Abstract: The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a host strain expressing said modified enzymes and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.

Abstract: An adjustable camshaft for a valve train of an internal combustion engine may include an inner shaft that is rotatable in an outer shaft, a phase shifter by which the outer shaft and/or the inner shaft are/is adjustable in a phase position formed around an axis of rotation, and a bearing portion for bearing the camshaft, via which the phase shifter can be supplied with a pressurizing medium. The inner shaft may comprise an end on which a screw flange is arranged, and a rotor of the phase shifter may be connected to the screw flange. A free end of the inner shaft comprises a duct that coincides with the axis of rotation for at least partially supplying the phase shifter with a pressurizing medium. The duct may extend at least into the bearing portion.

Abstract: The present invention provides an improved biotechnological production of riboflavin (also referred herein as vitamin B2) through modification in the operon containing the riboflavin biosynthetic genes (rib operon), in particular modifications of/in the leader sequences (rib leader) upstream of the corresponding riboflavin biosynthetic genes (rib operon). Furthermore, the present invention relates to genetically engineered microorganisms carrying said modified sequences, processes to generate said modified sequences/microorganisms and the use thereof for production of riboflavin.

Abstract: A connecting arrangement for connecting a shaft to a component is provided. The connecting arrangement includes at least one adapter device with is connectable to the shaft at least in a force-fitting and/or form-fitting manner, and contact surfaces of the component and of the adapter device are configured in a manner matching each other to inhibit rotation relative to one another about a longitudinal axis of the adapter.

Abstract: A multi-modal multi-media air filtration system which can include: a base having one or more connection features and a filter media assembly, the filter media assembly being configured to attach to the base portion at a first end. The filter media assembly can then also include a first filter media extending across a first air flow path and a second filter media extending across a second air flow path. The air filtration assembly can then also include an actuation assembly configured to selectively open or close one of the first air flow path or the second air flow path so as to alternate the degree of filtration passing through the filter media assembly based on the degree of filtration provided by the first or second filter media.

Abstract: A camshaft may have a bearing shaft configured as a hollow shaft in which an inner shaft is disposed concentrically relative to the bearing shaft. The inner shaft may be twistable relative to the bearing shaft. A first cam segment having a first recess for receiving the bearing shaft may be disposed on the bearing shaft, may be rotatable relative to the bearing shaft, and may be connected in a rotationally fixed and axially fixed manner to the inner shaft. A second cam segment having a second recess for receiving the bearing shaft may be disposed on the bearing shaft. The second cam segment may have at least two cam contours and may be fastened on the bearing shaft so that the second cam segment is rotationally fixed to the bearing shaft and arranged in an axially displaceable manner on the bearing shaft.

Abstract: A camshaft for a valve drive of an internal combustion engine having a variable valve opening time may include an outer shaft and an inner shaft that extends through the outer shaft, with the inner shaft being held rotatably with respect to the outer shaft. The camshaft may further include a cam having a multiple-piece configuration, comprising a first part cam and a second part cam. Either the first part cam or the second part cam may be connected fixedly to the outer shaft so as to rotate with it, and the other part cam may be connected fixedly to the inner shaft so as to rotate with it. The camshaft may also include a bearing inner ring of a shaft bearing that is held on the outer shaft, with one of two second part cams comprising an axial attachment that forms at least one part of the bearing inner ring.

Abstract: A camshaft adjusting device of a drive, such as a motor vehicle drive, for example, for adjusting a phase position of a cam segment may include a camshaft and a phase shifter that is operatively connected to the camshaft. The camshaft may comprise a shaft segment including an inner shaft and an outer shaft at least partially surrounding the inner shaft. The camshaft adjusting device may further comprise a drive segment for driving the shaft segment and a cam segment that is connected in a form-fitting and/or force-fitting manner to the outer shaft. The phase shifter may comprise a rotor element and a stator element. A compensating element for compensating for part tolerances between the camshaft and the phase shifter can be disposed at least in sections between the rotor element and the drive segment.

Abstract: A joint arrangement includes comprising a joint, a nut and an adapter unit. The joint has an inner hub, an outer hub, balls and a cage with recesses for the balls. The inner hub has a recess with an inner toothing for receiving a first shaft. A cavity of the joint arrangement located around the balls is closed on two end sides by a respective sealing device. The adapter unit includes a first adapter portion and a second adapter portion which cooperate to transmit torque across the joint arrangement to or from a second shaft.

Abstract: A nut with a nut body with several clamping segments at an upper end face of the nut body has an internal thread with at least a first portion and a second portion. The first portion has a first thread pitch that ends at a lower end face of the nut body opposite the upper end face. The second portion has a second thread pitch which is smaller than the first thread pitch. The internal thread may include a third portion having a third thread pitch at least partially located at the clamping segments, where the second portion is between the first and third portions. The third thread pitch may be the same as the first thread pitch.

