Patents by Inventor Martin O'Brien
Martin O'Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122615Abstract: A method for removing one or more objects or materials from a body lumen includes delivering a tube and an expandable device to the body lumen to a position proximal to the one or more objects or materials. The expandable device is positioned with a lumen of the tube, and the expandable device includes a lumen extending from a distal portion to a proximal portion. The method further includes proximally retracting the tube such that the expandable device remains in the position proximal to the one or more objects or materials, distally advancing the expandable device such that the distal portion of the expandable device at least partially surrounds the one or more objects or materials, at least partially closing a distal end of the expandable device, and moving the expandable device proximally to remove the expandable device and the one or more objects or materials from the lumen.Type: ApplicationFiled: October 16, 2023Publication date: April 18, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Enda CONNAUGHTON, Anthony O'BRIEN, Aiden FLANAGAN, Charlene DEANE, Michael HUGHES, Richard CRAWFORD, Martin Lawrence FAWDRY, Stephen McCOOEY
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Publication number: 20240115287Abstract: The present disclosure provides a tissue debridement device and describes an example treatment for ANP using the tissue debridement device. The tissue debridement device has a sheath, a distal tip, and a plurality of rotating tines coupled to the distal tip and the sheath. The distal tip can be adjusted to be closer or further from the sheath to change a diameter of the rotating tines, thereby changing a cutting diameter of the tissue debridement device.Type: ApplicationFiled: October 9, 2023Publication date: April 11, 2024Inventors: Enda Connaughton, Charlene Deane, Aiden Flanagan, Richard Crawford, Martin Lawrence Fawdry, Michael Hughes, Anthony O'Brien
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Publication number: 20240065717Abstract: A cannulation device is adapted to gain access to the patient's common bile duct. In some instances, the cannulation device includes a first guidewire lumen extending through an elongate shaft and terminating at a first oblique guidewire port, and a second guidewire lumen extending through the elongate shaft and terminating at a second oblique guidewire port. In some instances, the cannulation device includes an inflatable balloon that is inflatable from a collapsed configuration to an expanded configuration in which the inflatable balloon is adapted to occlude the patient's pancreatic duct. In some instances, the cannulation device includes an expandable element that is expandable from a collapsed configuration in which the expandable element is disposed within the guidewire lumen and an extended configuration in which a portion of the expandable element extends distally from a guidewire port.Type: ApplicationFiled: August 22, 2023Publication date: February 29, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Richard Crawford, Enda Connaughton, Anthony O'Brien, Martin Lawrence Fawdry, Michael Hughes, Aiden Flanagan, Claire Guinane
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Publication number: 20230374081Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.Type: ApplicationFiled: January 9, 2023Publication date: November 23, 2023Applicant: ORAL HEALTH AUSTRALIA PTY LTDInventors: Eric Charles REYNOLDS, Neil Martin O`BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
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Publication number: 20230340795Abstract: A method of sealing a leaking crack in a structure involves drilling a delivery channel into the structure adjacent the crack and in towards the crack to join the crack. A delivery nozzle is inserted into the delivery channel to inject a sealant comprising latex and water under pressure into the crack. The sealant may be injected until the sealant forms a seepage on an exterior surface of the crack which is sprayed with a reactive agent to cure the sealant to form a skin. Thereafter further sealant may be injected via the delivery channel after the skin is formed to enhance the ingress of sealant within the crack.Type: ApplicationFiled: March 4, 2021Publication date: October 26, 2023Inventors: Eoin Daniels, Claire Sharkey, Craig Hoe, Martin O'Brien, David Whitehead
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Patent number: 11572391Abstract: Disclosed are P. gingivalis antibodies raised against a chimeric or fusion protein, wherein the chimeric or fusion protein comprises a first peptide joined directly or through a linker to a second peptide or polypeptide, wherein (A) the first peptide comprises a region of a P. gingivalis trypsin-like enzyme and (B) the second peptide or polypeptide comprises an adhesin domain of P. gingivalis.Type: GrantFiled: November 13, 2020Date of Patent: February 7, 2023Assignee: Oral Health Australia PTY LtdInventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
