Patents by Inventor Martin Leon Yarmush

Martin Leon Yarmush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions, methods, and devices for treating disease
    Patent number: 10363276
    Abstract: Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem cell conditioned media.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: July 30, 2019
    Assignees: The General Hospital Corporation, Massachusetts Institute of Technology
    Inventors: Martin Leon Yarmush, Biju Parekkadan
  • COMPOSITIONS, METHODS, AND DEVICES FOR TREATING DISEASE
    Publication number: 20160331784
    Abstract: Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem cell conditioned media.
    Type: Application
    Filed: December 11, 2015
    Publication date: November 17, 2016
    Applicants: The General Hospital Corporation d/b/a Massachusetts General Hospital, Massachusetts Institute of Technology
    Inventors: Martin Leon Yarmush, Biju Parekkadan
  • ANTI-INFLAMMATORY FACTORS
    Publication number: 20130052198
    Abstract: The present invention provides particular anti-inflammatory factors, compositions containing them, methods of making, identifying, and/or characterizing them, and methods of using them. In some embodiments, provided factors are expressed by human bone marrow stromal cells (MSC). In some embodiments, provided factors are characterized by an ability, when contacted with mammalian leukocytes in culture, to alter production of at least one inflammatory or anti-inflammatory agent by the mammalian leukocytes. In some embodiments, provided factors include GALNT1 polypeptides, LGALS3BP polypeptides, MFAP5 polypeptides, PENK polypeptides and/or HAPLN1 polypeptides. In some embodiments, provided factors are useful in the inhibition of inflammatory agents, in the promotion of anti-inflammatory agents, and/or for the treatment of subjects suffering from or susceptible to a disease, disorder or condition characterized by inflammation.
    Type: Application
    Filed: March 29, 2011
    Publication date: February 28, 2013
    Applicants: THE GENERAL HOSPITAL CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: John Miles Milwid, Biju Parekkadan, Martin Leon Yarmush, Matthew LI
  • HEMATOPOIETIC STROMAL PROGENITOR CELLS AND USES THEREOF
    Publication number: 20120177618
    Abstract: The invention provides compositions and methods for modulating disease using hematopoietic stromal progenitor cells derived from hematopoietic tissues. The invention further provides methods for isolating, storing and culturing hematopoietic stromal progenitor cells.
    Type: Application
    Filed: July 14, 2010
    Publication date: July 12, 2012
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Biju Parekkadan, John Miles Milwid, Martin Leon Yarmush
  • METHODS AND COMPOSITIONS FOR MODULATING IMMUNOLOGICAL TOLERANCE
    Publication number: 20110150845
    Abstract: The invention provides compositions and methods for modulating immune responses using mesenchymal stem cells. The invention further provides methods for inducing tolerance to self antigens using mesenchymal stem cells.
    Type: Application
    Filed: May 1, 2009
    Publication date: June 23, 2011
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Biju Parekkadan, Martin Leon Yarmush, Shannon J. Turley