Patents by Inventor Martin Rossing
Martin Rossing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20090069738Abstract: Electrode structures for implantation include an electrode, an elastic backing attached to the electrode, and a sequestered drug on the backing or the electrode which is released to control and/or limit the growth of scar tissue. The elastic backing includes a tissue contacting side which contacts a tissue structure, and an exposed side away from the tissue contacting side. The electrode structure can be used to activate baroreceptors, and the backing is elastic and can stretch and retract with the tissue structure, for example the carotid sinus. The electrode and the sequestered drug can be positioned on the tissue contacting side so the drug is released near the electrode. The backing can be made from an insulating material and limit diffusion of the drug toward the exposed side, permitting scar tissue to grow near the exposed side to maintain positioning of the electrode.Type: ApplicationFiled: July 16, 2008Publication date: March 12, 2009Applicant: CVRX, Inc.Inventors: Martin A. Rossing, Robert S. Kieval, Mary L. Cole
-
Patent number: 7499747Abstract: Methods and systems for external baroreflex activation allow a physician to characterize a patient's response to baroreflex activation prior to providing baroreflex activation therapy. Methods generally include applying a baroreflex activation stimulus to a patient, measuring one or more physiological parameters of the patient, and determining the extent to which the baroreflex activation causes a baroreflex response. Multiple stimuli of different intensities and/or from different locations may be compared. Systems include one or more external baroreflex activation devices and one or more physiological parameter measuring devices. Optionally, a system may also include one or more fully or partially implantable devices for providing baroreflex activation therapy.Type: GrantFiled: March 2, 2005Date of Patent: March 3, 2009Assignee: CVRx, Inc.Inventors: Robert S. Kieval, Martin A. Rossing
-
Patent number: 7499742Abstract: Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.Type: GrantFiled: March 27, 2003Date of Patent: March 3, 2009Assignee: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20090030262Abstract: Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.Type: ApplicationFiled: October 3, 2008Publication date: January 29, 2009Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin Rossing
-
Patent number: 7480532Abstract: Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.Type: GrantFiled: October 20, 2004Date of Patent: January 20, 2009Assignee: CVRX, Inc.Inventors: Robert S. Kieval, Martin A. Rossing
-
Publication number: 20080288017Abstract: Methods and systems for external baroreflex activation of a baroreceptor system of a patient from a stimulator external to the patient. The method and devices, enable baroflex therapy on a temporary basis and/or assess the response of a patient to such baroreflex therapy.Type: ApplicationFiled: February 27, 2008Publication date: November 20, 2008Applicant: CVRx, INC.Inventors: Robert S. Kieval, Martin A. Rossing, Robert J. Cody
-
Publication number: 20080215111Abstract: Devices, systems and methods are described which control blood pressure, nervous system activity, and neurohormonal activity by activating baroreceptors. By selectively and controllably activating baroreceptors, the present invention reduces excessive blood pressure, sympathetic nervous system activity and neurohormonal activity, thereby minimizing their deleterious effects on the heart, vasculature and other organs and tissues. A baroreceptor activation device is positioned near a low-pressure baroreceptor, preferably in the venous system, heart, or pulmonary vasculature.Type: ApplicationFiled: October 31, 2007Publication date: September 4, 2008Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin Rossing
-
Publication number: 20080208286Abstract: Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.Type: ApplicationFiled: April 30, 2008Publication date: August 28, 2008Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin Rossing
-
Publication number: 20080177348Abstract: An implantable stimulator, having at least one electrode contact array comprising multiple electrode contacts disposed on an external surface of said stimulator. The electrode contacts are configured to have a first polarity. At least one additional electrode contact is disposed on the external surface, the at least one additional electrode contact is configured to have a second polarity. One or more of the electrode contacts disposed on the stimulator are configured to deliver at least one or more of a monopolar stimulation and a multipolar stimulation.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080177339Abstract: A stimulation system for a nerve, including a cuff configured and arranged to be placed, at least partially, around the nerve, and a plurality of electrode contacts disposed on the cuff such that distances between a first electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the first electrode contact are different.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRX, Inc.Inventors: Stephen L. Bolea, Robert S. Kival, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080177365Abstract: An implantable medical device, having a neural stimulator adapted to generate neural stimulation signals, an electrode configuration tester for testing a first electrode configuration for stimulating a desired neural target, and a controller. The controller is configured to control the neural stimulator to selectively provide a first neural stimulation signal with appropriate signal characteristics to stimulate the desired neural target using the first electrical configuration and a second neural stimulation signal with appropriate signal characteristics to stimulate the desired neural target using a second electrode configuration, and adapted to communicate with the electrode configuration tester and to respond to an indication that an efficacy of the first electrode configuration is lower than a threshold by providing the neural stimulation using the second neural stimulation signal.