Abstract: A linear motor conveyor system including: at least one track section comprising: electronic circuitry housed within the track section; and a rotatable segment comprising an end profile that abuts another track section to form a stepped groove sealed by a gasket. A moving element for a linear motor conveyor system including: a body; a first set of bearings attached to the body and angled to abut against a first guide rail of a conveyor system having a protrusion with opposing angled profiles; a second set of bearing attached to the body and designed to abut against a flat profile of a second guide rail of the conveyor system. A dry lubricant provided to the body and configured to lubricate a bearing surface of the linear motor conveyor system supporting the first set of bearings.

Abstract: The invention relates to a hair styling device, and in particular a multifunctional hair styling device having components which can carry out a number of different (and distinct) styling operations. The invention provides a hair styling device having a body portion and a handle portion, the body portion having an air inlet and an air outlet, an impeller between the air inlet and the air outlet and an electric motor to rotate the impeller, the handle portion having a pair of heating panels. The handle portion is separable from the body portion and can be used alone as a hair straighter, or the device can be used as a hair dryer with the handle portion attached to the body portion. The body portion can optionally include a hair curling chamber adapted for hair curling.

Abstract: Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids and agents which can provide improved properties and/or activities.

Abstract: The disclosed systems and methods for presenting information to an operator of the recreational vehicle comprising i) displaying a first graphical user interface (GUI) component representing a first set of information, ii) upon receiving a first control command, displaying, a second GUI component comprising a third GUI component and a fourth GUI component, the third GUI component representing a first controllable functionality of the recreational vehicle, the fourth GUI component representing a first modifiable setting of the first controllable functionality of the recreational vehicle, and iii) upon receiving a second control command, updating the third GUI component by representing a second controllable functionality of the recreational vehicle in replacement of the first controllable functionality and updating the fourth GUI component by representing a second modifiable setting of the second controllable functionality of the recreational vehicle in replacement of the first modifiable setting of the first c

Abstract: A computer system includes processing circuitry configured to simulate, using electrical multi-battery models, the performance of a propulsion electrical energy storage system of a vehicle based on logged vehicle routes of the vehicle, the electrical energy storage system comprising multiple electrical energy storage packs, predict a lifetime of the electrical energy storage system based on the simulated performance of the propulsion electrical energy storage system and extrapolating forward assuming a worst-case aging rate; if the predicted lifetime exceeds a predetermined lifetime, indicate that an electrical energy storage pack downgrade replacement is required, and reduce a state of charge window of the electrical energy storage system at a rate such that a predetermined minimum state of charge window is not reached before a planned electrical energy storage pack downgrade replacement.

Abstract: A method of producing a compound formula (I) the method comprising: reacting a compound of formula (II) with a compound of formula (III) wherein, R3 is hydrogen or halogen; R1 and R2 are each independently C1-C6alkoxy, or R1 and R2 together are ?O or —OCH2CH2O— or —OCH2CH2CH2O—; and optionally whereby the reaction is carried out in the presence of an oxidizer.

Abstract: Embodiments provide techniques, including systems and methods, for identifying and matching requestors and providers. For example, embodiments can display an identification pattern that is unique for a matched requestor and provider to allow the providers and requestors to quickly, easily, and accurately validate one another's identities prior to a service being provided. In some embodiments, the identification element may be presented on a provider communication device to clearly display graphics associated with an identification element to all requestors in an area so that the requestors may easily identify a matched provider.

Abstract: A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC).

Abstract: This invention generally provides two tactile stimulation modules, or “tappers”. One tapper is held by a person in each of his hands. Alternatively, a tapper is secured to each wrist or to other parts of the body on opposite sides. Each tapper is powered by a rechargeable battery, and contains both a tactile stimulation transducer, such as an electric motor having either a balanced or unbalanced mass on its output shaft, and a transceiver that communicates with a host or master. Each tapper includes at least one control button and a status indicator. Each tapper contains a micro-controller that performs tasks such as communication, motor activation, user monitoring and control, battery monitoring, low-power sleep, and algorithm execution. At least one tapper can contain at least one optional sensor, which measures a physiological function. Measurements can be used to modify performance of the tactile stimulation transducers.

Abstract: This invention relates to a hair styling device, a hair styling method, and a drive system suitable for use in the hair styling device. The invention relates in particular to a hair styling device (10; 210) for imparting a wave to a section of hair (36) without clamping the section of hair in the wave form. The device has a first forming member (24) and a second forming member (24) with a hair-receiving region (38) between the forming members. A driving member (20; 120) is movable relative to the first forming member and the second forming member to deform the section of hair in the hair-receiving region.

