Abstract: There is provided a seal assembly comprising: a first component and a second component spaced apart from the first component so as to define a passage for the transfer of fluid from an inlet of the seal assembly to an outlet of the seal assembly, wherein the first component comprises a concavity at least partially defining the passage, and wherein no part of the second component extends into the portion of the passage bounded by the concavity.

Abstract: A dimmer includes a TRIAC structured to conduct load current during an on phase and not conduct the load current during an off phase; a snubber circuit including a resistor and a capacitor electrically connected to the resistor at a node; and a bidirectional switch structured to transmit a gate current pulse to gate of the TRIAC to switch the TRIAC between the OFF phase and the ON phase, the bidirectional switch including a first MOSFET, a second MOSFET, a first resistor electrically connected to source of the first MOSFET and a second resistor electrically connected to source of the second MOSFET, drain of the first MOSFET being electrically connected to the node of the snubber circuit, and drain of the second MOSFET being electrically connected to the gate of the TRIAC.

Abstract: A dimmer includes a TRIAC, a zero crossing detection circuit coupled to the TRIAC and structured to detect zero crossing of line voltage; a gate control circuit coupled to a gate of the TRIAC and the zero crossing detection circuit, the gate control circuit structured to drive the gate of the TRIAC to switch between an on phase and an off phase; a power supply circuit coupled to the gate control circuit and the zero crossing detection circuit, the power supply circuit structured to supply power to at least the gate control circuit and the zero crossing detection circuit; a snubber circuit coupled to the TRIAC and structured to limit fast transient voltages; and a zero crossing detection improvement circuit comprising a first switch and a second switch and structured to block current from flowing through the power supply circuit and the snubber circuit during the off phase.

Abstract: A method may include applying a protein sequence computation model to generate, based on an input protein sequence, a plurality of proposed protein sequences. A set of possible amino acid residues for each position in at least a portion of an output protein sequence may be identified based on the plurality of proposed protein sequences. A first protein structure having the output protein sequence may be generated by applying a protein structure computation model to select, for each position in at least the portion of the output protein sequence, an amino acid residue from a corresponding set of possible amino acid residues. The protein structure computation model may further determine the conformation of the amino acid residues selected for inclusion in the output protein sequence. In some cases, the first protein structure may be grafted onto a second protein structure to form a third protein structure.

Abstract: A sample cartridge for a chemical processing instrument. The sample cartridge comprises a primary reaction vessel configured to accommodate a fluid sample for processing and configured to receive a lid for closing an open top of the primary reaction vessel, and a reagent vessel configured to receive one or more fluid reagents via an open top of the reagent vessel. The reagent vessel is connected to the primary reaction vessel via a primary reagent channel with a primary reagent valve disposed in the primary reagent channel to control fluid flow through the primary reagent channel. The sample cartridge further comprises a primary pneumatic port in fluid communication with the primary reaction vessel and configured to be connected to a pneumatic module to selectively adjust a pressure within the primary reaction vessel when the lid is closed to draw the fluid contents of the reagent vessel into the primary reaction vessel.

Abstract: In some embodiments, a physical vapor deposition apparatus includes a top flux optimizer configured to be biased. The physical vapor deposition apparatus further includes an intermediate flux optimizer configured to be biased. The top flux optimizer and the intermediate flux optimizer are separated by a first distance. The physical vapor deposition apparatus further includes a bottom flux optimizer configured to be biased. The bottom flux optimizer and the intermediate flux optimizer are separated by a second distance. The physical vapor deposition apparatus further includes a top power source coupled to the top flux optimizer, an intermediate power source coupled to the intermediate flux optimizer, and a bottom power source coupled to the bottom flux optimizer.

Abstract: A wireless transmit/receive unit (WTRU) may be configured to implement layer 1/layer 2 (L1/L2) based inter-cell mobility procedures with reduced latency during handover or other mobility operations. The WTRU may be configured to receive configuration information associated with a plurality of candidate cells. The configuration information may be associated with a physical layer measurement for each candidate cell. The configuration information may include a measurement criteria. The WTRU may be configured to determine a subset of the plurality of candidate cells, with each candidate cell in the subset determined based on the measurement criteria. The WTRU may be configured to send a report indicating the subset. perform a physical layer measurement on the subset, and receive an indication to perform layer handover to a candidate cell of the subset.

Abstract: The present invention generally relates to systems, methods and program products for use with Exchange-Traded Funds (“ETF”) holding one or more secured notes backed by one or more precious metals.

