Abstract: An Injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at least a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained In the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1).

Abstract: An injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at feast a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1).

Abstract: An injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at feast a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1).

Abstract: An injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at least a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1).

Abstract: A golf Swing training device comprises a club member and at least one weight member. The weight member includes a mating Structure for Securing the weight member to a complementary mating Structure in the Shaft portion of the club member. The weight member can be secured to the shaft in at least three positions including a first position at the top of the Shaft adjacent the handle, a Second position at or near the midpoint of the Shaft and a third position at or near the distal end of the shaft.

Abstract: An injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at least a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1).

Abstract: A method for forming a material for a brake disc, the method comprising the steps of: (i) providing at least one porous body; (ii) introducing into pores of the porous body one or more precursor materials for forming or depositing a ceramic material; and (iii) forming the brake disc material by forming or depositing the ceramic material from the precursor material within the pores of the body, wherein the precursor material is a liquid containing a suspension of ceramic particles and/or acid phosphate.

Abstract: A syringe (2) for dispensing a fluid, the syringe including a barrel (4) including a discharge end (10) defining a discharge passage, and a plunger (15) disposed within the barrel, the plunger being adapted to move within the barrel such that the plunger and discharge end define a variable volume chamber within the barrel and the plunger is capable of displacing fluid from the chamber through the discharge passage; wherein the syringe includes a rotational element (20a, 20b, 24a, 24b) adapted to rotate about longitudinal axis of the syringe and which has a first axial orientation relative to the discharge end of the barrel and a first stop is provided on the plunger and/or the barrel which is adapted to limit axial movement of the plunger in the first orientation of the rotational element, and the rotational element has a second axial orientation relative to the discharge end of the barrel in which the first stop is disengaged and movement of the plunger is permitted to a second stop.

Abstract: The invention relates to a dermal flowable-composition dispenser that includes a body for retaining a supply of the composition, an application portion having an application surface, and a conduit connecting the supply chamber with the application surface for facilitating the reproducible delivery of a predetermined dose of the composition to the application surface. The application surface includes a concave application surface and a front side having an upper rim enclosing the application surface and forming a depression that has a volume that is greater than or equal to the volume of the predetermine dose. Also, the application surface is configured and dimensioned such it can receive the patient's skin to allow for removal of the predetermined dose of the composition, and wherein the concave application surface is shaped such that the entire application surface contacts the patient's skin when the application surface is pressed thereagainst.

Abstract: A saw blade comprises a plate having a plurality of teeth. Each of the teeth includes a tip where the tip has a smooth curved surface welded to the plate. The tip comprises a solid piece of hard material and has a generally rounded wedge shape. A method of forming a saw blade having cutting tips welded to the plate is also provided.

Abstract: A collapsible enclosure that can be selectively moved from a raised position to a lowered position such that when the enclosure is in the raised position it provides a privacy enclosure or for housing a temporary restroom facility. When the enclosure is in the lowered position, it is easily stackable for transportation and storage. The new enclosure is entirely self-contained with no loose pieces or part that need to be assembled. The installation can be performed by a single individual with a minimal number of tools, or possibly no tools at all. The collapsible enclosure includes a top section that has a roof, a top wall member, and a top door panel, a middle section that has a middle wall member and a middle door panel, and a bottom section that has a base, a bottom wall member, and a bottom door panel.

Abstract: A method for forming a material for a brake disc, the method comprising the steps of: (i) providing at least one porous body; (ii) introducing into pores of the porous body one or more precursor materials for forming or depositing a ceramic material; and (iii) forming the brake disc material by forming or depositing the ceramic material from the precursor material within the pores of the body, wherein the precursor material is a liquid containing a suspension of ceramic particles and/or acid phosphate.

Abstract: An auto-injector for dispensing a predetermined dose of medicament is disclosed. The auto-injector includes a needle cover operative to engage an injection site. The needle cover is configured to move from a retracted position prior to a medicament dispensing operation to an extended locked position after the medicament dispensing operation. Any residual activation force remaining after the medicament dispensing operation is contained within the auto-injector and is not directed to the needle cover, thus attenuating, if not eliminating, any kickback effect.

Abstract: A wearable relaxation inducing apparatus comprises either a harness or a garment made of elastically flexible fabric tightly worn on the torso; electromechanical sensors attached to the fabric translating the breathing movements of a wearer into electric signals representing breathing rate and depth; electrically operated transducers attached to the fabric providing tactile feedback to the body about breathing; and electronic circuitry for processing the electrical signals produced by the electromechanical sensors and for operating the transducers at selected adjustable sequences and rates.

Abstract: A delivery device, in particular a breath-actuated nasal delivery device, for delivering substance, in particular one of a liquid, as a suspension or solution, or a powder containing a medicament, especially systemic or topical pharmaceuticals, or a vaccine to the nasal airway of a subject.

Abstract: The present invention provides compounds that are effective against inhibiting topoisomerase (i.e., topoisomerase I and/or topoisomerase II). These compounds are used for treating cell-proliferative disorders. In some instances, these compounds have anticancer activity, e.g., against multi-drug resistant cancers.

Abstract: The saw blade includes a plate supporting a plurality of teeth about the periphery thereof. Each tooth consists of a cutting tip supported in a tip pocket. The tips are brazed to the tip pockets with no side clearance taper created on the tips. The side faces on the tips are parallel to each other. The tip pockets are stamped into the blade using a high volume stamping process that employs a semi-circular relief at the proximate trailing corner of the tip pocket to receive the proximate trailing corner of the cutting tip. The relief can be formed in a high volume stamping process because it eliminates the need for a sharp corner. The relief accommodates the sharp edge of the cutting tip and allows the cutting tip to be properly seated on the tip pocket for connection thereto.

Abstract: The present invention provides N-aryl piperidine compounds having antiinfective activity (i.e., antibacterial, antiviral), their compositions and methods of use. The compounds of the invention prevent the entry of HIV into host cells. More particularly, the compounds are effective at in inhibiting the binding interaction of HIV glycoprotein gp120 and the cell surface receptor CD4. The compounds can be used alone or in combination with other antivirals, antiinfectives, immunomodulators, or HIV entry inhibitors. More particularly, the invention relates to the prevention and treatment of HIV infectivity and AIDS.

Abstract: An auto-injector for dispensing a predetermined dose of medicament is disclosed. The auto-injector includes a needle cover that is configured to move from a retracted position to an extended locked position. The auto-injector includes a first locking assembly to hold the needle cover in a locked retracted position and a second locking assembly to hold the needle cover in a locked extended position.

Abstract: A lightning detection system provides an estimated location of a lightning stroke. The system includes sensors, and an analyzer. Each sensor provides messages having sensor identification, an amplitude responsive to the lightning stroke, and a time of detecting the lightning stroke. The analyzer applies time corrections and amplitude corrections to improve the accuracy of determining the location of the lightning stroke. Time adjustments and amplitude adjustments for the time and amplitude corrections are recalled from a matrix accessed according to a suggested or estimated location. The matrix may be organized by coordinates of longitude and latitude.