Abstract: The present invention relates to the field of therapeutic treatment, particularly of cell therapy based on CD16+ cells and NK (Natural Killer) cells. In particular, the invention relates to a pharmaceutical composition comprising a CD16+ cell, a NK cell or a NK cell precursor, in combination with a recombinant polypeptide comprising a modified Fc region, in particular a modified CH2 domain.

Abstract: A data processing apparatus comprises operand routing circuitry configured to prepare operands for processing, and a plurality of processing elements. Each processing element comprises receiving circuitry, processing circuitry, and transmitting circuitry. A group of coupled processing elements comprises a first processing element configured to receive operands from the operand routing circuitry and one or more further processing elements for which the receiving circuitry is coupled to the transmitting circuitry of another processing element in the group. The apparatus also comprises timing circuitry, configured to selectively delay transmission of operands within the group of coupled processing elements to cause operations performed by the group of coupled processing elements to be staggered.

Abstract: The present disclosure relates to compositions, methods and processes for the formulation and for the administration of a gene therapy agent using parvovirus e.g., adeno-associated virus (AAV) to the CNS, CNS tissues, CNS structures or CNS cells.

Abstract: The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. A system may include assembly cells each including an assembly track and assembly carriages that ride thereon and which engage components of partially-assembled cartridges. A transfer apparatus may transfer partially-assembled cartridges between the assembly cells. In another example system, cartridges may be assembled on platforms on a rotary track. The platforms may include assembly grippers with sequentially-opening clamps configured to receive the components of the partially-assembled cartridges. Related methods are also provided.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: Disclosed herein is a thermoplastic moulding composition including a) from 50 to 96.95% by weight of polyamide containing aliphatic non-branched C10-12 building blocks, selected from polyamide 6.10 and mixtures of polyamide 6.10 with polyamide 6.12, polyamide 12.12, polyamide 11 and/or polyamide 12, b) from 0 to 37% by weight of further polyamide different from component A); c) from 3 to 30% by weight of polyamide-polyether block copolymer; d) from 0.05 to 1.5% by weight of hindered amine light stabilizer, e) from 0 to 1% by weight of sterically hindered phenol oxidation retarder; f) from 0 to 20% by weight of further additives, where the total of the percentages by weight of a) through f) is 100% by weight and the total of the percentages by weight of b) and c) is not more than 40% by weight.

Abstract: A system and a method for configuring at least one variable geometry mechanism (VGM) of an aircraft engine are provided. Pass-off testing data for the aircraft engine is obtained, the pass-off testing data indicative of an actual value of at least one operating parameter of the aircraft engine. Based on the pass-off testing data, at least one trim value to be used to adjust a setting of the at least one VGM to bring the actual value of the at least one operating parameter towards a target value is determined, a running line of the aircraft engine being substantially constant when the actual value of the at least one operating parameter is at the target value. The setting of the at least one VGM is adjusted, during pass-off testing of the aircraft engine, using the at least one trim value.

Abstract: A system and method for deploying and retrieving a plurality of ocean bottom seismic nodes to and from the seabed. An autonomous underwater vehicle (AUV) is coupled to a node skid that is configured to handle the nodes. The AUV and coupled skid is lowered to and raised from the seabed and a surface vessel in a garage or basket. The skid may have a variable buoyancy system (VBS) formed of a plurality of pipes and a positive displacement pump, such that the VBS is configured to automatically control a buoyancy of the skid. The AUV and/or skid has a plurality of cameras for optical 3D stereo photogrammetry for identification, deployment, and retrieval of the nodes. Also disclosed is a method for retrieving a dead AUV from the ocean bottom by utilizing a garage and an unmanned underwater vehicle (UUV).

Abstract: A method for determining the locations of components of a location-determining system in an environment, the method comprising: providing a surveying device comprising: (i) a ranging subsystem comprising a transmitter and a receiver configured to receive signals transmitted by the receiver and reflected off objects in the environment whereby a three-dimensional map of the shape of the environment can be generated; (ii) a communication subsystem configured for transmitting signals to the said components or detecting signals from the said components; moving the surveying device in the environment whilst operating the ranging subsystem and the communication subsystem; and causing one or more processors to: (i) form the said three-dimensional map of the environment; and (ii) correlate that map with data received by or from the sensors to determine the positions of the sensors.

Abstract: TOOL TRACKING A system for determining the location of a toolpiece, wherein: the toolpiece is carried by a tool and the tool comprises an imaging device for capturing images of the environment around the tool; and the system comprises an image processor communicatively coupled to the imaging device for receiving images therefrom and having access to one or more reference images of an expected environment, the image processor being configured to compare an image captured by the imaging device with at least one reference image to identify a match therebetween and to determine in dependence on characteristics of that match the location of the toolpiece.