Patents by Inventor Martin Rowbottom

Martin Rowbottom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20050038056
    Abstract: GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein n, R1a, R1b, R1c, R2a, R2b, R3, R4, R5, R6 and X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Application
    Filed: July 6, 2004
    Publication date: February 17, 2005
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Charles Huang, Chen Chen, Yongsheng Chen, Zhiqiang Guo, Warren Wade, Martin Rowbottom, Jaimie Rueter
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20040266773
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: April 26, 2004
    Publication date: December 30, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Chen Chen, Dongpei Wu, Zhiqiang Guo, Martin Rowbottom
  • Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
    Publication number: 20040259931
    Abstract: Melanin-concentrating hormone (MCH) receptor antagonists are disclosed having utility for the treatment of MCH receptor-based disorders such as obesity.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 23, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Val Goodfellow, Martin Rowbottom, Brian P. Dyck, Junko Tamiya, Mingzhu Zhang, Jonathan Grey, Troy D. Vickers, Mehrak Kiankarimi, Warren Wade, Sarah Clough Hudson
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Patent number: 6750350
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, R1, R2, R3a, R3b, R4, R5, R6, and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: June 15, 2004
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Chen Chen, Dongpei Wu, Zhiqiang Guo, Martin Rowbottom
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20040048884
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: February 6, 2003
    Publication date: March 11, 2004
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Yun-Fei Zhu, Chen Chen, Fabio C. Tucci, Zhiqiang Guo, Timothy D. Gross, Martin Rowbottom, R. Scott Struthers
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Patent number: 6608197
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, Q, R1, R2, R3a, R3b, R4, R5, R6 and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: August 19, 2003
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Yun-Fei Zhu, Chen Chen, Fabio C. Tucci, Zhiqiang Guo, Timothy D. Gross, Martin Rowbottom, R. Scott Struthers
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20030073693
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: August 2, 2002
    Publication date: April 17, 2003
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Chen Chen, Dongpei Wu, Zhiqiang Guo, Martin Rowbottom
  • Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
    Publication number: 20020132820
    Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women.
    Type: Application
    Filed: January 25, 2001
    Publication date: September 19, 2002
    Applicant: Neurocrine Biosciences, Inc.
    Inventors: Yun-Fei Zhu, Chen Chen, Fabio C. Tucci, Zhiqiang Guo, Timothy D. Gross, Martin Rowbottom, R. Scott Struthers