Abstract: A ram-body for use with a spherical bearing has an inner circumferential surface. The ram-body comprises at least a first concave section provided in said inner circumferential surface. In some examples, a second concave section may be provided diametrically opposite to the first concave section. In some examples, the concave sections may be lunular shaped. A method of manufacturing the ram-body is also described. A ram-body and spherical bearing assembly is also described.

Abstract: An actuator control arrangement comprising: a hydraulic actuator having a housing and a piston rod axially moveable within the housing between a neutral position, a retracted position and an extended position with respect to the housing in response to application of pressure to the piston rod; the arrangement further comprising a check valve moveable between a first position providing a flow path between a pressure source and the actuator, and a second position in which the flow path is closed off; and characterised by a mechanical link between the piston rod and the check valve, actuated in response to the piston rod passing a predetermined retracted position in a negative stroke direction, to set the check valve to the first position.

Abstract: The present invention provides the use of a packaging cell line for the production of VSV-G pseudotyped retroviral vector particles or virus like particles thereof, wherein said packaging cell line is negative for Low-Density Lipoprotein Receptor (LDLR), optionally said packaging cell line stably expresses VSV-G. A method for producing said VSV-G pseudotyped retroviral vector particles or virus like particles thereof is disclosed as well as said particles obtained by said method.

Abstract: An actuator control arrangement comprising: a hydraulic actuator having a housing and a piston rod axially moveable within the housing between a neutral position, a retracted position and an extended position with respect to the housing in response to application of pressure to the piston rod; the arrangement further comprising a check valve moveable between a first position providing a flow path between a pressure source and the actuator, and a second position in which the flow path is closed off; and characterised by a mechanical link between the piston rod and the check valve, actuated in response to the piston rod passing a predetermined retracted position in a negative stroke direction, to set the check valve to the first position.

Abstract: A ram-body for use with a spherical bearing has an inner circumferential surface. The ram-body comprises at least a first concave section provided in said inner circumferential surface. In some examples, a second concave section may be provided diametrically opposite to the first concave section. In some examples, the concave sections may be lunular shaped. A method of manufacturing the ram-body is also described. A ram-body and spherical bearing assembly is also described.

Abstract: A rotating element is mounted in a base body for rotation about an axis of rotation. An excitation circuit generates an excitation signal. A divider circuit divides the excitation signal into a base signal supplied to an evaluation circuit and into an outgoing signal supplied to a transceiving antenna. A waveguide circulates in an annular manner about the axis of rotation. The rotating element comprises a termination element protruding into the waveguide and has a reflective side. The transceiving antenna emits an electromagnetic signal into the waveguide propagating in two directions which is reflected from the reflective side and returned to and received by the transceiving antenna which generates in response a receiving signal supplied to the evaluation circuit which determines a position of rotation of the rotating element in relation to a reference position of rotation by evaluating the base signal and receiving signal in a resolution region.

Abstract: An angular sensor includes a base body in which a rotating element is mounted for rotation about an axis of rotation. At least one transmitting antennae is arranged on the base body and each emits a transmission signal. A reflector element extends over part of the periphery, observed tangentially in relation to the axis of rotation, reflects each transmission signal, and is arranged on the rotating element, at a radial reflector distance from the axis of rotation. A plurality of receiving antennae are arranged on the base body, the receiving antennae receiving the reflected signals as a receiving signal and supplying the receiving signal to an evaluation device. The evaluation device determines the position of rotation of the rotating element by evaluating only the receiving signals or by evaluating the receiving signals and base signals determined on the basis of the transmission signals.

Abstract: A rotating element is mounted in a base body for rotation about an axis of rotation. An excitation circuit generates an excitation signal. A divider circuit divides the excitation signal into a base signal supplied to an evaluation circuit and into an outgoing signal supplied to a transceiving antenna. A waveguide circulates in an annular manner about the axis of rotation. The rotating element comprises a termination element protruding into the waveguide and has a reflective side. The transceiving antenna emits an electromagnetic signal into the waveguide propagating in two directions which is reflected from the reflective side and returned to and received by the transceiving antenna which generates in response a receiving signal supplied to the evaluation circuit which determines a position of rotation of the rotating element in relation to a reference position of rotation by evaluating the base signal and receiving signal in a resolution region.

Abstract: The present invention discloses a chimeric antigen receptor (CAR) comprising an antigen binding domain specific for BDCA2, a population of engineered cells expressing said CAR and a pharmaceutical composition thereof. Said engineered cells are for treatment of cancer in a subject, wherein the cancerous cells of said cancer express BDCA2 such as Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).

Abstract: An angular sensor includes a base body in which a rotating element is mounted for rotation about an axis of rotation. At least one transmitting antennae is arranged on the base body and each emits a transmission signal. A reflector element extends over part of the periphery, observed tangentially in relation to the axis of rotation, reflects each transmission signal, and is arranged on the rotating element, at a radial reflector distance from the axis of rotation. A plurality of receiving antennae are arranged on the base body, the receiving antennae receiving the reflected signals as a receiving signal and supplying the receiving signal to an evaluation device. The evaluation device determines the position of rotation of the rotating element by evaluating only the receiving signals or by evaluating the receiving signals and base signals determined on the basis of the transmission signals.

