Patents by Inventor Martin Leonard Ashdown
Martin Leonard Ashdown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10714208Abstract: The present invention relates to computer-implemented methods and system for analysing a biomarker which cycles in a subject. In some other aspects, the present invention relates to analysing a biomarker which at least initially increases or decreases in amount in a subject following a treatment for a disease. In further aspects, the present invention relates to computer-implemented methods and systems for determining a preferred time to administer a therapy to treat a disease in a subject. The present invention also relates to computer program product to implement the methods. Further, the present invention relates to methods of determining the timing of treating a disease in a subject in which the immune system is cycling.Type: GrantFiled: January 12, 2016Date of Patent: July 14, 2020Assignee: BIOTEMPUS PTY LTDInventors: Martin Leonard Ashdown, Andrew Robinson
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Patent number: 9268908Abstract: The present invention relates to computer-implemented methods and system for analyzing a biomarker which cycles in a subject. In some other aspects, the present invention relates to analyzing a biomarker which at least initially increases or decreases in amount in a subject following a treatment for a disease. In further aspects, the present invention relates to computer-implemented methods and systems for determining a preferred time to administer a therapy to treat a disease in a subject. The present invention also relates to computer program product to implement the methods. Further, the present invention relates to methods of determining the timing of treating a disease in a subject in which the immune system is cycling.Type: GrantFiled: January 10, 2013Date of Patent: February 23, 2016Assignee: BIOTEMPUS LIMITEDInventors: Martin Leonard Ashdown, Andrew Robinson
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Patent number: 9239904Abstract: The present invention relates to computer-implemented methods and system for analyzing a biomarker which cycles in a subject. In some other aspects, the present invention relates to analyzing a biomarker which at least initially increases or decreases in amount in a subject following a treatment for a disease. In further aspects, the present invention relates to computer-implemented methods and systems for determining a preferred time to administer a therapy to treat a disease in a subject. The present invention also relates to computer program product to implement the methods. Further, the present invention relates to methods of determining the timing of treating a disease in a subject in which the immune system is cycling.Type: GrantFiled: March 21, 2013Date of Patent: January 19, 2016Assignee: BIOTEMPUS LIMITEDInventors: Martin Leonard Ashdown, Andrew Robinson
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Publication number: 20150377882Abstract: Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.Type: ApplicationFiled: September 3, 2015Publication date: December 31, 2015Inventor: Martin Leonard Ashdown
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Patent number: 9122778Abstract: The present invention relates to computer-implemented methods and system for analyzing a biomarker which cycles in a subject. In some other aspects, the present invention relates to analyzing a biomarker which at least initially increases or decreases in amount in a subject following a treatment for a disease. In further aspects, the present invention relates to computer-implemented methods and systems for determining a preferred time to administer a therapy to treat a disease in a subject. The present invention also relates to computer program product to implement the methods. Further, the present invention relates to methods of determining the timing of treating a disease in a subject in which the immune system is cycling.Type: GrantFiled: May 27, 2010Date of Patent: September 1, 2015Assignee: BIOTEMPUS LIMITEDInventors: Martin Leonard Ashdown, Andrew Robinson
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Publication number: 20150110805Abstract: Numerous diseases have been linked to the production of effector cells. The present invention relates to the realization that effector cells are cycling in these diseases. In addition, the present invention relates to the determination that regulator cells are cycling in degenerative diseases. Based on these realizations, the present invention provides methods for treating conditions such as autoimmune diseases, degenerative diseases, and graft-versus-host disease. The present invention also relates to methods of determining when therapy should be administered to a patient.Type: ApplicationFiled: December 22, 2014Publication date: April 23, 2015Inventors: Martin Leonard Ashdown, Luisa Maria Ashdown
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Publication number: 20140065644Abstract: Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.Type: ApplicationFiled: October 25, 2013Publication date: March 6, 2014Applicant: ImmunAid Pty. Ltd.Inventor: Martin Leonard Ashdown
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Publication number: 20140051100Abstract: Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.Type: ApplicationFiled: October 24, 2013Publication date: February 20, 2014Applicant: ImmunAid Pty. Ltd.Inventor: Martin Leonard Ashdown
