Abstract: A method of producing a magnetic resonance (MR) image of a region of interest is provided. The method includes the steps of: acquiring an initial MR image of the region of interest, the initial MR image mapping values of an MR-sensitive, physical property at positions over the region; determining a corresponding map of the estimated uncertainties in the values of the MR-sensitive, physical property over the region; and calculating a weighted MR image of the region, the weighted MR image mapping values of a function which combines, at each position of the initial image, the respective value of the MR-sensitive, physical property and the respective estimated uncertainty, the function applying a higher weighting to positions with relatively low estimated uncertainties than to positions with relatively high estimated uncertainties.

Abstract: A method of producing a magnetic resonance (MR) image of a region of interest is provided. The method includes the steps of: acquiring an initial MR image of the region of interest, the initial MR image mapping values of an MR-sensitive, physical property at positions over the region; determining a corresponding map of the estimated uncertainties in the values of the MR-sensitive, physical property over the region; and calculating a weighted MR image of the region, the weighted MR image mapping values of a function which combines, at each position of the initial image, the respective value of the MR-sensitive, physical property and the respective estimated uncertainty, the function applying a higher weighting to positions with relatively low estimated uncertainties than to positions with relatively high estimated uncertainties.

Abstract: A signal receiver is arranged to process a portion of a received signal in each of a plurality of filter branches and to determine a quality metric for each branch. The configuration of a second filter for processing the entirety of the received signal is subsequently performed according to the determined quality metrics.

Abstract: A method of analyzing a sampled signal that is supplied for decimation, wherein the decimation process produces a decimated version of the signal and wherein the method comprises determining an adjustment, if any is required, to the sampling instant of the signal prior to decimation that will cause the frequency responses of the decimated signal and of a main alias to combine constructively at a given frequency.

Abstract: A receiver for acquiring a signal through a propagation channel, the receiver comprising channel estimating means (200) for producing stream of CIR estimates for the channel, a plurality of doppler filtering means (201) for filtering the CIR stream in parallel and selecting means (202) for selecting the output of one of the doppler filtering means for use in recovering said signal.

Abstract: Apparatus comprising a pre-filter rake architecture with various features designed to, in at least some circumstances, to lessen the data processing burden associated with the architecture. In one embodiment, the pre-filter aspect can be disabled.

Abstract: A receiver for acquiring a signal through a propagation channel, the receiver comprising channel estimating means (200) for producing stream of CIR estimates for the channel, a plurality of doppler filtering means (201) for filtering the CIR stream in parallel and selecting means (202) for selecting the output of one of the doppler filtering means for use in recovering said signal.

Abstract: Apparatus comprising a pre-filter rake architecture with various features designed to, in at least some circumstances, to lessen the data processing burden associated with the architecture. In one embodiment, the pre-filter aspect can be disabled.

Abstract: A method of analysing a sampled signal that is supplied for decimation, wherein the decimation process produces a decimated version of the signal and wherein the method comprises determining an adjustment, if any is required, to the sampling instant of the signal prior to decimation that will cause the frequency responses of the decimated signal and of a main alias to combine constructively at a given frequency.

Abstract: A signal receiver is arranged to process a portion of a received signal in each of a plurality of filter branches and to determine a quality metric for each branch. The configuration of a second filter for processing the entirety of the received signal is subsequently performed according to the determined quality metrics.

Abstract: A programmed controller of a gaming console is disclosed. The controller controls play of a game in which a plurality of symbols are selected to form one or more outcomes and selectively operates in a first mode and a second mode of operation. In the first mode of operation a user interface comprises a combination of a touch screen on the display and physical buttons on the gaming apparatus. In the second mode of operation the user interface comprises only physical buttons. Also disclosed is a gaming system including a network and a method of configuring a gaming machine.

Abstract: A method and means enabling identification in an NMR image, being one of a time-sequence of images recording induced changes in pixel values of successive images of a subject (such as post-contrast dynamic images), the contribution to the image arising from the presence within the image subject of a specified tissue (e.g. fat). This identification is done using a statistical measure derived from the dynamic data (e.g. pixel value changes due to contrast agent uptake) taken from a plurality of the separate images forming the time-sequence.

Abstract: A method and apparatus are disclosed for concurrently acquiring two sets of Magnetic Resonance Imaging (MRI) image data during the same image data acquisition interval in which the magnetic field associated with acquisition of the first data set is caused to differ from the magnetic field associated with acquisition of the second data set. The method includes repeatedly changing the magnetic field in a pre-determined manner during the continuous acquisition of image data comprising the two sets. The relationship between the differing magnetic fields, most preferably the relationship between differing gradient fields, is then be employed in conjunction with the first and second data sets to correct image distortions arising in images constructed according to the data in either set alone.

Abstract: There is disclosed a method apparatus for image processing of e.g. MRI images. A method and apparatus is disclosed enabling one to determine if an image contrast/intensity change of a chosen point within an imaged subject volume (e.g. a lesion) is an artefact of motion in the imaged subject. An apparatus and method for fast visual assessment of the imaged subject volume's alignment quality (within a time-sequence of images) is provided, and an interactive display tool enabling effective use of this method is provided.

Abstract: The invention relates to a method for examining at least one object during which properties of the object are detected at different times within a spatial frequency space formed by spatial frequencies. According to the invention, the method is carried out in such a manner that temporally consecutive recordings ensue in overlapping regions of the spatial frequency space and additionally in regions of the spatial frequency space that differ from one another.

Abstract: A multi-game gaming machine includes a gaming console having a first display means on which a simulation of a game can be displayed housed in the console and a second display means also housed in the console. A player input means and a control means are arranged in the console for controlling images displayed on the first video display means. The gaming machine is arranged to allow a player to select a game to be played on the gaming machine from a plurality of different games. The second video display unit displays information pertaining to the multi-game theme or advertisements for games playable on the machine displayed together or in sequence one after another, when the gaming machine is not being played and/or when no game has been selected, and when a game is selected, or played on the machine, the second video display unit displays at least second information associated with the selected game. The present invention provides significant advantages over existing multi-gaming machines.

Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Abstract: The present invention features a multi-bladed cutter and a cradle adapted to grip a tissue sample 10 during cutting. The cutter has a series 4 of juxtaposed blades 5 and the cradle has a series of slits 13 adapted to receive the blades during cutting. The cradle may have opposing curved walls 8,9 which may be brought together to clasp the sample. The apparatus is suitable for cutting tissue such as prostate tissue, which is difficult to section. The apparatus is particularly suited to cutting tissue where chemical fixing is undesirable because nucleic acids are to be sampled from the tissue.

Abstract: The invention provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.