Abstract: An electronics assembly for wireless transmission of at least one status information of an object comprises a motion sensor for detecting movement of the object. Upon detection of movement, the electronics assembly is set in a transport mode and, upon detection of an absence of a movement, the electronics assembly is set in a stationary mode. The electronics assembly is configured such that the wireless transmission of the at least one status information is effected only in the stationary mode.

Abstract: Disclosed are some implementations of systems, apparatus, methods and computer program products for facilitating the management of assessment environments in an eLearning environment. A user may switch between assessment environments by selecting from a menu of selectable assessment environments. Educational content may be presented within a context of a selected assessment environment and assessment tasks may be completed within the context of the selected assessment environment.

Abstract: The present invention relates to polypeptides comprising a mutant human IgG4, which mutant human IgG4 is capable of increasing the binding to and activation of immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing Fc?RIIb/c (CD32b), but not Fc?RIIa (CD32a). More specifically, the invention relates to polypeptides comprising at least one human IgG4 with a lysine at position 409 (409K), using the EU index according to Kabat et al., which IgG4 is capable of binding to human CD32b/c with a statistically significant (p=0.05) higher binding affinity than a wild-type human IgG1 and than a wild-type human IgG4, for use in the prevention and/or treatment of an autoimmune disease or allergy, as further defined in the claims.

Abstract: An actuator control arrangement is provided comprising a pair of rotary control valves used in combination to control the operation of an actuator. The rotary control valves are driven synchronously through a hydraulic or mechanical coupling. Each rotary control valve has a by-pass mode which activates in the event of a jam. In addition each rotary control valve has a mechanism for activating the by-pass mode absent any jam. The actuator control arrangement further comprises a circuit coupling a pilot control and/or a flight control computer (FCC) to one or both of the mechanisms for remotely switching the rotary control valve(s) from an active mode to a by-pass mode under control of a pilot or FCC.

Abstract: An electronics assembly for wireless transmission of at least one status information of an object comprises a motion sensor for detecting movement of the object. Upon detection of movement, the electronics assembly is set in a transport mode and, upon detection of an absence of a movement, the electronics assembly is set in a stationary mode. The electronics assembly is configured such that the wireless transmission of the at least one status information is effected only in the stationary mode.

Abstract: A method for the noise modulation of a three-phase synchronous electric motor driven using a vector regulation by means of a motor control unit. Actual values for the rotated current components id and iq may be obtained in an open-loop control system, where id corresponds to the magnetization current and iq corresponds to the torque-forming current of the synchronous motor. The actual values may be compared with predetermined reference target values, and the differences between the actual values and the reference target values may be converted into control variables to regulate the actual values (iq, id) to the reference target values. The magnetization current-forming current component (id) may be adapted using an acoustic controller to a desired acoustic state depending on an acoustic state that was measured by a measuring device and was transmitted to the motor control unit.

Abstract: An actuator control arrangement is provided comprising a pair of rotary control valves used in combination to control the operation of an actuator. The rotary control valves are driven synchronously through a hydraulic or mechanical coupling. Each rotary control valve has a by-pass mode which activates in the event of a jam. In addition each rotary control valve has a mechanism for activating the by-pass mode absent any jam. The actuator control arrangement further comprises a circuit coupling a pilot control and/or a flight control computer (FCC) to one or both of the mechanisms for remotely switching the rotary control valve(s) from an active mode to a by-pass mode under control of a pilot or FCC.

Abstract: Disclosed are examples of systems, apparatus, methods and computer program products for associating multiple e-learning development environments with a single user. A database system maintains a first database associated with a number of users within an educational content management system, with each of the users being associated with a number of login identities, and a second database associated with a number of development environments. The system processes a signup request received from a client device, the signup request being received from a client device. The system then generates or updates a development organization associated with the login identity, in response to processing the signup request. The system then processes an environment request for a new development environment received from the client device, and finally, generates or updates a development environment associated with the development organization and the login identity.

Abstract: Disclosed are examples of systems, apparatus, methods and computer program products for associating multiple e-learning identities with a single user. A database system maintains a number of users within an educational content management system, with each of the users being associated with a number of login identities. The system processes a login request received from a client device, the login request including a login identity. The system then determines a user associated with the login identity, and generates a login session for the client device. The login session is associated with the user, the login identity, at least one permission associated with the user or identity, and at least one piece of data associated with the user or identity.

Abstract: Disclosed are some implementations of systems, apparatus, methods and computer program products for facilitating the management of assessment environments in an eLearning environment. A user may switch between assessment environments by selecting from a menu of selectable assessment environments. Educational content may be presented within a context of a selected assessment environment and assessment tasks may be completed within the context of the selected assessment environment.