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Publication number: 20220339187Abstract: An antimicrobial agent comprising a selenium nanoparticle (SeNP) core and one or more superficially located antimicrobial peptide/s (AMP). The or each AMP may comprise an excess of positively charged amino acids compared to negatively charged amino acids and the AMP may comprise peptides from classes selected from polylysine, such as ?-poly-L-lysine (?-PL), polyarginine, aurein, ovispirin, melittin, magainin, cecropin, andropin, moricin, ceratotoxin, melittin, magainin, dermaseptin, bombinin, brevinin, esculentins, buforin, cathelicidin, abaecin, apidaecin, prophenin and indolicidin. Products comprising such agents, methods of producing the agents and methods of killing or retarding growth of microorganisms exposed to the agents are also disclosed.Type: ApplicationFiled: June 19, 2020Publication date: October 27, 2022Inventors: Tao Huang, Andrea Janet O'Connor, Neil Martin O'Brien-Simpson, Daniel Edward Heath
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Patent number: 11300584Abstract: An optical air data system for an air vehicle includes a LIDAR module and a data processing module. The LIDAR module is configured to emit at least three laser beams, not all located in a common plane, and perform LIDAR measurements of a backscattered component of each of the laser beams. The data processing module includes a processor and machine-readable instructions that, when executed by the processor, processes the LIDAR measurements to determine at least one optically-based air data parameter. The overlap between the laser beams and one or more fields of view of the LIDAR module may be within two meters from the LIDAR module to determine the at least one optically-based air data parameter at short range from the air vehicle.Type: GrantFiled: July 6, 2017Date of Patent: April 12, 2022Assignee: OPHIR CORPORATIONInventors: Loren M. Caldwell, Phillip E. Acott, Martin O'Brien
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Patent number: 11154589Abstract: This invention relates to compositions including antibacterial compounds. The invention also relates to the use of the compositions in methods of treating bacterial infections. In one aspect the present invention also provides a method of increasing the susceptibility of bacteria to the anti-bacterial activity of a compound, the method comprising contacting the bacteria with a star shaped peptide polymer of the invention, thereby increasing the susceptibility of the bacteria to the anti-bacterial activity of the compound. Preferably, the method further includes the step of contacting the bacteria with the compound for which the bacteria have increased susceptibility to. The invention is further relates to the combination of a star shaped peptide polymer and an anti-bacterial compound that restore the sensitivity of antibiotic resistant bacteria to antibiotics that are otherwise ineffective when administered alone.Type: GrantFiled: November 2, 2017Date of Patent: October 26, 2021Assignee: The University of MelbourneInventors: Greg GuangHua Qiao, Neil Martin O'Brien-Simpson, Shu Jie Lam, Eric Charles Reynolds
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Publication number: 20210079047Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.Type: ApplicationFiled: November 13, 2020Publication date: March 18, 2021Applicant: Oral Health Australia PTY LtdInventors: Eric Charles REYNOLDS, Neil Martin O'BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
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Patent number: 10851138Abstract: Disclosed are methods related to the generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases, such as methods of preparing P. gingivalis antibodies, comprising immunizing a non-human animal with a chimeric or fusion protein, wherein the protein comprises a first peptide joined directly or through a linker to a second peptide or polypeptide, wherein (A) the first peptide comprises a region of a P. gingivalis trypsin-like enzyme and (B) the second peptide or polypeptide comprises an adhesin domain of P. gingivalis.Type: GrantFiled: September 18, 2018Date of Patent: December 1, 2020Assignee: ORAL HEALTH AUSTRALIA PTY LTDInventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J Cross, Nada Slakeski
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Patent number: 10746901Abstract: A method for predicting arrival of a wind event at an aeromechanical structure includes sensing wind velocity in an atmospheric volume moving towards the aeromechanical structure to obtain a time series of spatially distributed wind velocity measurements, determining presence of the wind event from at least one of the distributed wind velocity measurements, and tracking the wind event based upon the time series of spatially distributed wind velocity measurements to estimate arrival time of the wind event at the aeromechanical structure. A wind-predicting system uses a lidar and a wind-predicting unit to implement this method. An aeromechanical apparatus integrates this wind-predicting system to predict wind events at the aeromechanical apparatus.Type: GrantFiled: May 19, 2015Date of Patent: August 18, 2020Assignee: Ophir CorporationInventors: Martin O'Brien, Loren M. Caldwell, Phillip E. Acott, Lisa G. Spaeth
