Patents by Inventor Martin P. Redmon

Martin P. Redmon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE SALT FORMS
    Publication number: 20230279049
    Abstract: Disclosed are various crystalline salt forms of D-Arg-Dmt-Lys-Phe-NH2.
    Type: Application
    Filed: December 2, 2022
    Publication date: September 7, 2023
    Inventors: Scott M. Duncan, Martin P. Redmon
  • CRYSTALLINE DIPEPTIDES USEFUL IN THE SYNTHESIS OF ELAMIPRETIDE
    Publication number: 20230203093
    Abstract: Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT. The crystalline forms may be used in the synthesis of elamipretide.
    Type: Application
    Filed: December 21, 2022
    Publication date: June 29, 2023
    Inventors: Scott M. Duncan, Martin P. Redmon
  • Crystalline dipeptides useful in the synthesis of elamipretide
    Patent number: 11560404
    Abstract: Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT. The crystalline forms may be used in the synthesis of elamipretide.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: January 24, 2023
    Assignee: Stealth BioTherapeutics Inc.
    Inventors: Scott M. Duncan, Martin P. Redmon
  • Crystalline salt forms
    Patent number: 11555053
    Abstract: Disclosed are various crystalline salt forms of D-Arg-Dmt-Lys-Phe-NH2.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: January 17, 2023
    Assignee: Stealth BioTherapeutics Inc.
    Inventors: Scott M. Duncan, Martin P. Redmon
  • CRYSTALLINE DIPEPTIDES USEFUL IN THE SYNTHESIS OF ELAMIPRETIDE
    Publication number: 20210292274
    Abstract: Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT.
    Type: Application
    Filed: April 7, 2021
    Publication date: September 23, 2021
    Inventors: Scott M. Duncan, Martin P. Redmon
  • Crystalline dipeptides useful in the synthesis of elamipretide
    Patent number: 10975118
    Abstract: Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: April 13, 2021
    Assignee: Stealth BioTherapeutics Corp.
    Inventors: Scott M. Duncan, Martin P. Redmon
  • CRYSTALLINE SALT FORMS
    Publication number: 20210047368
    Abstract: Disclosed are various crystalline salt forms of D-Arg-Dmt-Lys-Phe-NH2.
    Type: Application
    Filed: May 4, 2020
    Publication date: February 18, 2021
    Inventors: Scott M. Duncan, Martin P. Redmon
  • CRYSTALLINE DIPEPTIDES USEFUL IN THE SYNTHESIS OF ELAMIPRETIDE
    Publication number: 20200283476
    Abstract: Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT.
    Type: Application
    Filed: March 28, 2019
    Publication date: September 10, 2020
    Inventors: Scott M. Duncan, Martin P. Redmon
  • Crystalline salt forms
    Patent number: 10683326
    Abstract: Disclosed are various crystalline salt forms of D-Arg-Dmt-Lys-Phe-NH2.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: June 16, 2020
    Assignee: Stealth BioTherapeutics Corp.
    Inventors: Scott M. Duncan, Martin P. Redmon
  • CRYSTALLINE SALT FORMS
    Publication number: 20190382442
    Abstract: Disclosed are various crystalline salt forms of D-Arg-Dmt-Lys-Phe-NH2.
    Type: Application
    Filed: March 10, 2017
    Publication date: December 19, 2019
    Inventors: Scott M. Duncan, Martin P. Redmon
  • Purified pyrroloquinolinyl-pyrrolidine-2,5-dione compositions and methods for preparing and using same
    Patent number: 9499540
    Abstract: The present invention relates to a (±)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione dichloromethane.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: November 22, 2016
    Assignee: ArQule, Inc.
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • TOPICAL TREATMENT OF LOCALIZED SCLERODERMA
    Publication number: 20160120865
    Abstract: Disclosed are compositions and formulations for topical administration that contain a tyrosin kinase inhibitor, such as imatinib or nilotinib. The topical compositions or formulations are useful in treating scleroderma.
