Abstract: There are provided systems, methods and radiotherapy devices for monitoring the position of a subject during radiotherapy, which comprise obtaining an MR image slice of a subject that exhibits through-plane distortion, obtaining a pre-treatment image slice of the subject that corresponds to the MR image slice and exhibits through-plane distortion that corresponds to the through-plane distortion of the MR image slice, and comparing the MR image slice with the corresponding pre-treatment image slice.

Abstract: The invention provides a compound of formula (1). or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: A gas filter that includes a filter medium configured to filter a gas flow propagating from an upstream facing side through the filter medium to a downstream facing side. The filter medium includes a capacitor with a first electrode, a second electrode, and a dielectric medium. The gas filter also includes a first electrical contact and a second electrical contact such that the first electrical contact is electrically connected via a first resistor to a branching point and the second electrical contact is electrically connected via a second resistor the same branching point. Further, the first electrode is preferably electrically connected to such branching point and the second electrode is preferably electrically connected to the second electrical contact.

Abstract: Wearable systems and method for operation thereof incorporating headset and controller localization using headset cameras and controller fiducials are disclosed. A wearable system may include a headset and a controller. The wearable system may alternate between performing headset tracking and performing controller tracking by repeatedly capturing images using a headset camera of the headset during headset tracking frames and controller tracking frames. The wearable system may cause the headset camera to capture a first exposure image an exposure above a threshold and cause the headset camera to capture a second exposure image having an exposure below the threshold. The wearable system may determine a fiducial interval during which fiducials of the controller are to flash at a fiducial frequency and a fiducial period. The wearable system may cause the fiducials to flash during the fiducial interval in accordance with the fiducial frequency and the fiducial period.

Abstract: A linear motor conveyor system including: at least one track section comprising: electronic circuitry housed within the track section; and a rotatable segment comprising an end profile that abuts another track section to form a stepped groove sealed by a gasket. A moving element for a linear motor conveyor system including: a body; a first set of bearings attached to the body and angled to abut against a first guide rail of a conveyor system having a protrusion with opposing angled profiles; a second set of bearing attached to the body and designed to abut against a flat profile of a second guide rail of the conveyor system. A dry lubricant provided to the body and configured to lubricate a bearing surface of the linear motor conveyor system supporting the first set of bearings.

Abstract: Example steering wheel actuator device for a steer-by-wire steering system of a vehicle are disclosed herein. An example steering wheel actuator device includes at least one steering wheel angle measuring device to measure a steering wheel angle of a steering wheel, a motor device to generate a motor torque counteracting a driver torque applied to the steering wheel, a control device, and an electrical energy source that supplies the steering wheel actuator device with electrical energy. The actuator device has an electrical energy storage device is configured to supply at least one steering wheel angle measuring device with stored electrical energy if the steering wheel actuator device is not supplied with electrical energy by the electrical energy source. The electrical energy storage device can preferably be charged with electrical energy generated by the motor device if the applied driver torque surpasses the motor torque.

Abstract: A data processing apparatus comprises operand routing circuitry configured to prepare operands for processing, and a plurality of processing elements. Each processing element comprises receiving circuitry, processing circuitry, and transmitting circuitry. A group of coupled processing elements comprises a first processing element configured to receive operands from the operand routing circuitry and one or more further processing elements for which the receiving circuitry is coupled to the transmitting circuitry of another processing element in the group. The apparatus also comprises timing circuitry, configured to selectively delay transmission of operands within the group of coupled processing elements to cause operations performed by the group of coupled processing elements to be staggered.

Abstract: Methods of producing bioconjugates of O-antigen polysaccharides covalently linked to a carrier protein using recombinant host cells are provided. The recombinant host cells used in the methods described herein encode a particular oligosaccharyl transferase enzyme depending on the O-antigen polysaccharide bioconjugate to be produced. The oligosaccharyl transferase enzymes can be PglB oligosaccharyl transferase or variants thereof. Also provided are compositions containing the bioconjugates, and methods of using the bioconjugates and compositions described herein to vaccinate a subject against extra-intestinal pathogenic E. coli. (ExPEC).

Abstract: An antiperspirant aerosol composition comprising a three-component mixture of propellant, ethanol and a lipid mixture consisting of glycerol monolaurate and isostearyl alcohol at a ratio of from 25:75 to 45:55, wherein the propellant content of the three-component mixture is from 40 to 87.5%; the ethanol content of the three-component mixture is from 10 to 57.5% and the lipid content of the three-component mixture is from 2.5% up to a maximum equal to the sum of 4.805 and the ethanol content multiplied by 0.115.

