Patents by Inventor Martin Pohlchen

Martin Pohlchen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4)
    Patent number: 7892827
    Abstract: The present invention relates to a compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4), wherein the compound exhibits a synergistic mode of action in that the compound: (a) increases T cell priming or T cell expansion or the generation of memory T cells by blocking of CTLA-4, and (b) enhances effector T cell activity in tumor tissue or lymphoid tissue by blocking of CTLA-4. The compound of the invention can be a protein, a small organic molecule, a peptide, or a nucleic acid.
    Type: Grant
    Filed: November 25, 2005
    Date of Patent: February 22, 2011
    Assignee: Pieris AG
    Inventors: Gabriele Matschiner, Andreas Hohlbaum, Steffen Schlehuber, Martin Pöhlchen, Arne Skerra
  • Compound with Affinity for the Cytotoxic T Lymphocyte-Associated Antigen (Ctla-4)
    Publication number: 20090042785
    Abstract: The present invention relates to a compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4), wherein the compound exhibits a synergistic mode of action in that the compound: (a) increases T cell priming or T cell expansion or the generation of memory T cells by blocking of CTLA-4, and (b) enhances effector T cell activity in tumor tissue or lymphoid tissue by blocking of CTLA-4. The compound of the invention can be a protein, a small organic molecule, a peptide, or a nucleic acid.
    Type: Application
    Filed: November 25, 2005
    Publication date: February 12, 2009
    Inventors: Gabriele Matschiner, Andreas Hohlbaum, Steffen Schlehuber, Martin Pohlchen, Arne Skerra