Patents by Inventor Martin MacPhee

Martin MacPhee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060115376
    Abstract: Methods are disclosed for sterilizing preparations of digestive enzymes to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. These methods involve sterilizing preparations of digestive enzymes, such as trypsin, ?-galactosidase and iduronate-2-sulfatase, with irradiation.
    Type: Application
    Filed: January 9, 2006
    Publication date: June 1, 2006
    Inventors: David Mann, Wilson Burgess, William Drohan, Yuri Griko, Martin MacPhee
  • Publication number: 20050202003
    Abstract: Methods are disclosed for sterilizing preparation of monoclonal immunoglobulins to reduce the level of active biological contaminants such as viruses, bacteria, yeasts, molds, mycoplasmas, prions and parasites.
    Type: Application
    Filed: April 28, 2005
    Publication date: September 15, 2005
    Inventors: Teri Grieb, Wilson Burgess, William Drohan, Ren-Yo Forng, Martin MacPhee, David Mann, Anna McBain
  • Patent number: 6908591
    Abstract: Methods are disclosed for sterilizing tissue to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria, (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, spores, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing one or more tissues with irradiation.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: June 21, 2005
    Assignee: Clearant, Inc.
    Inventors: Martin MacPhee, Glenn Calvert, Tom Lynch, Randall S. Kent, David Mann, Wilson Burgess, Shirley Miekka, William N. Drohan
  • Publication number: 20050106728
    Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible, alone or in combination, for TSEs. These methods involve the use of stabilizer mixtures in methods of sterilizing biological materials with irradiation.
    Type: Application
    Filed: October 21, 2004
    Publication date: May 19, 2005
    Inventors: Wilson Burgess, William Drohan, Martin MacPhee, David Mann
  • Publication number: 20050069453
    Abstract: Methods are disclosed for sterilizing preparations of urokinase to reduce the level therein of one or more active biological contaminants or pathogens, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia and rickettsias), yeasts, molds, fungi, single or multicellular parasites, and prions or similar agents responsible, alone or in combination, for TSEs. These methods involve sterilizing preparations of urokinase with irradiation.
    Type: Application
    Filed: September 29, 2003
    Publication date: March 31, 2005
    Inventors: Ren-Yo Forng, David Mann, Wilson Burgess, William Drohan, Martin MacPhee, Shirley Miekka
  • Publication number: 20050048637
    Abstract: Methods are disclosed for sterilizing preparations of glycosidases to reduce the level therein of one or more active biological contaminants or pathogens, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, prions or similar agents responsible, alone or in combination, for TSEs. These methods involve sterilizing preparations of glycosidases, such as alpha-glucosidase or alpha-galactosidase, with irradiation.
    Type: Application
    Filed: May 7, 2004
    Publication date: March 3, 2005
    Inventors: William Drohan, Wilson Burgess, David Mann, Martin MacPhee
  • Publication number: 20050047958
    Abstract: Methods are disclosed for sterilizing preparations of digestive enzymes to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. These methods involve sterilizing preparations of digestive enzymes, such as trypsin, ?-galactosidase and iduronate-2-sulfatase, with irradiation.
    Type: Application
    Filed: May 7, 2004
    Publication date: March 3, 2005
    Inventors: David Mann, Wilson Burgess, William Drohan, Yuri Griko, Martin MacPhee
  • Publication number: 20040091388
    Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible, alone or in combination, for TSEs.
    Type: Application
    Filed: October 29, 2003
    Publication date: May 13, 2004
    Applicant: Clearant, Inc.
    Inventors: Martin MacPhee, William N. Drohan, Randall S. Kent, Tom Lynch, Glenn Calvert, Shirley Miekka, David Mann, Wilson Burgess
  • Publication number: 20040033160
    Abstract: Methods are disclosed for sterilizing tissue to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria, (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, spores, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing one or more tissues with irradiation.
    Type: Application
    Filed: July 18, 2002
    Publication date: February 19, 2004
    Inventors: Martin MacPhee, Glenn Calvert, Tom Lynch, Randall S. Kent, David Mann, Wilson Burgess, Shirley Miekka, William N. Drohan
  • Patent number: 6682695
    Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible, alone or in combination, for TSEs.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: January 27, 2004
    Assignee: Clearant, Inc.
    Inventors: Martin MacPhee, William N. Drohan, Randall S. Kent, Tom Lynch, Glenn Calvert, Shirley Miekka, David Mann, Wilson Burgess
  • Publication number: 20040013562
    Abstract: Methods are disclosed for sterilizing biological products to reduce the level of active biological contaminants such as viruses, bacteria, yeasts, molds, mycoplasmas and parasites.
    Type: Application
    Filed: July 18, 2002
    Publication date: January 22, 2004
    Inventors: Wilson Burgess, David Mann, Martin MacPhee, Randall Kent, William Drohan
  • Publication number: 20040013561
    Abstract: Methods are disclosed for sterilizing biological products to reduce the level of active biological contaminants such as viruses, bacteria, yeasts, molds, mycoplasmas and parasites.
    Type: Application
    Filed: July 18, 2002
    Publication date: January 22, 2004
    Inventors: David Mann, Wilson Burgess, Randall S. Kent, Martin MacPhee, William N. Drohan
  • Publication number: 20030161753
    Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible, alone or in combination, for TSEs.
    Type: Application
    Filed: July 18, 2002
    Publication date: August 28, 2003
    Inventors: Martin MacPhee, William N. Drohan, Randall S. Kent, Tom Lynch, Glenn Calvert, Shirley Miekka, David Mann, Wilson Burgess
  • Publication number: 20030012779
    Abstract: Methods are disclosed for sterilizing preparation of monoclonal immunoglobulins to reduce the level of active biological contaminants such as viruses, bacteria, yeasts, molds, mycoplasmas, prions and parasites.
    Type: Application
    Filed: June 14, 2001
    Publication date: January 16, 2003
    Applicant: CLEARANT, INC.
    Inventors: Teri Grieb, Wilson H. Burgess, William N. Drohan, Ren-Yo Forng, Martin MacPhee, David M. Mann, Anna McBain