Abstract: The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

Abstract: Disclosed are granular formulations of herbicides that provide a means to apply non-selective herbicides to field and paddy crops and turf. Granules can be formulated with sub-particles to allow differential release of one or other active ingredient. Granules or sub-particles allow for controlled release of active ingedient such that while up to 30% of the active ingredient is available within 24 h, the remainder requires 3 to 40 days to become available. Sub-particles may also be used as conventional sprays to reduce uptake by leaves of desirable crops.

Abstract: Disclosed are granular formulations of herbicides that provide a means to apply non-selective herbicides to field and paddy crops and turf. Granules can be formulated with sub-particles to allow differential release of one or other active ingredient. Granules or sub-particles allow for controlled release of active ingredient such that while up to 30% of the active ingredient is available within 24 h, the remainder requires 3 to 40 days to become available. Sub-particles may also be used as conventional sprays to reduce uptake by leaves of desirable crops.

Abstract: Bioactive substances are imbedded or mixed into functionalized matrices to form homogenous water-insoluble solid complexes with desirable field properties such as reduced leaching in soil, improved leaf retention (rainfastness), selective unloading to roots and convenient packaging and application. Bioactive substances that may be so complexed include pharmaceutical agents and pesticides including herbicides, insecticides, bacteriocides, rodenticides, nematicide and fungicides. The matrices comprise either a monomeric-, oligomeric- or (co)polymeric backbone which may be derivatized with chemical groups that exhibit ionic (amines, carboxyls), hydrophobic, and ligand-binding interactions to form the matrix of the formulation. The various matrices may be mixed with additives or modifiers, grafted, or fused to obtain optimal properties. The matrix/pesticide formulations may be applied as granules, as suspensions, emulsions in sprays, as foams, or as coats for seeds and fertilizers.