Abstract: There is provided a seal assembly comprising: a first component and a second component spaced apart from the first component so as to define a passage for the transfer of fluid from an inlet of the seal assembly to an outlet of the seal assembly, wherein the first component comprises a concavity at least partially defining the passage, and wherein no part of the second component extends into the portion of the passage bounded by the concavity.

Abstract: A metal powder-based manufacturing system is provided and comprises: a sealed vessel defining a manufacturing chamber; a metal transformation/conversion unit contained in the manufacturing chamber and configured to heat a metal-based feedstock for transformation/conversion; an inert gas source in gas communication with the manufacturing chamber to supply inert gas therein, the inert gas source being operatively connected to the manufacturing chamber through an inert gas line; and at least one gas purifying unit in gas communication with the manufacturing chamber to purify the inert gas to obtain a purified inert gas having an oxygen partial pressure below about 100 ppb. A process for transforming/converting metal in a purified inert gas atmosphere.

Abstract: A diesel fuel composition including (a) a quaternary ammonium salt additive; and (b) one or more nitrogen-free detergents; wherein the quaternary ammonium salt additive includes the quaternised reaction product of a hydrocarbyl substituted succinic acid derived acylating agent and a compound able to react with said acylating agent and which includes a tertiary amine group; wherein each molecule of the hydrocarbyl substituted succinic acid derived acylating agent includes on average at least 1.2 succinic acid moieties.

Abstract: An electronic user device includes inclusion list storage with electronically readable memory, for storing an inclusion list and the inclusion list indicating included logical IDs. The device also has a security module app that receives a cellular broadcast message and extracts logical IDs therefrom. This processes a targeted cellular broadcast message embedded in the payload of the cellular broadcast message, based on whether a logical ID, also embedded in the payload, of the targeted cellular broadcast message is on the inclusion list. It then formats it for consumption by an electronic user device app that receives data via a data channel when available.

Abstract: A method of cleaning up deposits in an indirect injection diesel engine, the method including combusting in the engine a diesel fuel composition having a quaternary ammonium salt additive; and optionally one or more further nitrogen-containing detergents; wherein the quaternary ammonium salt additive comprises the quaternised reaction product of a hydrocarbyl substituted succinic acid derived acylating agent and a compound able to react with said acylating agent and which includes a tertiary amine group; wherein each molecule of the hydrocarbyl substituted succinic acid derived acylating agent includes on average at least 1.2 succinic acid moieties.

Abstract: A method of cleaning up internal diesel injector deposits in a severely fouled engine, the method including combusting in the engine a diesel fuel composition having (a) a quaternary ammonium salt additive; and (b) one or more further nitrogen-containing detergents; in which the quaternary ammonium salt additive includes the quaternised reaction product of a hydrocarbyl substituted succinic acid derived acylating agent and a compound able to react with said acylating agent and which includes a tertiary amine group; in which each molecule of the hydrocarbyl substituted succinic acid derived acylating agent includes on average at least 1.2 succinic acid moieties.

Abstract: An ultrasonic level sensor (1) for monitoring the level of a liquid in a vessel comprises a main housing (3) having a lower part (5) and an upper part (6). An ultrasonic transducer (19) having an output face (25), through which ultrasonic signals are transmitted and received is housed in a sub-housing (39) located in an engagement recess (17) in the lower part (5). A communicating aperture (24) accommodates ultrasonic signals transmitted by the ultrasonic transducer (19) to and from the liquid surface, the level of which is to be monitored. The sub-housing (39) comprises a cylindrical side wall (40) extending upwardly from a protective element (35) for protecting the ultrasonic transducer (19).

Abstract: The present invention relates to a process for preparing an aqueous polymer dispersion comprising using a first aqueous mixture M(1) and a second aqueous mixture M(2), an aqueous polymer dispersion obtainable or obtained by said process and a use of said dispersion as a binder, preferably for decorative coatings. Further, the present invention relates to a coating, such as paint and paint formulation comprising said dispersion.

Abstract: The present invention relates to aqueous polymer latexes of film-forming copolymer particles obtainable by aqueous emulsion polymerisation of monoethylenically monomers M, which mainly comprise non-ionic monomers of the group consisting of alkyl(meth)acrylates, cycloalkyl(meth)acrylates and monovinylaromatic hydrocarbon monomers and which additionally comprise 0.01 to 1% by weight, based on the total weight of monomers M, of at least one monoethylenically unsaturated monomer M2 having a hydrolysable silane group; and 0.1 to 2% by weight, based on the total weight of monomers M, of at least one monoethylenically unsaturated monomer M3 having an acidic phosphate group, or a salt thereof and where the copolymer particles in the polymer latex have volume median particle diameter of at least 250 nm, as determined by dynamic light scattering according to the ISO 13321:1996 standard.

Abstract: Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids and agents which can provide improved properties and/or activities.