Abstract: An anti-CLEC12A polypeptide generally includes an amino acid sequence having at least 90% amino acid similarity to SEQ ID NO:14. In some embodiments, anti-CLEC12A polypeptide may be incorporated into an anti-CLEC12A biologic. In some of these embodiments, the anti-CLEC12A biologic can be a bi-specific Killer engager molecule (BiKE), a tri-specific Killer engager molecule (TriKE), a tetra-specific Killer engager molecule (TetraKE), a penta-specific Killer engager molecule (PentaKE), a bi-specific T cell engager molecule (BiTE), a tri-specific T cell engager molecule (TriTE), tetra-specific T cell engager molecule (TetraTE), a penta-specific T cell engager molecule (PentaTE), a chimeric antigen receptor, a full antibody, an antibody-drug conjugate (ADC) molecule, a targeted delivery construct, or a labeling construct.

Abstract: A knockdown carrier for a plurality of juxtaposed rectangular frames supporting canvas paintings and similar artwork, to bind and maintain them in spaced relation by means of pairs of rigid bars at longitudinally displaced points along said frames. Each pair of bars is provided with adjustably fixed spacer members which extend inwardly between the frames, with the respective members at the top and bottom being in alignment with each other to accommodate frames of different thicknesses. A flexible band encompasses the outer portions of the superposed rigid bars and the frames therebetween to bind and integrate the assembly for storage or transport, and in the latter case, a balanced handle device is detachably connected between the longitudinally displaced binding and spacing units. Stretcher rods between the bottom rigid bars and stabilizer buses connected between the top rigid bars may be used as accessory devices to insure the tightness of the individual and groups of frame assemblies.