Patents by Inventor Martin Mandel

Martin Mandel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5633412
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: May 27, 1997
    Assignee: Virginia Tech Intellectual Properties
    Inventors: Tomas Hudlicky, Martin Mandel
  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5602263
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 11, 1997
    Assignee: Virginia Tech Intellectual Properties
    Inventors: Tomas Hudlicky, Martin Mandel
  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5602287
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 11, 1997
    Assignee: Virginia Tech Intellectual Properties
    Inventors: Tomas Hudlicky, Martin Mandel
  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5600014
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 4, 1997
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Tomas Hudlicky, Martin Mandel
  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5578738
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: November 26, 1996
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Tomas Hudlicky, Martin Mandel
  • Syntheses of D-chiro-3-inosose and (+)-D-chiro inositol
    Patent number: 5563281
    Abstract: There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon 12 made by reacting a protected diol (acetonide) with permaganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon 12 and compounds derived therefrom.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: October 8, 1996
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Tomas Hudlicky, Martin Mandel
  • Method for preparing erythruronolactone
    Patent number: 5442079
    Abstract: There are described improved processes for the synthesis of a desired lactone useful as a synthon, the improved processes comprising oxidizing a protected arene diol with permanganate and periodate or subjecting a substituted epoxydiol to periodate oxidation to yield the desired lactone.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: August 15, 1995
    Assignee: Virginia Polytechnic Institute and State University
    Inventors: Tomas Hudlicky, Martin Mandel