Patents by Inventor Martin Peder Crep
Martin Peder Crep has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11345882Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: GrantFiled: August 24, 2016Date of Patent: May 31, 2022Assignee: BIOVEST INTERNATIONAL, INC.Inventors: Darrell Paul Page, Robert J. Wojciechowski, Martin Peder Crep
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Patent number: 10723993Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.Type: GrantFiled: August 24, 2016Date of Patent: July 28, 2020Assignee: BIOVEST INTERNATIONAL, INC.Inventors: Robert J. Wojciechowski, Darrell P. Page, Karl Patrick Bongers, Scott Waniger, Beverly Norris, Mark Hirschel, Thiem Chan Duong Wong, Grant Adams, Martin Peder Crep, Michael J. Gramer
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Patent number: 9534198Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: GrantFiled: September 23, 2013Date of Patent: January 3, 2017Assignee: BIOVEST INTERNATIONAL, INC.Inventors: Darrell Paul Page, Robert J. Wojciechowski, Martin Peder Crep
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Publication number: 20160362652Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: ApplicationFiled: August 24, 2016Publication date: December 15, 2016Inventors: DARRELL PAUL PAGE, ROBERT J. WOJCIECHOWSKI, MARTIN PEDER CREP
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Publication number: 20160362650Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.Type: ApplicationFiled: August 24, 2016Publication date: December 15, 2016Inventors: ROBERT J. WOJCIECHOWSKI, DARRELL P. PAGE, KARL PATRICK BONGERS, SCOTT WANIGER, BEVERLY NORRIS, MARK HIRSCHEL, THIEM CHAN DUONG WONG, GRANT ADAMS, MARTIN PEDER CREP, MICHAEL J. GRAMER
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Patent number: 9441195Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.Type: GrantFiled: October 30, 2012Date of Patent: September 13, 2016Assignee: BIOVEST INTERNATIONAL, INC.Inventors: Robert J. Wojciechowski, Darrell P. Page, Karl Patrick Bongers, Scott Waniger, Beverly Norris, Mark Hirschel, Thiem Chan Duong Wong, Grant Adams, Martin Peder Crep, Michael J. Gramer
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Publication number: 20140024012Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: ApplicationFiled: September 23, 2013Publication date: January 23, 2014Inventors: DARRELL PAUL PAGE, ROBERT J. WOJCIECHOWSKI, MARTIN PEDER CREP
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Patent number: 8540499Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: GrantFiled: November 20, 2008Date of Patent: September 24, 2013Assignee: Biovest International, Inc.Inventors: Darrell Paul Page, Robert J. Wojciechowski, Martin Peder Crep
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Publication number: 20090269841Abstract: A cell culture system for the production of cells and cell derived products includes a reusable instrumentation base device incorporating hardware to support cell culture growth. A disposable cultureware module including a cell growth chamber is removably attachable to the instrumentation base device. The base device includes microprocessor control and a pump for circulating cell culture medium through the cell growth chamber. The cultureware module is removably attached to the instrumentation base device. Cells are introduced into the cell growth chamber and a source of medium is fluidly attached to the cultureware module. Operating parameters are programmed into the microprocessor control. The pump is operated to circulate the medium through the cell growth chamber to grow cells or cell products therein. The grown cells or cell products are harvested from the cell growth chamber and the cultureware module is then disposed.Type: ApplicationFiled: November 20, 2008Publication date: October 29, 2009Applicant: Biovest International, Inc.Inventors: Robert J. Wojciechowski, Darrell Paul Page, Karl Patrick Bongers, Scott Thomas Waniger, Beverly Norris, Mark D. Hirschel, Thiem Chan Duong Wong, Martin Peder Crep, Michael J. Gramer, Grant Adams
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Publication number: 20090215022Abstract: An extra-capillary fluid cycling unit for maintaining and cycling fluid volumes in a cell culture chamber includes a housing and a first flexible reservoir extra-capillary fluid reservoir disposed in the housing. The extra-capillary fluid reservoir is in fluid communication with a cell culture chamber. A second flexible reservoir is also located in the housing, the second flexible reservoir being in fluid communication with a pressure source. A sensor plate is movably disposed in the housing between the extra-capillary reservoir and the second reservoir, wherein the second reservoir is pressurized to move the sensor plate in relation to the extra-capillary reservoir to cause fluid cycling and maintain fluid volumes in the cell growth chamber.Type: ApplicationFiled: November 20, 2008Publication date: August 27, 2009Applicant: Biovest International, Inc.Inventors: Darrell Paul Page, Robert J. Wojciechowski, Martin Peder Crep