OCH2—CH3, OH, or SH; R13 is H, CH3, or CH2—CH3; R14 is H, alkyl, alkoxy, OH, or SH;

Abstract: The present invention relates to compounds of the general formula (I) and salts, prodrugs, and stereoisomers thereof, wherein Y independently represents S, O, NR2, SO, SO2; A independently represents a fife- or six-membered aromatic carbocycle or heterocycle and wherein R1 to R20 in formula (I) represent independently of each other a variety of different substituents comprising alkyl, aryl, aralkyl, alkylaryl, heteroaryl groups and monofunctional moieties.

Abstract: The invention relates to a process for regenerating the adsorbers of adsorber stations in the crude gas stream of installations for obtaining gas products from synthesis gas with the aid of a cryogenic gas separation unit. A part-stream from the purified synthesis gas stream, which is taken off downstream of the adsorber station but upstream of its cryogenic separation and is fed to the adsorber to be regenerated, is used as regeneration gas. The laden regeneration gas is either fed back to the crude synthesis gas stream upstream of the CO2 scrub, admixed to a product stream or removed from the installation.

Abstract: The present invention relates to compounds of the general formulas (I), (Ia) and (II) and salts and physiologically functional derivatives thereof, wherein the substituents —Y are attached to the 5- or 6-position of the benzazole.

Abstract: The present invention relates to N2-heteroaryl-benzazole-2,(5 or 6)-diamine derivatives and compositions thereof as protein kinase inhibitors for the treatment of e.g. cancer.

Abstract: A method of making a wireless communication connection between a patient device and an electromedical implant as communication partners is disclosed, wherein a transmitting unit of the patient device is continually switched on and off, so that the transmitting unit is alternately in an activity phase and an activity pause and during its activity pause at least once sends a recognition signal and wherein a receiving unit of the electromedical implant is continually switched on and off so that the receiving unit is alternately in an activity phase and an activity pause and during its activity phase checks whether the transmitting unit is just then in its activity phase and sends a recognition signal, wherein switching on and off of the receiving unit is so effected that an activity phase and an activity pause of the receiving unit together give an overall duration which differs from the overall duration of an activity phase and an activity pause of the transmitting unit so that within a foreseeable period of ti

Abstract: The present invention relates to compounds of the general formula (IV) and (II) and salts and physiologically functional derivatives thereof, wherein X is C—R8 or N; and Z is independently one of the following groups:

Abstract: The present invention relates to furazanopyrazine derivatives of the general formula (I): wherein: R? represents —NR1R2 or —OR9 R? represents —NR5—NR3R4, —NR5—ORb, —O—NR3R4; wherein R1 to R9 in formula (I) represent independently of each other a variety of different substituents comprising alkyl, aryl, aralkyl, alkylaryl, heteroaryl groups and monofunctional moieties.

Abstract: A method and apparatus for data transmission between an electromedical implant having a first transmitter/receiver unit, such as a cardiological implant, and an associated external apparatus having a second transmitter/receiver unit. Data transmission begins with a triggering signal which is sent by the first transmitter/receiver unit in normal operation in predeterminable first intervals. Reception readiness of the first transmitter/receiver unit is maintained after emission of the triggering signal for a second time interval which is shorter than the first time interval.

Abstract: The present invention relates to the use of compounds of the general Formula (XIII): 1

Abstract: An electromedical implant comprising a telemetry device for the exchange of data with an external apparatus is provided. The telemetry device comprising a transmitting device and a receiving device, wherein a separate energy storage means is provided for each of the transmitting device and the receiving device. A method of using an electromedical implant comprising a telemetry device for the exchange of data is also provided.

Abstract: The present invention relates to the use of compounds of the general Formula (I): 1

Abstract: An implantable cardiac pacemaker (1) comprising a control device (2) including a position detector connected to a movement sensor, wherein the position detector has a classification device (23) for recognizing short movements. Preferably the position detector has a memory device (25).

Abstract: A method of after-care in relation to patients with at least one electromedical implant. Data is transmitted from the implant to an external apparatus providing information for an examining clinician on the occasion of an after-care examination of the patient in an after-care arrangement. In an after-care interrogation up-to-date available data of the implant are interrogated and sent for output to corresponding output means, the data interrogation operation being effected prior to the after-care examination automatically after the patient enters an interrogation region of the after-care arrangement.

Abstract: Apparatus for the transmission of at least first data from an electronic device (1; 1′), in particular an electromedical implant such as a cardiac pacemaker, to a monitoring arrangement (38), including at least a first interface device (6; 6′), with at least one input unit for the first data, a control device (5) connected to the first interface device (6; 6′) and a mobile radio device (7) connected to the control device at least for the transmission of the first data to the monitoring arrangement (38) by way of a telecommunication network which is at least in part in the form of a mobile radio network, wherein there is provided at least one second interface device (8) connected to the control device (5) for connecting the control device to a fixed-line telecommunication network.

Abstract: A patient monitoring system (1) is provided with at least one body sensor (2a) for measuring a physiological parameter, as well as with a body signal processing unit (3) connected downstream from the former and/or a therapy device (2) designed to act on the patient (P), and a mobile radiotelephone end unit (7) operable in a cellular mobile radiotelephone network (1B) for transmitting data from the body signal processing unit or the therapy device to a central monitoring station (1C) and/or from the central monitoring station to the therapy device. A base station coordinate memory unit (13; 13′) and a locator unit (12; 12.1′ through 12.3′) connected to the former serves for the rough determination of the location of the patient based on location information obtained from the current base station connection of the mobile radiotelephone end unit in the mobile radiotelephone network.

Abstract: An electromedical implant (1), in particular a cardiac pacemaker, comprising a telemetry device at least for the communication of data to an external apparatus (2), which includes a transmitting device with a transmitter, wherein the transmitter includes an oscillator comprising a first transistor (58) and a resonator (60), and a second transistor (59) forming a buffer stage and an antenna driver.