Patents by Inventor Martin Sebastian Denzel

Martin Sebastian Denzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF IDENTIFYING PATIENTS WITH BORTEZOMIB RESISTANT MULTIPLE MYELOMA AND OTHER BLOOD DISEASES
    Publication number: 20220145396
    Abstract: The present application relates to an in vitro method and a diagnostic kit for identifying resistance to bortezomib treatment in a patient in need thereof by detecting a substitution in the amino acid sequence of the polypeptide ?5 (PSMB5). The present application also relates to a composition and preferably to a synergistic composition of bortezomib and a further drug suitable for the treatment of a patient suffering from a disease selected from the group comprising multiple myeloma, mantle cell lymphoma, non-Hodgkin's lymphoma TEMPI syndrome, light chain deposition disease (LCDD), IgG4-related disease, and Scleromyxedema.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 12, 2022
    Inventors: Roman-Ulrich Muller, Kira Allmeroth, Moritz Horn, Martin Sebastian Denzel