Patents by Inventor Martin Poe

Martin Poe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitor of dihydrofolate reductase
    Patent number: 4258045
    Abstract: A group of aryl-Z-alkoxy-5-benzylpyrimidines wherein Z is oxy, thio, imino, carbonyl, carbamoyl, sulfonyl, sulfinyl or sulfamoyl has been prepared from 2,4-diamino-5-benzylpyrimidine via alkylation with either an aryl-Z-alkyl halide or a substituted glycidyl ether. These compounds are potent dihydrofolate reductase (DHFR) inhibitors which are useful as antibacterial, anti-protozoal and antitumor agents.
    Type: Grant
    Filed: November 30, 1979
    Date of Patent: March 24, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Martin Poe, William V. Ruyle