    Type: Application
    Filed: May 30, 2014
    Publication date: May 5, 2016
    Inventors: Mark W. Trumbore, Martin P. Redmon, Robert Alan Lafyatis, Pinaki Ranjan Majhi
  • PURIFIED PYRROLOQUINOLINYL-PYRROLIDINE-2,5-DIONE COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME
    Publication number: 20160024076
    Abstract: The present invention relates to a (±)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione dichloromethane.
    Type: Application
    Filed: September 26, 2014
    Publication date: January 28, 2016
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • Purified pyrroloquinolinyl-pyrrolidine-2,5-dione compositions and methods for preparing and using same
    Patent number: 8871933
    Abstract: The present invention relates to a form 1 and form 2 polymorph of (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione. The present invention also relates to (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds having a chiral purity greater than 99%, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising these (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: October 28, 2014
    Assignee: ArQule, Inc.
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • Purified Pyrroloquinolinyl-Pyrrolidine-2,5-Dione Compositions and Methods for Preparing and Using Same
    Publication number: 20140031551
    Abstract: The present invention relates to a form 1 and form 2 polymorph of (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione. The present invention also relates to (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds having a chiral purity greater than 99%, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising these (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds.
    Type: Application
    Filed: September 25, 2013
    Publication date: January 30, 2014
    Applicant: ArQule, Inc.
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • Purified pyrroloquinolinyl-pyrrolidine-2,5-dione compositions and methods for preparing and using same
    Patent number: 8552192
    Abstract: The present invention relates to a form 1 and form 2 polymorph of (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione. The present invention also relates to (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl) pyrrolidine-2,5-dione compounds having a chiral purity greater than 99%, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising these (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: October 8, 2013
    Assignee: ArQule, Inc.
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • Purified Pyrroloquinolinyl-Pyrrolidine-2,5-Dione Compositions And Methods For Preparing And Using Same
    Publication number: 20110160242
    Abstract: The present invention relates to a form 1 and form 2 polymorph of (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione. The present invention also relates to (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds having a chiral purity greater than 99%, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising these (?)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione compounds.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 30, 2011
    Applicant: ArQule, Inc.
    Inventors: David P. Reed, Neil R. Barnes, John C. Kane, Christopher A. Lee, Jian-Xie Chen, Martin P. Redmon
  • Hydroxy sulfonate of quinone compounds and their uses
    Patent number: 7790765
    Abstract: The present invention provides sodium 6-hydroxy-2,2-dimethyl-5-oxo-3,4,5,6-tetrahydro-2H-benzo(h)chromene-6-sulfonate, and its synthesis and uses in the treatment of cancer.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 7, 2010
    Assignee: ArQule, Inc.
    Inventors: Judit Bartis, Erika Volckova, Manish Tandon, Deirdre Lowe, Martin P. Redmon
  • Hydroxy sulfonate of quinone compounds and their uses
    Publication number: 20090028952
    Abstract: The present invention provides sodium 6-hydroxy-2,2-dimethyl-5-oxo-3,4,5,6-tetrahydro-2H-benzo(h)chromene-6-sulfonate, and its synthesis and uses in the treatment of cancer.
    Type: Application
    Filed: April 30, 2008
    Publication date: January 29, 2009
    Inventors: Judit Bartis, Erika Volckova, Manish Tandon, Deirdre Lowe, Martin P. Redmon
  • Norastemizole polymorphs
    Patent number: 6627646
    Abstract: Polymorphic crystalline forms of the antihistaminic drug norasternizole are disclosed. Processes for the production of the preferred polymorph are also disclosed.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: September 30, 2003
    Assignee: Sepracor Inc.
    Inventors: Roger P. Bakale, Chris Senanayake, Yaping Hong, Kostas Saranteas, Martin P. Redmon, Stephen A. Wald