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Publication number: 20200123328Abstract: This invention relates to antibacterial compounds and compositions thereof. The invention also relates to the use of the compounds and compositions in methods of treating bacterial infections, particularly those bacterial infections including bacteria that exhibit antibiotic resistance. More specifically, the present invention provides a star shaped peptide polymer comprising a multifunctional core with a plurality of terminal arms extending therefrom, wherein the terminal arms are statistical or random peptide copolymers of at least a cationic amino acid residue and a hydrophobic amino acid residue.Type: ApplicationFiled: November 2, 2017Publication date: April 23, 2020Inventors: Greg GuangHua Qiao, Neil Martin O'Brien-Simpson, Shu Jie Lam, Anton Richard Blencowe, Eric Charles Reynolds
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Publication number: 20190302141Abstract: An optical air data system for an air vehicle includes a LIDAR module and a data processing module. The LIDAR module is configured to emit at least three laser beams, not all located in a common plane, and perform LIDAR measurements of a backscattered component of each of the laser beams. The data processing module includes a processor and machine-readable instructions that, when executed by the processor, processes the LIDAR measurements to determine at least one optically-based air data parameter. The overlap between the laser beams and one or more fields of view of the LIDAR module may be within two meters from the LIDAR module to determine the at least one optically-based air data parameter at short range from the air vehicle.Type: ApplicationFiled: July 6, 2017Publication date: October 3, 2019Inventors: Loren M. CALDWELL, Phillip E. ACOTT, Martin O'BRIEN
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Publication number: 20190247459Abstract: This invention relates to compositions including antibacterial compounds. The invention also relates to the use of the compositions in methods of treating bacterial infections. In one aspect the present invention also provides a method of increasing the susceptibility of bacteria to the anti-bacterial activity of a compound, the method comprising contacting the bacteria with a star shaped peptide polymer of the invention, thereby increasing the susceptibility of the bacteria to the anti-bacterial activity of the compound. Preferably, the method further includes the step of contacting the bacteria with the compound for which the bacteria have increased susceptibility to. The invention is further relates to the combination of a star shaped peptide polymer and an anti-bacterial compound that restore the sensitivity of antibiotic resistant bacteria to antibiotics that are otherwise ineffective when administered alone.Type: ApplicationFiled: November 2, 2017Publication date: August 15, 2019Inventors: Greg GuangHua Qiao, Neil Martin O'Brien-Simpson, Shu Jie Lam, Eric Charles Reynolds
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Publication number: 20190194263Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.Type: ApplicationFiled: September 18, 2018Publication date: June 27, 2019Applicant: Oral Health Australia PTY LtdInventors: Eric Charles REYNOLDS, Neil Martin O'BRIEN SIMPSON, Keith J. CROSS, Nada SLAKESKI
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Patent number: 9792131Abstract: Approaches for creating a template virtual machine. An in-memory state of a virtual machine and/or a set of applications executing within the virtual machine are adjusted and/or configured based on the intended use of the template virtual machine. Thereafter, the virtual machine is established as a template virtual machine. The template virtual machine may be used to create one or more virtual machines using a copy-on-write memory process.Type: GrantFiled: May 10, 2012Date of Patent: October 17, 2017Assignee: Bromium, Inc.Inventors: Krzysztof Uchronski, Martin O'Brien, Jacob Gorm Hansen, Kiran Bondalapati, Ian Pratt, Gaurav Banga, Vikram Kapoor
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Publication number: 20170247420Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.Type: ApplicationFiled: December 6, 2016Publication date: August 31, 2017Applicant: Oral Health Australia Pty Ltd.Inventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J. Cross, Nada Slakeski
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Patent number: 9518109Abstract: The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.Type: GrantFiled: September 16, 2014Date of Patent: December 13, 2016Assignee: ORAL HEALTH AUSTRALIA PTY LTDInventors: Eric Charles Reynolds, Neil Martin O'Brien Simpson, Keith J Cross, Nada Slakeski
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Patent number: 9354906Abstract: Managing the guest operating system's eviction of memory pages from a virtual machine. A guest operating system or a hypervisor may cause one or more memory pages within a guest physical frame to become unlikely or ineligible for selection as a candidate for eviction by the guest operating system. Each of the one or more memory pages may also reside, or be intended to reside, in the memory of one or more other virtual machines. In this way, memory pages that are shared across multiple virtual machines may become less likely to be evicted, thereby using memory more efficiently.Type: GrantFiled: May 10, 2012Date of Patent: May 31, 2016Assignee: Bromium, Inc.Inventors: Krzysztof Uchronski, Martin O'Brien, Jacob Gorm Hansen, Kiran Bondalapati, Ian Pratt, Gaurav Banga, Vikram Kapoor