Patents by Inventor Martin Langner

Martin Langner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing ceftolozane from 7-aminocephalosporanic acid (7-ACA)
    Patent number: 10532058
    Abstract: The present invention relates to a highly convergent method for the synthesis and purification of ceftolozane and intermediates starting from 7-aminocephaiosporanic acid (7-ACA).
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: January 14, 2020
    Assignee: Sandoz AG
    Inventors: Michael Fischer, Wolfgang Felzmann, Ronny Huetz, Martin Langner, Birgit Endl
  • Process for Preparing Ceftolozane from 7-Aminocephalosporanic Acid (7-ACA)
    Publication number: 20180338981
    Abstract: The present invention relates to a highly convergent method for the synthesis and purification of ceftolozane and intermediates starting from 7-aminocephaiosporanic acid (7-ACA).
    Type: Application
    Filed: September 7, 2016
    Publication date: November 29, 2018
    Applicant: Sandoz AG
    Inventors: Michael Fischer, Wolfgang Felzmann, Ronny Huetz, Martin Langner, Birgit Endl
  • Process for the preparation of a chiral compound
    Patent number: 9493428
    Abstract: The present invention relates to a process for the preparation of a compound of formula (V), in particular posaconazole, wherein said process comprises the steps of (1) providing a mixture comprising a compound of formula (IV), a protic solvent system, and a suitable base; and (2) heating the mixture of (1) to obtain a mixture comprising the compound of formula (V).
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: November 15, 2016
    Assignee: SANDOZ AG
    Inventors: Thorsten Wilhelm, Martin Langner
  • Purification of posaconazole and of posaconazole intermediates
    Patent number: 9206146
    Abstract: The present invention relates to a process for the preparation of a hydrogen chloride (HCl) salt of a compound of formula (I) wherein Y1 and Y2 are independently F or Cl, preferably F, said compound of formula (I) containing the cis-isomer and the trans-isomer, wherein the process comprises (1) providing the compound of formula (I) comprised in a first suitable solvent; and (2) treating the compound of formula (I) comprised in the first suitable solvent with HCl comprised in a second suitable solvent to obtain the HCl salt of the compound of formula (I).
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: December 8, 2015
    Assignee: SANDOZ AG
    Inventors: Martin Langner, Dominic De Souza, Abhinay C. Pise, Sachin Bhuta
  • Process for the preparation of chiral triazolones
    Patent number: 9040539
    Abstract: A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y3—NH2; of formula (IIa) 0=C?N—Y0 and/or of formula (IIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: May 26, 2015
    Assignee: SANDOZ AG
    Inventors: Michael Oberhuber, Joerg Salchenegger, Dominic De Souza, Martin Albert, Thorsten Wilhelm, Martin Langner, Hubert Sturm, Hans-Peter Spitzenstaetter
  • PROCESS FOR THE PREPARATION OF A CHIRAL COMPOUND
    Publication number: 20140303184
    Abstract: The present invention relates to a process for the preparation of a compound of formula (V), in particular posaconazole, wherein said process comprises the steps of (1) providing a mixture comprising a compound of formula (IV), a protic solvent system, and a suitable base; and (2) heating the mixture of (1) to obtain a mixture comprising the compound of formula (V).
    Type: Application
    Filed: June 14, 2012
    Publication date: October 9, 2014
    Applicant: SANDOZ AG
    Inventors: Thorsten Wilhelm, Martin Langner
  • PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES
    Publication number: 20130210833
    Abstract: A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y3—NH2; of formula (IIa) 0=C?N—Y0 and/or of formula (IIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).
    Type: Application
    Filed: May 18, 2011
    Publication date: August 15, 2013
    Applicant: Sandoz AG
    Inventors: Michael Oberhuber, Joerg Salchenegger, Dominic De Souza, Martin Albert, Thorsten Wilhelm, Martin Langner, Hubert Sturm, Hans-Peter Spitzenstaetter
  • PURIFICATION OF POSACONAZOLE AND OF POSACONAZOLE INTERMEDIATES
    Publication number: 20130211086
    Abstract: The present invention relates to a process for the preparation of a hydrogen chloride (HCl) salt of a compound of formula (I) wherein Y1 and Y2 are independently F or Cl, preferably F, said compound of formula (I) containing the cis-isomer and the trans-isomer, wherein the process comprises (1) providing the compound of formula (I) comprised in a first suitable solvent; and (2) treating the compound of formula (I) comprised in the first suitable solvent with HCl comprised in a second suitable solvent to obtain the HCl salt of the compound of formula (I).
    Type: Application
    Filed: May 18, 2011
    Publication date: August 15, 2013
    Applicant: SANDOZ AG
    Inventors: Martin Langner, Dominic De Souza, Abhinay C. Pise, Sachin Bhuta
  • Device for opening and closing the panel of a window, door, ventilation hatch, or similar closure
    Patent number: 5271182
    Abstract: A device (16b) for tilting windows, doors, ventilation hatches, or similar closures open, with a motorized transmission-activating mechanism (12b) and a transmission (14b) comprising two back-to-back chains that curve in opposite directions.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: December 21, 1993
    Assignee: Aug.Winkhaus GmbH & Co. KG
    Inventors: Paul Greisner, Dieter Renz, Horst Schwenk, Martin Langner