Patents by Inventor Martin Morad

Martin Morad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthohumol in antiarrythmic applications
    Patent number: 9980925
    Abstract: Methods for modulating Ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress Ca2+ signaling by suppressing spontaneous activity of the RyR2 receptor. Delivery of xanthohumol to a cardiocyte can be utilized in treatment of cardiac arrhythmia.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: May 29, 2018
    Assignee: University of South Carolina
    Inventors: Martin Morad, Lars Cleemann, Juan Jose Arnaiz-Cot
  • XANTHOHUMOL IN ANTIARRYTHMIC APPLICATIONS
    Publication number: 20170304220
    Abstract: Methods for modulating Ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress Ca2+ signaling by suppressing spontaneous activity of the RyR2 receptor. Delivery of xanthohumol to a cardiocyte can be utilized in treatment of cardiac arrhythmia.
    Type: Application
    Filed: April 25, 2017
    Publication date: October 26, 2017
    Inventors: Martin Morad, Lars Cleemann, Juan Jose Arnaiz-Cot
  • Method and formulations for the therapy of cystic fibrosis, Bartter's syndrome and secretory diarrheas, and for diuretic treatment
    Patent number: 5100647
    Abstract: Methods for the therapy of cystic fibrosis, Bartter's syndrome, and secretory diarrheas, and for diuretic treatment, by administering to a patient dodecahydro-7,14-methano-2H,6H-di-pyrido[1,2-a:1',2'-e][1,5]diazocine or a pharmaceutically acceptable derivative thereof are disclosed. The formulations include an aerosol formulation comprising the active ingredient in association with an aerosol propellant.
    Type: Grant
    Filed: October 2, 1990
    Date of Patent: March 31, 1992
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Zalman S. Agus, Ellie Kelepouris, Martin Morad
  • Methods of treating diseases characterized by hyperexcitability of neurons
    Patent number: 4894376
    Abstract: The invention provides methods of treating diseases characterized by hyperexcitability of neurons. An amount of a substituted pyrazinoylguanidine compound effective to regulate excitability of the neurons is administered. Substituted pyrazinoylguanidines having the formula ##STR1## wherein R is halogen and R.sup.1 is a member of the group consisting of hydrogen, benzyl and optionally substituted benzyl are useful in the invention. The invention also discloses a method of treating neurons having hyperexcitable cell membranes.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: January 16, 1990
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Martin Morad, Cha-Min Tang