Patents by Inventor Martin Maria FABANI
Martin Maria FABANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11891660Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: GrantFiled: November 17, 2022Date of Patent: February 6, 2024Assignee: Singular Genomics Systems, Inc.Inventors: Eli N. Glezer, Martin Maria Fabani, Sabrina Shore, Daan Witters
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Publication number: 20230203576Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: November 17, 2022Publication date: June 29, 2023Inventors: Eli N. GLEZER, Martin Maria FABANI, Timothy LOONEY, Sabrina SHORE, Ryan SHULTZABERGER, Daan WITTERS
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Patent number: 11519029Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: GrantFiled: May 29, 2022Date of Patent: December 6, 2022Assignee: Singular Genomics Systems, Inc.Inventors: Eli N. Glezer, Martin Maria Fabani, Sabrina Shore, Daan Witters
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Publication number: 20220325341Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: May 29, 2022Publication date: October 13, 2022Inventors: Eli N. GLEZER, Martin Maria FABANI, Sabrina SHORE, Daan WITTERS
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Publication number: 20220282324Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: April 22, 2022Publication date: September 8, 2022Inventors: Eli N. GLEZER, Martin Maria FABANI, Timothy LOONEY, Sabrina SHORE, Ryan SHULTZABERGER, Daan WITTERS
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Patent number: 11365445Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: GrantFiled: October 13, 2021Date of Patent: June 21, 2022Assignee: Singular Genomics Systems, Inc.Inventors: Eli N. Glezer, Martin Maria Fabani, Sabrina Shore, Daan Witters
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Patent number: 11359238Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: GrantFiled: March 5, 2021Date of Patent: June 14, 2022Inventors: Eli N. Glezer, Martin Maria Fabani, Sabrina Shore, Daan Witters
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Publication number: 20220119878Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: October 13, 2021Publication date: April 21, 2022Inventors: Eli N. Glezer, Martin Maria Fabani, Timothy Looney, Sabrina Shore, Ryan Shultzaberger, Daan Witters
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Publication number: 20220106636Abstract: Provided herein are methods of making, amplifying, and sequencing tagged nucleic acid complements, compositions including interposing oligonucleotide barcodes, and kits useful in obtaining long-range sequence data.Type: ApplicationFiled: September 27, 2021Publication date: April 7, 2022Inventors: Eli N. GLEZER, Martin Maria FABANI, Ryan SHULTZABERGER, Bharat SRIDHAR, Gudrun STENGEL, Christopher Jen-Yue WEI
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Publication number: 20220042087Abstract: Provided herein are methods of making, amplifying, and sequencing tagged nucleic acid complements, compositions including interposing oligonucleotide barcodes, and kits useful in obtaining long-range sequence data.Type: ApplicationFiled: October 8, 2021Publication date: February 10, 2022Inventors: Eli N. GLEZER, Martin Maria FABANI, Ryan SHULTZABERGER, Bharat SRIDHAR, Gudrun STENGEL, Christopher Jen-Yue WEI
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Publication number: 20220033895Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: October 13, 2021Publication date: February 3, 2022Inventors: Eli N. Glezer, Martin Maria Fabani, Timothy Looney, Sabrina Shore, Ryan Shultzaberger, Daan Witters
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Patent number: 11155858Abstract: Provided herein are methods of making, amplifying, and sequencing tagged nucleic acid complements, compositions including interposing oligonucleotide barcodes, and kits useful in obtaining long-range sequence data.Type: GrantFiled: December 18, 2020Date of Patent: October 26, 2021Assignee: SINGULAR GENOMICS SYSTEMS, INC.Inventors: Eli N. Glezer, Martin Maria Fabani, Ryan Shultzaberger, Bharat Sridhar, Gudrun Stengel, Christopher Jen-Yue Wei
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Publication number: 20210277461Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.Type: ApplicationFiled: March 5, 2021Publication date: September 9, 2021Inventors: Eli N. Glezer, Martin Maria Fabani, Timothy Looney, Sabrina Shore, Ryan Shultzaberger, Daan Witters
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Publication number: 20210198730Abstract: Provided herein are methods of making, amplifying, and sequencing tagged nucleic acid complements, compositions including interposing oligonucleotide barcodes, and kits useful in obtaining long-range sequence data.Type: ApplicationFiled: December 18, 2020Publication date: July 1, 2021Inventors: Eli N. GLEZER, Martin Maria FABANI, Ryan SHULTZABERGER, Bharat SRIDHAR, Gudrun STENGEL, Christopher Jen-Yue WEI
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Patent number: 9982294Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: GrantFiled: February 17, 2017Date of Patent: May 29, 2018Assignee: ILLUMINA, INC.Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
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Publication number: 20170159118Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: ApplicationFiled: February 17, 2017Publication date: June 8, 2017Applicant: Illumina, Inc.Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
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Patent number: 9574235Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: GrantFiled: October 29, 2015Date of Patent: February 21, 2017Assignee: ILLUMINA, INC.Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
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Publication number: 20160115533Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: ApplicationFiled: October 29, 2015Publication date: April 28, 2016Applicant: Illumina, Inc.Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
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Patent number: 9193999Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: GrantFiled: June 25, 2014Date of Patent: November 24, 2015Assignee: Illumina, Inc.Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
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Publication number: 20150031560Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.Type: ApplicationFiled: June 25, 2014Publication date: January 29, 2015Inventors: Martin Maria FABANI, Maria Candelaria ROGERT BACIGALUPO, John A. MOON