Abstract: A wireless transmit/receive unit (WTRU) may comprise a processor. The processor may be configured to receive (e.g., via broadcast) configuration information indicating a time that a same-PCI satellite switch may occur. In one or more examples, the WTRU may transmit assistance information prior to the same-PCI satellite switch. The assistance information may, for example, include a re-synchronization duration, capabilities to synchronization procedures, and/or a time indication for resuming TX and/or RX. The WTRU may receive configuration information for satellite re-synchronization. The WTRU may perform the same-PCI satellite switch to the second satellite, for example, based on the configuration information indicating the time for the same-PCI satellite switch. In performing the same-PCI satellite switch, the WTRU may start a resynchronization gap, suspend UL TX and/or DL RX, and/or perform re-synchronization procedure(s).

Abstract: Lipid-conjugated oligonucleotide are provided herein that inhibit or reduce expression of target genes. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with an RNAi trigger induced decrease in target gene expression.

Abstract: An aircraft engine incudes: a catalyst, e.g. platinum, applied to turbine blades (580c, 590c) and/or to a catalytic grid downstream of the engine's combustion chamber. An exhaust fluid additive injection system is incorporated upstream of the catalyst via a line 560, in a stator blade within the engine. The catalyst is used to reduce NOx emissions from the engine by a Selective Catalytic Reduction reaction.

Abstract: A method of analysing ions is disclosed comprising: (i) subjecting ions of an analyte molecule to different activation levels at different times so as to cause the ions to have different mobilities at said different times, wherein the activation level is varied in a plurality of cycles, and wherein the activation level is varied between said different levels during each of the cycles. The method uses an ion mobility separator or scanned ion mobility filter to determine the mobilities of the ions for said different activation levels; and correlates the determined mobilities with their respective activation levels so as to thereby obtain a fingerprint for the analyte molecule.

Abstract: A resource manager tracks the amount of available memory for a cluster of machines and for each machine in the cluster. The resource manager receives a reservation request from a job for a graph processing operation. The reservation request specifies an identification of the job, a type of reservation, and an amount of memory requested. The resource manager determines whether to grant the reservation request based on the type of reservation, the amount of memory requested, and the amount of available memory in the cluster or in one or more machines in the cluster. In response to determining to grant the reservation request, the resource manager sends a response to the job indicating an amount of memory reserved and adjusts the amount of available cluster memory and the amount of available machine memory for at least one machine in the cluster based on the amount of memory reserved.

Abstract: Oligonucleotides are provided herein that inhibit KHK expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with KHK expression.

Abstract: Fiber optic networks, optical network units, and methods of configuring a fiber optic network and an optical network unit using a variable ratio coupler are disclosed. In one embodiment, a fiber optic network includes a feeder optical cable. The first optical network unit and the second optical network unit each includes a variable ratio coupler operable to selectively set a split-ratio among a plurality of split-ratios, and a fiber optic transceiver module. The fiber optic network further includes a first drop cable optically coupling the first optical network unit to the feeder optical cable at a first position, and a second drop cable optically coupling the second optical network unit to the feeder optical cable at a second position. A first split-ratio of the first optical network unit is based on the first position and a second split-ratio of the second optical network unit is based on the second position.

Abstract: The present invention relates to a plant-based meat substitute comprising (i) particles comprising a texturized plant protein material, water and a vegetable lipid and (ii) a binding agent comprising, relative to the particles and binding agent,—0.5% to 20% of a high gel strength protein?0.

Abstract: There is provided a seal assembly comprising: a first component and a second component spaced apart from the first component so as to define a passage for the transfer of fluid from an inlet of the seal assembly to an outlet of the seal assembly, wherein the first component comprises a concavity at least partially defining the passage, and wherein no part of the second component extends into the portion of the passage bounded by the concavity.

Abstract: In various embodiments, an automated platform may autonomously move around a site, loading dock, dock leveler, and/or trailer to transport goods. In one or more embodiments, the automated platform may be loaded with goods and, once loaded, navigate a path from a loading area onto a trailer autonomously. In some embodiments, once the automated platform is loaded onto the trailer, the automated platform may utilize hydraulics to extend legs to the ground with enough force so that the automated platform wheels are not touching the ground in the trailer, which stabilizes the automated platform while it is being hauled to a different site. In at least one embodiment, once the trailer is at the different site, the automated platform may autonomously unload itself out of the trailer and navigate over a dock leveler, through the loading dock, and to an unloading area.