Abstract: Variants of chymosin with improved milk-clotting properties are disclosed.

Abstract: An adjustable seal system, seal component for use in the system, and method are provided for forming a sealing interface between a residual limb and a prosthetic socket. The seal component is selectively placed over the outer surface of a suspension liner including a plurality of seal bands, which the seal component may removably and securely engage.

Abstract: An adjustable socket system includes first and second shell components and first and second longitudinal supports connected to a base. The socket system is movable between an open configuration to loosen the fit of the socket system, and a closed configuration to secure the fit of the socket system on residual limb received therein. A tightening system includes a tensioning unit having a handle defining a moment arm rotatable about a rotation axis, and a tensioning element operatively coupled to the handle via a movable connection point located and protected between the first shell component and the first support and to the shell components via a control point. Rotation of the handle displaces the movable connection point and the tensioning element relative to the control point to move the socket system to the closed configuration.

Abstract: A main tube (2) has a first lumen (3) with a proximal end (5) and a distal end (6) to be placed inside a body cavity. An outer wall (7) encloses the first lumen and a dedicated camera lumen (4). A camera module is arranged at the distal end of the first lumen. An image transmission cable attached to the camera module extends through the camera lumen to connect to an image display device. A separately manufactured tip housing (20) is mounted on the main tube at the distal end of the first lumen. The tip housing forms a tip extension (23) of the first lumen and a tip extension (24) of the camera lumen. The tip extension of the first lumen has an open end (25), and the camera module is arranged at least partly in the tip extension of the camera lumen.

Abstract: Variants of chymosin with improved milk-clotting properties are disclosed.

Abstract: The tube has a first lumen with a proximal end and an open distal end to be placed inside a body cavity. An outer wall encloses the first lumen and a camera lumen. A camera module (10) is arranged in the camera lumen at a distal end thereof so that the camera module is positioned adjacent the distal end of the first lumen. An image transmission cable (13) attached to the camera module extends through the camera lumen to connect to an image display device. The camera module is fixed in the camera lumen by means of a camera housing (14) including a tubular housing part (17) surrounding the camera module and a distal end wall (18). The tubular housing part and the distal end wall are integrally moulded and form one single housing element (19). The tubular housing part fits tightly into the camera lumen of the tube.

Abstract: An adjustable socket system includes first and second shell components and first and second longitudinal supports connected to a base. The socket system is movable between an open configuration to loosen the fit of the socket system, and a closed configuration to secure the fit of the socket system on residual limb received therein. A tightening system includes a tensioning unit having a handle defining a moment arm rotatable about a rotation axis, and a tensioning element operatively coupled to the handle via a movable connection point located and protected between the first shell component and the first support and to the shell components via a control point. Rotation of the handle displaces the movable connection point and the tensioning element relative to the control point to move the socket system to the closed configuration.

Abstract: A medical device including a main tube having an outer wall, a first lumen, and a camera lumen; a tip housing separately manufactured from the main tube and including a tubular housing part extending from a proximal end to a distal end, a first lumen extension, a camera lumen extension, the tubular housing part enclosing the first lumen extension and the camera lumen extension, and the proximal end of the tip housing mounted at the distal end of the main tube; a camera module; a camera housing positioned in the camera lumen extension and affixing the camera module to the tip housing, the camera housing having a tubular housing part having an inner face; and a support structure including a tubular end part having an outer face adhesively bonded to the inner face of the tubular housing part to secure the camera module to the camera housing.

Abstract: A prosthetic attachment system includes an insert arranged for connection to a prosthetic liner, and an attachment unit arranged for connection to a distal end of a prosthetic socket. The attachment unit comprises a body defining an axis and a central opening for selectively receiving the insert. The body carries a plurality of locking elements that are distributed circumferentially about the axis and radially repositionable relative to the axis. A release mechanism is slidably positioned on an outer surface of the body to move the prosthetic attachment system between a locked configuration in which the locking elements are radially repositioned to lock the insert in the central opening of the body and an unlocked configuration in which the insert is released from the central opening.

