Patents by Inventor Martin R. Brown

Martin R. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemosensory receptor ligand-based therapies
    Patent number: 9901551
    Abstract: Provided herein are compositions and methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions with chemosensory receptor ligands. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: February 27, 2018
    Assignee: AMBRA BIOSCIENCE LLC
    Inventors: Alain Baron, Martin R. Brown, Christopher R. J. Jones
  • Chemosensory receptor ligand-based therapies
    Patent number: 9526741
    Abstract: Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also provided herein are chemosensory receptor ligand compositions and the preparation thereof for the methods of the present invention.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: December 27, 2016
    Assignee: AMBRA BIOSCIENCE LLC
    Inventors: Alain Baron, Martin R. Brown, Christopher R. G. Jones
  • Chemosensory receptor ligand-based therapies
    Patent number: 9486463
    Abstract: Provided herein are methods of modulating hormone concentrations in a subject comprising the administration of a composition comprising a chemosensory receptor ligand, wherein the composition is adapted to deliver the ligand to one or more regions of the intestine of said subject. Also provided are methods directed to the modulation of circulating concentrations of one or more of GLP-1 (total), GLP-1 (active), GLP-2, oxyntomodulin, PYY (total), PYY 3-36, CCK, GIP, insulin, C-peptide, glycentin, uroguanylin amylin, and ghrelin (total), ghrelin (active) and glucagon.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: November 8, 2016
    Assignee: AMBRA BIOSCIENCE LLC
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R. G. Jones, Mark S. Fineman
  • Chemosensory receptor ligand-based therapies
    Patent number: 9050292
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a chemosensory receptor ligand, such as a bitter receptor ligand. Also provided herein are chemosensory receptor ligand compositions, including bitter receptor ligand compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: June 9, 2015
    Assignee: Elcelyx Therapeutics, Inc.
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R. G. Jones, Nigel R. A. Beeley, Mark S. Fineman
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20150150894
    Abstract: Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also provided herein are chemosensory receptor ligand compositions and the preparation thereof for the methods of the present invention.
    Type: Application
    Filed: September 8, 2014
    Publication date: June 4, 2015
    Inventors: Alain BARON, Martin R. BROWN, Christopher R.G. JONES
  • Chemosensory receptor ligand-based therapies
    Patent number: 8828953
    Abstract: Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also provided herein are chemosensory receptor ligand compositions and the preparation thereof for the methods of the present invention.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: September 9, 2014
    Assignee: NaZura BioHealth, Inc.
    Inventors: Alain Baron, Martin R. Brown, Christopher R. G. Jones
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20140030332
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a chemosensory receptor ligand, such as a bitter receptor ligand. Also provided herein are chemosensory receptor ligand compositions, including bitter receptor ligand compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.
    Type: Application
    Filed: January 6, 2012
    Publication date: January 30, 2014
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley, Mark S. Fineman
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20130338095
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
    Type: Application
    Filed: October 18, 2011
    Publication date: December 19, 2013
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20130303466
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
    Type: Application
    Filed: October 18, 2011
    Publication date: November 14, 2013
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley, Alain D. Baron
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20130281387
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
    Type: Application
    Filed: October 18, 2011
    Publication date: October 24, 2013
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20130281394
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.
    Type: Application
    Filed: October 18, 2011
    Publication date: October 24, 2013
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain D. Baron, Martin R. Brown, Christopher R.G. Jones, Nigel R.A. Beeley
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20120177730
    Abstract: Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a chemosensory receptor ligand, such as a bitter receptor ligand. Also provided herein are chemosensory receptor ligand compositions, including bitter receptor ligand compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.
    Type: Application
    Filed: January 6, 2012
    Publication date: July 12, 2012
    Applicant: Elcelyx Therapeutics, Inc.
    Inventors: Alain D. BARON, Martin R. BROWN, Christopher R.G. JONES, Nigel R.A. BEELEY, Mark S. FINEMAN
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20120094942
    Abstract: Provided herein are methods of modulating hormone concentrations in a subject comprising the administration of a composition comprising a chemosensory receptor ligand, wherein the composition is adapted to deliver the ligand to one or more regions of the intestine of said subject. Also provided are methods directed to the modulation of circulating concentrations of one or more of GLP-1 (total), GLP-1 (active), GLP-2, oxyntomodulin, PYY (total), PYY 3-36, CCK, GIP, insulin, C-peptide, glycentin, uroguanylin amylin, and ghrelin (total), ghrelin (active) and glucagon.
    Type: Application
    Filed: October 18, 2011
    Publication date: April 19, 2012
    Applicant: Elcelyx Therapeutics, Inc.
    Inventors: Alain D. BARON, Martin R. Brown, Christopher R.G. Jones, Mark S. Fineman
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20110065660
    Abstract: Provided herein are methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions comprising chemosensory receptor ligands. Also provided herein are chemosensory receptor ligand compositions and the preparation thereof for the methods of the present invention.
    Type: Application
    Filed: October 19, 2010
    Publication date: March 17, 2011
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain BARON, Martin R. BROWN, Christopher R.G. JONES
  • Chemosensory Receptor Ligand-Based Therapies
    Publication number: 20100267643
    Abstract: Provided herein are compositions and methods for treating diabetes, obesity, and other metabolic diseases, disorders or conditions with chemosensory receptor ligands. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
    Type: Application
    Filed: April 20, 2010
    Publication date: October 21, 2010
    Applicant: ELCELYX THERAPEUTICS, INC.
    Inventors: Alain BARON, Martin R. BROWN, Christopher R.G. JONES
  • Acrylamide-dialkylaminoacrylate-dialkylaminomethacrylate cationic polyelectrolytes and their production
    Patent number: 4628078
    Abstract: Improved performance and physical properties are obtainable from acrylamide-dialkylaminoalkyl acrylate polymers when the polymers are made by using a blend of at least about 15% dialkylaminoalkyl acrylate acid addition or quaternary ammonium salt with dialkylaminoalkyl methacrylate acid addition or quaternary ammonium salt.
    Type: Grant
    Filed: June 12, 1985
    Date of Patent: December 9, 1986
    Assignee: Allied Colloids Ltd.
    Inventors: Rodney Glover, Martin R. Brown