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080177364Abstract: An electrode assembly for an implantable medical device, including a spine, and a plurality of electrodes protruding from the spine. At least two electrodes protrude from the spine in opposing directions and define a nerve-receiving channel. When the electrode assembly is not coupled to a nerve and the electrodes are in a relaxed state position, the nerve receiving channel comprises a cross-sectional area that is substantially less than a cross-sectional area of a nerve to which the electrode assembly is adapted to be coupled. And when coupled to the nerve, each electrode wraps around and directly contacts at least 60% of the circumference of the nerve.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080177366Abstract: A stimulator arrangement for a nerve, having a cuff configured and arranged to be placed around the nerve. The cuff includes a first edge, and defines a plurality of indentations along the first edge of the cuff. A plurality of electrodes are disposed on the cuff.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080177349Abstract: An apparatus for insertion into a blood vessel and for modulating the baroreflex system of a mammal includes an expandable support member for engaging a wall of a blood vessel at a desired location where baroreceptors are located, and at least one electrode connected with the expandable support member. The at least one electrode is arranged to selectively deliver electric current to modulate the baroreceptors. The apparatus further includes an insulative material attached to at least a portion of the expandable support member for isolating blood flowing through the vessel from the electric current delivered by the at least one electrode.Type: ApplicationFiled: October 31, 2007Publication date: July 24, 2008Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin Rossing
-
Publication number: 20080172104Abstract: The present invention is an apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. The apparatus includes a pulsed electric field generator and at least one electrode electrically coupled to the pulsed electric field generator. The electrode is configured for intravascular delivery, and extravascular placement, via an intra-to-extravascular approach. The electrode is configured for extravascular delivery of a pulsed electric field to induce neuromodulation.Type: ApplicationFiled: October 31, 2007Publication date: July 17, 2008Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin Rossing
-
Publication number: 20080171923Abstract: An apparatus capable of being implanted in a patient's body, including a posture sensor, a heart rate sensor, and a processor coupled to the posture sensor and the heart rate sensor. The processor is configured to measure the patient's heart rate via the cardiac signal sensor, detect a change in a posture of the patient's body via the posture sensor, and determine an autonomic tone of the patient's body based on the patient's heart rate measured during a time period corresponding to the change in posture.Type: ApplicationFiled: October 31, 2007Publication date: July 17, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080172101Abstract: A system for stimulation, including an implantable pulse generator, a lead comprising an array body disposed at a distal end of the lead and a plurality of electrodes concentrically arranged on the array body, and a plurality of conductors, wherein one of the conductors is attached to each electrode and wherein the conductors are configured and arranged to couple the electrodes to the implantable pulse generator.Type: ApplicationFiled: October 31, 2007Publication date: July 17, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080167693Abstract: The present invention comprises a neural stimulator having an output to deliver neural stimulation pulses, a sensor to sense a reference signal indicative of cardiac cycles each including a predetermined type timing reference event, the sensor being external to the circulatory system. The neural stimulator further includes detection circuitry coupled to the sensor to detect the predetermined type timing reference event, and a control circuit having an offset interval generator and a pulse delivery controller.Type: ApplicationFiled: October 5, 2007Publication date: July 10, 2008Applicant: CVRx, Inc.Inventors: Robert S. Kieval, Martin A. Rossing, Eric D. Irwin, John R. Brintnall
-
Publication number: 20080167694Abstract: A system for providing neural stimulation, including an activity monitor to sense activity and provide a signal indicative of the activity and a neural stimulator. The neural stimulator includes a pulse generator to provide a neural stimulation signal adapted to provide a neural stimulation therapy, and a modulator to receive the signal indicative of the activity and modulate the neural stimulation signal based on the signal indicative of the activity to change the neural stimulation therapy.Type: ApplicationFiled: October 31, 2007Publication date: July 10, 2008Applicant: CVRx, Inc.Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
-
Publication number: 20080167696Abstract: A method and apparatus for stimulation of a baroreflex system of a patient is provided. A method comprises establishing a therapy regimen including at least one pulse which includes at least two phases. Each phase has a polarity which is different than that of the other phase. The baroreflex system of the patient is activated with at least one baroreflex activation device which is responsive to the therapy regimen.Type: ApplicationFiled: December 21, 2007Publication date: July 10, 2008Applicant: CVRx, Inc.Inventors: Adam W. Cates, Martin A. Rossing