Abstract: A computer-implemented method for determining a control strategy for controlling a handling process of at least one handling device for handling piece goods includes detecting or obtaining at least one piece good information of at least one piece good which has been handled by the handling device, transmitting the at least one piece good information to a data center, determining at least one key performance indicator of the handling process of the handling device based on the at least one piece good information, determining a control strategy for the at least one handling device based on the at least one key performance indicator, a related computer program and a related handling device.

Abstract: A computer-implemented method, a device for data processing and a computer system for controlling a control device of a conveyor system to achieve an alignment and/or a defined spacing of piece goods, wherein the control of the control device is determined by an agent acting according to Reinforcement Learning methods. An individual, local state vector of predefined dimension that is the same for all the piece goods is created for each of the piece goods and an action vector is selected from an action space according to a strategy that is the same for all piece goods for the current state vector of this piece good. These action vectors are projected onto the conveying elements, wherein conflicts are resolved. After a cycle time has elapsed, state vectors are created again for each piece good and evaluated with rewards and the strategy is adjusted.

Abstract: An isolated nucleic acid molecule comprising a nucleotide sequence derived from a vertebrate animal, said nucleotide sequence codes for a polypeptide that is capable of at least partially complementing the phenotype of an animal having the anx/anx genotype as described in Maltais et al., J. Hered., 1984, 75:468-472, or a similar genotype and the polypeptide encoded by the nucleotide sequence is useful for controlling food or feed intake or body weight in animals including humans. Antibodies to the polypeptide can be used as diagnostic agents or for therapeutic purposes. Receptors for the polypeptide or antibodies to the receptors and/or polypeptide can be used to block, inhibit or enhance the biological activity of the polypeptide.

Abstract: Methods of detecting expanded nucleotide repeats in genomic DNA in a biological sample are disclosed and methods for the diagnosis of pathological and potentially pathological conditions in an individual based on the detection of the presence of expanded nucleotide repeats.