Abstract: A prosthetic attachment system includes an insert arranged for connection to a prosthetic liner, and an attachment unit arranged for connection to a distal end of a prosthetic socket. The attachment unit comprises a body defining an axis and a central opening for selectively receiving the insert. The body carries a plurality of locking elements that are distributed circumferentially about the axis and radially repositionable relative to the axis. A release mechanism is slidably positioned on an outer surface of the body to move the prosthetic attachment system between a locked configuration in which the locking elements are radially repositioned to lock the insert in the central opening of the body and an unlocked configuration in which the insert is released from the central opening.

Abstract: Variants of chymosin with improved milk-clotting properties are disclosed.

Abstract: An adjustable seal system includes a seal component having a body having an outer surface defining a socket sealing portion arranged to engage and form an airtight seal with an interior surface of a prosthetic socket. The inner surface of the body defines a liner sealing portion arranged to frictionally engage and seal with an outer surface of a prosthetic liner. The liner sealing portion defines a sealing length extending in a proximal direction from an end of the socket sealing portion and terminating at a proximal edge on the body. The length of the liner sealing portion is between about 25 mm and about 35 mm and is selected in relation to the socket sealing portion to vary tractions at the inner and outer surfaces of the seal component.

Abstract: Variants of chymosin with improved milk clotting properties.

Abstract: An adjustable seal system includes a seal component having a body having an outer surface defining a socket sealing portion arranged to engage and form an airtight seal with an interior surface of a prosthetic socket. The inner surface of the body defines a liner sealing portion arranged to frictionally engage and seal with an outer surface of a prosthetic liner. The liner sealing portion defines a sealing length extending in a proximal direction from an end of the socket sealing portion and terminating at a proximal edge on the body. The length of the liner sealing portion is between about 25 mm and about 35 mm and is selected in relation to the socket sealing portion to vary tractions at the inner and outer surfaces of the seal component.

Abstract: The present invention relates to methods for encapsulating a bioactive agent such as a microorganism, methods for making a modified food, feed, cosmetic, plant health, seed health or pharmaceutical product comprising heteropolymer particles encapsulating a bioactive agent such as a microorganism, compositions and modified products comprising heteropolymer particles of a phenolic compound and a protein, and a bioactive agent encapsulated therein obtainable by such methods. Also provided is a method for delivering a bioactive agent to a subject, comprising administering to said subject the modified food, feed, cosmetic, plant health, seed health or pharmaceutical product described herein.

Abstract: The present invention relates to methods for producing dairy food products modified with respect to their firmness and/or gelation time comprising cross-linked protein compounds and to methods for modifying said properties of said dairy food products, as well as to said modified dairy food products obtainable or obtained by such methods. Modification is achieved by in situ generation of H2O2 via carbohydrate oxidase, preferably cellobiose oxidase (EC 1.1.99.18), and cross-linking protein-tyrosine residues in a reaction using H202 via peroxidase (EC 1.11.1.7). Adding small phenolic compounds such as preferably p-coumaric acid or vanillin allows better control of the cross-linking reaction.

Abstract: A prosthetic interface includes a body portion having an open proximal end and a closed distal end including a distal cup. The body portion includes a membrane component having a flexible configuration defining an internal flow space extending along a length of the membrane component between an inner side arranged to face a skin surface of a residual limb and an outer side arranged to face away from the skin surface. At least one material coating is selectively applied to the membrane component that interacts with at least one of the membrane component and the distal cup to define at least one breathable region along the inner side that allows fluid flow between the internal flow space and the residual limb, and at least one impermeable region along the outer side that allows for vacuum suspension between the prosthetic interface and a prosthetic socket.

Abstract: Variants of chymosin with improved milk-clotting properties are disclosed.

Abstract: A prosthetic interface includes a body portion having an open proximal end and a closed distal end including a distal cup. The body portion includes a membrane component having a flexible configuration defining an internal flow space extending along a length of the membrane component between an inner side arranged to face a skin surface of a residual limb and an outer side arranged to face away from the skin surface. At least one material coating is selectively applied to the membrane component that interacts with at least one of the membrane component and the distal cup to define at least one breathable region along the inner side that allows fluid flow between the internal flow space and the residual limb, and at least one impermeable region along the outer side that allows for vacuum suspension between the prosthetic interface and a prosthetic socket.

Abstract: A method for making a new food, feed or pharmaceutical product comprising addition of a composition comprising cross-linked, via intermolecular covalent isopeptide bonds, casein glycomacropeptide (CGMP) oligomers (CGMP oligomers) to the product.