Abstract: The invention relates generally to pediatric dosing regimens for RSV vaccines.

Abstract: The invention relates generally to chimeric viral fusion proteins comprising the ectodomain and optionally the transmembrane domain of a first viral fusion protein (e.g., a spike protein of a coronavirus) and the cytoplasmic domain of a second viral fusion protein (e.g. RSV), immunogenic compositions comprising such chimeric proteins, and methods of use of same.

Abstract: This disclosure relates to immunogenic compositions and methods of enhancing an immune response to an antigen. In certain embodiments, the disclosure relates to virus-like carries comprising a TLR5 agonist on the exterior without an antigen.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to assigning attributes to shared artifacts in a collaborative environment and provide a method, system and computer program product for end-user based processing of different attributes for a common shared artifact in a collaborative environment. In one embodiment, a data processing system configured for end-user based processing of different attributes for a commonly shared artifact in a collaborative environment can include a collaborative environment, one or more shared artifacts disposed within the collaborative environment, and artifact processing logic. The artifact processing logic can include program code enabled to assign different attributes corresponding to different end users to a commonly shared one of the shared artifacts.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to alert management and provide a method, system and computer program product for adaptive alert management. In one embodiment of the invention, an adaptive alert management data processing system can include an alert server and multiple different alert monitors disposed in corresponding application hosts. Each of the alert monitors can be configured to establish a subscription to the alert server on behalf of at least one application view of an application issuing alerts. Finally, the system can include multiple different filter rules accessible by the alert server. Each of the filter rules can specify whether or not to suppress or display an alert received in the alert server.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to managing the scatter and flood problem of the activity-centric computing environment and provide a method, system and computer program product for sorting and filtering activities in an activity-centric computing environment. In one embodiment of the invention, a method for filtering and sorting activity objects in an activity-centric computing environment can include generating at least one activity thread of hierarchically arranged activity objects, selecting at least one filtering criterion for the activity objects, and filtering the activity objects in the activity threads. Additionally, a filtered view of the activity objects can be generated in an activity map in the activity-centric computing environment.

Abstract: A solution for managing a set of collaborative contacts is provided. Each collaborative contact includes one or more collaboration capabities, each of which corresponds to a unique collaboration tool (e.g., voice over IP, instant messaging, email, and/or the like). Identifying text can be used to search the set of collaborative conatacts and obtain a set of candidate contacts. An availabilty status for each collaboration capability of each candidate contact can be requested and a display can be generated that includes the set of candidate contacts. In one embodiment, the display can include an indication of the collaboration capabilities for one or more of the candidate contacts, and/or the availablility status for one or more collaboration capabilities. A user can use the display to request a collaboration session between the user and one or more of the candidate contacts.

Abstract: A method of handling electronic documents can include determining at least one safety parameter of an electronic document and classifying the electronic document based upon the at least one safety parameter. A restriction policy can be selected based upon the classifying step. The selected restriction policy can be implemented for handling the electronic document.

Abstract: A method, apparatus, and computer instructions for allowing areas of a display to be associated with particular instant messaging users. The present invention provides a menu option to allow a user to select whether to have instant messaging dialog windows open up in the same position as the current window, or alternatively, to have the dialog windows from a specific person open up in a specified location on the display. Thus, the instant messaging software may allow window positions to be associated and “saved” with particular users. A user may create roles or add individual people to a preferences list to allow for different instant messaging window preferences for each role or person. In this manner, a user may specify areas of the display in which an instant messaging dialog window may open according to the various roles.

Abstract: A method, apparatus, and computer instructions for predicting the availability of an instant messaging user in an instant messaging system and providing that information to a message sender. The present invention analyzes a user's collaborative data to determine the user's availability to respond to an instant message and monitors z-order movement of an instant messaging window on a user's screen to determine how much attention the user is paying to the instant messaging. The instant messaging application then uses the collaborative data and the z-order information to predict the availability of the user to respond to the instant message. This information is subsequently displayed to an instant messaging partner in the partner's instant messaging window.

Abstract: A method, apparatus, and computer instructions for sending a user's availability information to an instant messaging (IM) partner. A user predefines areas of the user's display and associates these predefined areas, or “hotspots”, with user defined messages. If the user is not available to immediately respond to an incoming message, the user may move the IM dialog window to a “hotspot” in the display. Depending upon the user-defined message associated with the “hotspot”, the IM application generates an automated response indicating the user's availability to respond to the message, and sends the message to the IM partner. The user also may predefine and associate the user's IM status with a “hotspot”. Moving an IM dialog window into a “hotspot” automatically changes the user's status based on the associated “hotspot”. This change is communicated to only the particular IM dialog window partner while other IM partners are unaffected.

Abstract: Method, system and program product for conducting an on-line meeting. An on-line meeting participant application is used to enumerate the participants, including identifying each of the individual participants to individual on-line meeting sites, and publishing an agenda to enumerated participants. Individual participant inputs are collected from the individual participants and published in accordance with participant attributes.