Abstract: An adjustable camshaft may include an outer shaft that is hollow and an inner shaft received in the outer shaft and rotatable in the outer shaft. The inner shaft may include a cavity into which oil can be applied. At least a first radial opening may be configured in the outer shaft and at least a second radial opening may be configured in the inner shaft. Thus oil can flow between the cavity and an outside of the outer shaft during overlap of the first radial opening and the second radial opening. The first radial opening on an inside of the outer shaft may have a greater cross-section than on the outside of the outer shaft.

Abstract: A measuring device having at least one at least approximately tubular probe device, by means of which an impact pressure, a total pressure or a dynamic pressure of a flow can be determined, and which is designed movable at least between a first operating state and a second operating state, where the probe device can be moved by an actuating unit in a controlled manner between the first operating state and the second operating state and held in said states.

Abstract: An adjustable camshaft can be used in valve drives of internal combustion engines, amongst other places. The adjustable camshaft may include an outer shaft and an inner shaft that is concentric with and rotatably supported in the outer shaft. A cam having a cam bore may be rotatably supported on an outer surface of the outer shaft so as to form a slide bearing gap between the cam and the outer shaft. The cam may be rotatably-fixed to the inner shaft so that the inner shaft and the cam rotate with one another. Furthermore, the adjustable camshaft may include an oil channeling groove disposed beneath the cam in the outer surface of the outer shaft. In many cases, at least one side of the oil channeling groove may be exposed such that it extends beyond the slide bearing gap and the cam.

Abstract: An adjustable camshaft for a valve train of an internal combustion engine may include an inner shaft that is rotatable in an outer shaft, a phase shifter by which the outer shaft and/or the inner shaft are/is adjustable in a phase position formed around an axis of rotation, and a bearing portion for bearing the camshaft, via which the phase shifter can be supplied with a pressurizing medium. The inner shaft may comprise an end on which a screw flange is arranged, and a rotor of the phase shifter may be connected to the screw flange. A free end of the inner shaft comprises a duct that coincides with the axis of rotation for at least partially supplying the phase shifter with a pressurizing medium. The duct may extend at least into the bearing portion.

Abstract: A coarse-fine two-stage leak detection is carried out on sealed, filled containers loaded into container holders or “pucks”. Failure of the first, coarse leak detection stage, e.g. a pressure-course or impedance or laser-absorption based leak detection stage, causes containers to be rejected together with their corresponding container holders. These are then separated, and the container holder is cleaned and dried before being returned to the system. Any leaking product from inside a grossly leaking container is thus retained within the container holder, thus reducing contamination of subsequent containers and their container holders, preventing such contamination from reaching the fine leak detection stage, e.g. a mass-spectrometer-based leak detection stage.

Abstract: The invention relates to a camshaft comprising a support shaft formed as a hollow shaft. An inner shaft is arranged concentrically in the interior of the support shaft, wherein the inner shaft is rotatable relative to the support shaft. There is arranged on the support shaft a first cam segment with a first recess for receiving the support shaft, which cam segment is rotatable with respect to the support shaft and is connected in a rotationally conjoint manner to the inner shaft via a first opening in the support shaft. The first cam segment has at least two cam contours. The connection between the inner shaft and the first cam segment is furthermore configured such that the first cam segment is axially displaceable relative to the inner shaft and to the support shaft.

Abstract: A connecting arrangement for connecting a shaft to a component is provided. The connecting arrangement includes at least one adapter device with is connectable to the shaft at least in a force-fitting and/or form-fitting manner, and contact surfaces of the component and of the adapter device are configured in a manner matching each other to inhibit rotation relative to one another about a longitudinal axis of the adapter.

Abstract: The invention pertains to a device for 3-dimensionally positioning a coupling component, which forms part of an actuator-driven coupling structure, wherein said device comprises at least a first coupling element that extends in a first longitudinal direction and can be bidirectionally displaced along its first longitudinal direction by means of a first actuator, a second coupling element that extends in a second longitudinal direction and can be bidirectionally displaced along its second longitudinal direction, which extends orthogonal to the first longitudinal direction, by means of a second actuator, and a lever with a longitudinal lever direction that is mounted pivotably about a pivoting axis, which divides the lever into a work arm and a power arm.

Abstract: A drive arrangement for a drive train of a vehicle is disclosed. In one aspect, the drive arrangement includes at least one transmission element configured to transmit a force and/or a torque and at least one joint. The transmission element and the joint are configured to be connected reversibly in a force transmitting manner and/or in a torque-transmitting manner.

Abstract: An adjustable camshaft for a valve drive of an internal combustion engine may include an inner shaft extending through an outer shaft with a cam element disposed on the outer shaft. The cam element may be connected rotationally conjointly to the inner shaft. The cam element may have a shaft passage with an internal bearing surface, which, together with a bearing surface on an outer side of the outer shaft, forms a plain bearing arrangement for the rotatable arrangement of the cam element on the outer shaft. The bearing surface on the outer side of the outer shaft and/or the internal bearing surface of the shaft passage of the cam element may include one or more sections with a spherical shape.