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Patent number: 8524651Abstract: Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.Type: GrantFiled: February 14, 2012Date of Patent: September 3, 2013Assignee: ImmunAid Pty Ltd.Inventor: Martin Leonard Ashdown
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Publication number: 20120220640Abstract: The present invention relates to computer-implemented methods and system for analysing a biomarker which cycles in a subject. In some other aspects, the present invention relates to analysing a biomarker which at least initially increases or decreases in amount in a subject following a treatment for a disease. In further aspects, the present invention relates to computer-implemented methods and systems for determining a preferred time to administer a therapy to treat a disease in a subject. The present invention also relates to computer program product to implement the methods. Further, the present invention relates to methods of determining the timing of treating a disease in a subject in which the immune system is cycling.Type: ApplicationFiled: May 27, 2010Publication date: August 30, 2012Applicant: IMMUNAID PTY LTDInventors: Martin Leonard Ashdown, Andrew Robinson
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Publication number: 20120156225Abstract: Numerous diseases have been linked to the production of regulator cells. The present invention relates to the observation that the immune system is cycling in these diseases. Based on these observations, the present invention provides methods for treating diseases such as cancer and a HIV infection. The present invention also relates to methods of determining when a therapy to treat a disease characterized by the production of regulator cells should be administered to a patient.Type: ApplicationFiled: February 14, 2012Publication date: June 21, 2012Applicant: IMMUNAID PTY LTDInventor: Martin Leonard ASHDOWN
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Publication number: 20090041760Abstract: The present inventor has noted that at least two populations of immune cells are produced in response to retroviruses which infect mammals. More particularly, the immune system of a mammal infected with a retrovirus is capable of mounting an immune response against the virus through a group of cells herein generally referred to as “effector cells”, however, a second population of cells are also produced which regulate the “effector cells”, herein generally referred to as “regulator cells” (or suppressor cells), limiting the mammal's ability to effectively control or eradicate the retroviral infection. Accordingly, the present invention utilizes these observations to provide methods for treating a mammal with a retroviral infection.Type: ApplicationFiled: September 18, 2008Publication date: February 12, 2009Inventor: Martin Leonard ASHDOWN
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Publication number: 20080248022Abstract: Numerous diseases have been linked to the production of effector cells. The present invention relates to the realization that effector cells are cycling in these diseases. In addition, the present invention relates to the determination that regulator cells are cycling in degenerative diseases. Based on these realizations, the present invention provides methods for treating conditions such as autoimmune diseases, degenerative diseases, and graft-versus-host disease. The present invention also relates to methods of determining when therapy should be administered to a patient.Type: ApplicationFiled: September 8, 2005Publication date: October 9, 2008Applicant: IMMUNAID PTY LTDInventors: Martin Leonard Ashdown, Maria Luisa Ashdown
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Publication number: 20030228320Abstract: The present inventor has noted that at least two populations of immune cells are produced in response to retroviruses which infect mammals. More particularly, the immune system of a mammal infected with a retrovirus is capable of mounting an immune response against the virus through a group of cells herein generally referred to as “effector cells”, however, a second population of cells are also produced which regulate the “effector cells”, herein generally referred to as “regulator cells” (or suppressor cells), limiting the mammal's ability to effectively control or eradicate the retroviral infection. Accordingly, the present invention utilizes these observations to provide methods for treating a mammal with a retroviral infection.Type: ApplicationFiled: February 18, 2003Publication date: December 11, 2003Inventor: Martin Leonard Ashdown
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Patent number: 6642012Abstract: Method for determining a cellular function or change in cellular function by contacting a sample of cells or a component of cells with an activating agent, directing a beam of infrared light at the sample of cells or a component of the cells, analyzing the infrared spectrum of the sample at at least one range of frequencies and ascertaining whether at least one change in the spectral characteristics has occurred due to activation of the cells or a change in the cellular component, that can be correlated to the cellular function or the change in cellular function by the activating agent and determining the cellular function therefrom.Type: GrantFiled: August 26, 1998Date of Patent: November 4, 2003Inventor: Martin Leonard Ashdown